ChemicalBook > CAS DataBase List > 8-Hydroxyquinoline-N-oxide

8-Hydroxyquinoline-N-oxide

Product Name
8-Hydroxyquinoline-N-oxide
CAS No.
1127-45-3
Chemical Name
8-Hydroxyquinoline-N-oxide
Synonyms
NSC 21656; NSC 2165;2-METHYLOXINE;OXINE N-OXIDE;1-Oxy-quinolin-8-ol;TIMTEC-BB SBB009099;8-Hydroxyquinoline-N;8-QUINOLINOL-1-OXIDE;8-QUINOLINOL N-OXIDE;Quinolin-8-ol N-oxide
CBNumber
CB9112579
Molecular Formula
C9H7NO2
Formula Weight
161.16
MOL File
1127-45-3.mol
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8-Hydroxyquinoline-N-oxide Property

Melting point:
135-138 °C (lit.)
Boiling point:
267 °C(lit.)
Density 
1.2480 (rough estimate)
refractive index 
1.5050 (estimate)
Flash point:
139 °C
storage temp. 
Inert atmosphere,2-8°C
solubility 
Soluble in Acetone, Chloroform, Dichloromethane, Ethyl Acetate and Methanol
pka
6.03±0.30(Predicted)
form 
Solid
color 
Yellow
BRN 
128737
CAS DataBase Reference
1127-45-3(CAS DataBase Reference)
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Safety

Hazard Codes 
N,Xi
Risk Statements 
50/53-36/37/38
Safety Statements 
60-61-24/25-22-36/37/39-27-26
RIDADR 
UN 3077 9/PG 3
WGK Germany 
3
RTECS 
VC8238500
F 
3-10
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P272Contaminated work clothing should not be allowed out of the workplace.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

P363Wash contaminated clothing before reuse.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
122335
Product name
8-Quinolinol N-oxide
Purity
98%
Packaging
10g
Price
$126.8
Updated
2024/03/01
Sigma-Aldrich
Product number
122335
Product name
8-Quinolinol N-oxide
Purity
98%
Packaging
5g
Price
$175
Updated
2023/06/20
TCI Chemical
Product number
H1272
Product name
8-Hydroxyquinoline N-Oxide
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$48
Updated
2024/03/01
TCI Chemical
Product number
H1272
Product name
8-Hydroxyquinoline N-Oxide
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$151
Updated
2024/03/01
TRC
Product number
H953270
Product name
8-Hydroxyquinoline N-Oxide
Packaging
5g
Price
$80
Updated
2021/12/16
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8-Hydroxyquinoline-N-oxide Chemical Properties,Usage,Production

Description

A quinoline derivative that displays mutagenic activity. It suppresses luminescence of an indicator bacterium that is named Photobacterium phosphoreum. This chemical forms two kinds of complexes with palladium (II) and Gold (III). One kind is an ion-associated compound containing hydrogen bond and hte other is the six membered metal chelates containing metal-oxygen bonds.

Chemical Properties

Yellow Crystalline Solid

Uses

A quinoline derivative; shows mutagenic activity.

Definition

ChEBI: 8-hydroxyquinoline N-oxide is a quinoline N-oxide carrying a hydroxy substituent at position 8. It is a monohydroxyquinoline and a quinoline N-oxide. It is functionally related to a quinolin-8-ol. It is a conjugate acid of an 8-hydroxyquinoline N-oxide(1-).

General Description

8-Quinolinol N-oxide is a toxicant which can suppress luminescence of an indicator bacterium Photobacterium phosphoreum. It forms two types of complexes with gold(III) and palladium(II): type I are ion-associated compounds containing hydrogen bond and the other is the six-membered metal chelates containing metal-oxygen bonds.

Synthesis

8-hydroxyquinoline-N-oxide was synthesized from 8-hydroxyquinoline. A stirred solution of 8-hydroxyquinoline (25.00 g, 172.2 mmol) in 550 ml of CHCl3 was cooled to 0° C., and 3 -chloroperoxybenzoic acid (40.00 g, 80% Tech. grade *0.231 mmol=0.185 mmol) was added slowly over 3 minutes. The solution was kept at 0° C. and stirred for 3 hours. During this period, the 3-chlorobenzoic acid byproduct precipitated. The 3-chlorobenzoic acid was removed by filtration and the orange filtrate was concentrated to dryness and the remaining solid was triturated with 2% NH40 H (2*200 ml). The solid was isolated on a frit and washed with H2O.

8-Hydroxyquinoline-N-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

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8-Hydroxyquinoline-N-oxide Suppliers

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View Lastest Price from 8-Hydroxyquinoline-N-oxide manufacturers

Henan Bao Enluo International TradeCo.，LTD
Product
8-Hydroxyquinoline-N-oxide 1127-45-3
Price
US $100.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000tons
Release date
2023-06-19
Hebei Zhanyao Biotechnology Co. Ltd
Product
8-Hydroxyquinoline-N-oxide 1127-45-3
Price
US $100.00/Kg/Bag
Min. Order
1Kg/Bag
Purity
Above 99%
Supply Ability
5000kg/month
Release date
2021-03-08
Hebei Zhanyao Biotechnology Co. Ltd
Product
8-Hydroxyquinoline-N-oxide 1127-45-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-14

1127-45-3, 8-Hydroxyquinoline-N-oxideRelated Search:

8-HYDROXYOCTANOIC ACID 3-CHLOROPYRIDINE N-OXIDE ISOQUINOLINE N-OXIDE (4-METHOXY-PYRIDIN-2-YL)-METHANOL 4-(4-Methoxyphenyl)butyric acid 4-(4-HYDROXYPHENYL)BUTANOIC ACID 8-Hydroxyquinoline OXINE-COPPER 8-Hydroxyquinoline sulfate monohydrate Quinoline-N-oxide 8-Hydroxyquinoline-N-oxide QUINOLINE N-OXIDE HYDRATE Quinoline CHEMBRDG-BB 5175127 4-HYDROXYQUINOLINE-N-OXIDE 2-HEPTYL-4-HYDROXYQUINOLINE-N-OXIDE,2-HEPTYL-4-HYDROXYQUINOLINE-1-OXIDE nonyl-4-hydroxyquinoline-N-oxide 5-[(2-Hydroxy-3,5-dinitrophenyl)azo]-8-hydroxyquinoline 1-oxide

  • 8-hydroxyquinoleine-N-oxide
  • NSC 21656
  • 8-Hydroxyquinoline 1-Oxide
  • o-Hydroxyquinoline N-Oxide
  • 8-Hydroxychinolin-N-oxid
  • 1-oxido-8-quinolin-1-iumolate
  • 1-Oxidoquinolin-1-ium-8-ol
  • 1-Oxylato-8-hydroxyquinoline-1-ium
  • 8-Hydroxyquinoline-N-oxide,99%
  • 8-Hydroxyquinoline-N
  • Quinolin-8-ol N-oxide
  • 8-Quinolinol N-oxide 98%
  • 1-Oxy-quinolin-8-ol
  • 8-hydroxyquinoline-oxide
  • 8-QUINOLINOL-1-OXIDE
  • 8-QUINOLINOL N-OXIDE
  • 8-HYDROXY-2-METHYLQUINOLINE
  • 8-HYDROXYQUINOLINE-N-OXIDE
  • 8-HYDROXYQUINOLIN-N-OXIDE
  • 2-METHYL-8-HYDROXYQUINOLINE
  • 2-METHYLOXINE
  • OXINE N-OXIDE
  • quinolin-8-ol 1-oxide
  • TIMTEC-BB SBB009099
  • 8-HYDROXYQUINOLINE N-OXIDE 98%
  • NSC 2165
  • 8-HydroxyquinolineN-Oxide&gt
  • 8-Hydroxyquinoline-N-oxide ISO 9001：2015 REACH
  • Procaterol Impurity 38
  • 1127-45-3
  • Building Blocks
  • Alkylquinolines
  • Hydroxyquinolines
  • Quinolines
  • Heterocyclic Building Blocks
  • Quinaldines
  • Quinoline derivatives
  • Quinolines, Isoquinolines & Quinoxalines
  • Quinolines
  • Aromatics Compounds
  • Aromatics
  • Heterocycles
  • Mutagenesis Research Chemicals
  • Quinolines, Isoquinolines & Quinoxalines
  • Morpholines/Thiomorpholines