1H-Imidazole-2-carboxylic acid

Product Name: 1H-Imidazole-2-carboxylic acid
CAS No.: 16042-25-4
Chemical Name: 1H-Imidazole-2-carboxylic acid
Synonyms: IMIDAZOLE-2-CARBOXYLIC ACID;TIMTEC-BB SBB010014;RARECHEM AL BE 0666;2-Carboxy-1H-imidazole;2-Imidazolecarboxylic acid;1H-pyrazole-2-carboxylic acid;1H-Imidazol-2-carboxylic acid;1H-IMIDAZOLE-2-CARBOXYLIC ACID;2-IMidazolecarboxylic Acid Hydrate;1H-IMIDAZOLE-2-CARBOXYLIC ACID 97%
CBNumber: CB9112690
Molecular Formula: C4H4N2O2
Formula Weight: 112.09
MOL File: 16042-25-4.mol

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1H-Imidazole-2-carboxylic acid Property

Melting point:: 198 °C
Boiling point:: 407.9±28.0 °C(Predicted)
Density: 1.524±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,Store in freezer, under -20°C
form: powder to crystal
pka: 1.44±0.10(Predicted)
color: White to Dark blue
λmax: 247nm(lit.)
BRN: 112615
CAS DataBase Reference: 16042-25-4(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 22-26-36/37/39-36
HazardClass: IRRITANT
HS Code: 2933299090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS019334
Product name: Imidazole-2-carboxylic acid
Purity: Aldrich
Packaging: 100mg
Price: $185
Updated: 2025/07/31

TCI Chemical

Product number: I1008
Product name: 2-Imidazolecarboxylic Acid
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $85
Updated: 2025/07/31

TCI Chemical

Product number: I1008
Product name: 2-Imidazolecarboxylic Acid
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $292
Updated: 2025/07/31

TCI Chemical

Product number: I0867
Product name: 2-Imidazolecarboxylic Acid Hydrate
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $70
Updated: 2021/12/16

TCI Chemical

Product number: I0867
Product name: 2-Imidazolecarboxylic Acid Hydrate
Purity: >98.0%(HPLC)
Packaging: 5g
Price: $244
Updated: 2021/12/16

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1H-Imidazole-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis Reference(s)

The Journal of Organic Chemistry, 60, p. 1090, 1995 DOI: 10.1021/jo00109a052

Synthesis

10111-08-7

16042-25-4

General procedure for the synthesis of imidazole-2-carboxylic acid from 2-imidazolecarboxaldehyde: 30% aqueous H2O2 solution (10 g) was slowly added dropwise to stirred aqueous 2-imidazolecarboxaldehyde (2.88 g, 0.030 mol) solution (10 ml). The reaction was continued at room temperature for 72 hours. After completion of the reaction, water was removed by distillation under reduced pressure at room temperature to give a white crystalline solid. The resulting solid was washed with stirred diethyl ether/water (4:1) mixture to remove residual peroxide. Note: Heating may cause decarboxylation to occur. The yield was 97.5%. Melting point (MP) was 156-158 °C. 1H NMR (400 MHz, D2O): δ 7.56 (2H, s, imidazolium ring-H); 13C NMR (400 MHz, D2O): δ 158.86, 141.02, 120.49 ppm. IR (KBr, cm-1): 3392 (m), 3124 (m), 2861 ( m), 1618 (s), 1502 (m), 1462 (m), 1421 (s), 1388 (s), 1322 (m), 1108 (s), 925 (s), 910 (s), 819 (m), 797 (s), 774 (m). Calculated values for elemental analysis (C4H6N2O3, 130.11): C, 36.92%; H, 4.65%; N, 21.53%. Measured values: C, 37.18%; H, 4.94%; N, 21.47%.

References

[1] Journal of Inorganic Biochemistry, 2015, vol. 145, p. 11 - 18

1H-Imidazole-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-Imidazole-2-carboxylic acid Suppliers

Americas 1 Belgium 2 Canada 1 China 157 Europe 1 France 1 Germany 5 India 9 Japan 3 South Korea 1 Switzerland 1 The Netherlands 3 United Kingdom 9 United States 33 Global 227

P&S Chemicals

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View Lastest Price from 1H-Imidazole-2-carboxylic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1H-Imidazole-2-carboxylic acid 16042-25-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 1H-Imidazole-2-carboxylic acid 16042-25-4
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 1H-Imidazole-2-carboxylic acid 16042-25-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2018-08-06

16042-25-4, 1H-Imidazole-2-carboxylic acidRelated Search:

Imidazole Levamisole hydrochloride Retinoic acid Calcium formate Methyl formate Benzoic acid Folic acid Benzyl benzoate Phthalic acid Levamisole 2,3,4-Trihydroxybenzoic acid Imidazole-2-carboxaldehyde ETHYL 5-PYRIMIDINECARBOXYLATE 98 Imidazol-1-yl-acetic acid Dimethyl 4,5-imidazoledicarboxylate 1H-Imidazol-1-ylacetonitrile ETHYL IMIDAZOLE-2-CARBOXYLATE Methyl 4-imidazolecarboxylate

RARECHEM AL BE 0666

TIMTEC-BB SBB010014

IMIDAZOLE-2-CARBOXYLIC ACID

1H-IMIDAZOLE-2-CARBOXYLIC ACID

1H-IMIDAZOLE-2-CARBOXYLIC ACID 97%

2-Imidazolecarboxylic acid

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1H-pyrazole-2-carboxylic acid

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1H-Imidazole-2-carboxylic acid,2-Imidazolecarboxylic Acid Hydrate,Imidazole-2-carboxylic acid

(1H)-Imidazole-2-carboxylic acid, 95%

1H-Imidazol-2-carboxylic acid

16042-25-4

Carboxylic Acids

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Carboxylic Acids

Imidazoles & Benzimidazoles