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5-Methyl-3(2H)-pyridazinone

Product Name
5-Methyl-3(2H)-pyridazinone
CAS No.
54709-94-3
Chemical Name
5-Methyl-3(2H)-pyridazinone
Synonyms
Nsc300284;5-Methylpyrazinone;5-Methylpyridazin-3-ol;5-Methylpyridazin-3-one;5-Methyl-2H-pyridazin-3-one;5-Methyl-3(2H)-pyridazinone;5-methylpyridazin-3(2H)-one;3(2H)-Pyridazinone, 5-Methyl-;3-Hydroxy-5-methyl-pyridazine;5-Methyl-2H-pyridazin-3-one 98%
CBNumber
CB91177476
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
54709-94-3.mol
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5-Methyl-3(2H)-pyridazinone Property

Melting point:
151-153 °C
Density 
1.22±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
pka
11.50±0.40(Predicted)
Appearance
White to yellow Solid
InChI
InChI=1S/C5H6N2O/c1-4-2-5(8)7-6-3-4/h2-3H,1H3,(H,7,8)
InChIKey
MMDFKVYPOQFQHP-UHFFFAOYSA-N
SMILES
C1(=O)NN=CC(C)=C1
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Safety

Hazard Codes 
Xi
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
M332658
Product name
5-Methyl-3(2H)-pyridazinone
Packaging
1g
Price
$75
Updated
2021/12/16
TRC
Product number
M332658
Product name
5-Methyl-3(2H)-pyridazinone
Packaging
100mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
4H17-1-43
Product name
5-Methyl-2H-pyridazin-3-one
Packaging
10g
Price
$248
Updated
2021/12/16
SynQuest Laboratories
Product number
4H17-1-43
Product name
5-Methyl-2H-pyridazin-3-one
Packaging
5G
Price
$186
Updated
2021/12/16
Matrix Scientific
Product number
070470
Product name
5-Methyl-2H-pyridazin-3-one
Purity
99%
Packaging
5g
Price
$80
Updated
2021/12/16
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5-Methyl-3(2H)-pyridazinone Chemical Properties,Usage,Production

Synthesis

40834-42-2

54709-94-3

5-Hydroxy-4-methyl-5H-furan-2-one (10.0 g, 87.6 mmol) was stirred vigorously with hydrazine hydrate (4.38 g, 87.6 mmol) in tetrahydrofuran for 1.5 hours at room temperature. After observing that the solid started to precipitate, the reaction mixture was heated to 60 °C and kept overnight. Upon completion of the reaction, the crude product was adsorbed on silica gel and purified by column chromatography (eluent: 1:1 EtOAc/dichloromethane solvent mixture of 0 to 10% methanol), resulting in 7.7 g of 5-methyl-3(2H)-pyridazinone in 80% yield. The product was characterized by 1H NMR (300 MHz, CDCl3): δ 11.38 (broad single peak, 1H), 7.66 (single peak, 1H), 6.74 (single peak, 1H), 2.25 (single peak, 3H).

References

[1] Patent: US2007/259860, 2007, A1. Location in patent: Page/Page column 31
[2] Patent: WO2008/41075, 2008, A1. Location in patent: Page/Page column 54
[3] Patent: WO2008/41075, 2008, A1. Location in patent: Page/Page column 54
[4] Journal of Organic Chemistry, 1981, vol. 46, # 24, p. 4889 - 4894
[5] Journal of Organic Chemistry, 1981, vol. 46, # 24, p. 4889 - 4894

5-Methyl-3(2H)-pyridazinone Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Methyl-3(2H)-pyridazinone Suppliers

chemcube
Tel
--
Fax
--
Email
sales@chemcube.eu
Country
Germany
ProdList
4083
Advantage
34
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View Lastest Price from 5-Methyl-3(2H)-pyridazinone manufacturers

Shanghai Rlavie Technology Co ltd
Product
5-Methyl-2H-pyridazin-3-one 54709-94-3
Price
US $0.00-0.00/KG
Min. Order
1g
Purity
98%minHPLC
Supply Ability
100kgs/month
Release date
2021-11-14
Dideu Industries Group Limited
Product
5-Methyl-3(2H)-pyridazinone 54709-94-3
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-11-02
Zhuozhou Wenxi import and Export Co., Ltd
Product
5-Methyl-3(2H)-pyridazinone 54709-94-3
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

54709-94-3, 5-Methyl-3(2H)-pyridazinoneRelated Search:


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