5-Bromo-1,3-dihydrobenzoimidazol-2-one
- Product Name
- 5-Bromo-1,3-dihydrobenzoimidazol-2-one
- CAS No.
- 39513-26-3
- Chemical Name
- 5-Bromo-1,3-dihydrobenzoimidazol-2-one
- Synonyms
- 5-BroMo-2-benziMidazolinone;5-Bromobenzo[d]imidazol-2-one;5-BROMO-1H-BENZO[D]IMIDAZOL-2(3H)-ONE;5-Bromo-1,3-dihyrobenzoimidazol-2-one;5-BROMO-1,3-DIHYDRO-BENZIMIDAZOL-2-ONE;5-BROMO-1,3-DIHYDRO-BENZOIMIDAZOL-2-ONE;5-Bromo-1,3-dihydro-2H-benzimidazol-2-one;5-Bromo-2,3-dihydro-2-oxo-1H-benzimidazole;2H-BenziMidazol-2-one, 5-broMo-1,3-dihydro-;5-bromo-2,3-dihydro-1H-1,3-benzodiazol-2-one
- CBNumber
- CB9126318
- Molecular Formula
- C7H5BrN2O
- Formula Weight
- 213.03
- MOL File
- 39513-26-3.mol
5-Bromo-1,3-dihydrobenzoimidazol-2-one Property
- Melting point:
- 336-337 °C(Solv: acetic acid (64-19-7))
- Boiling point:
- 180.0±19.0 °C(Predicted)
- Density
- 1.728±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 11.18±0.30(Predicted)
- Appearance
- Light brown to gray Solid
- InChI
- InChI=1S/C7H5BrN2O/c8-4-1-2-5-6(3-4)10-7(11)9-5/h1-3H,(H2,9,10,11)
- InChIKey
- VWIGEYVTDXNDHV-UHFFFAOYSA-N
- SMILES
- C1(=O)NC2=CC=C(Br)C=C2N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H332Harmful if inhaled
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B997135
- Product name
- 5-Bromo-1,3-dihydrobenzimidazol-2-one
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B997135
- Product name
- 5-Bromo-1,3-dihydrobenzimidazol-2-one
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- B12232
- Product name
- 5-Bromo-1,3-dihydrobenzoimidazol-2-one
- Packaging
- 500mg
- Price
- $35
- Updated
- 2021/12/16
- Product number
- B12232
- Product name
- 5-Bromo-1,3-dihydrobenzoimidazol-2-one
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- FB51600
- Product name
- 5-Bromo-1,3-dihydro-benzimidazol-2-one
- Packaging
- 250mg
- Price
- $62.5
- Updated
- 2021/12/16
5-Bromo-1,3-dihydrobenzoimidazol-2-one Chemical Properties,Usage,Production
Synthesis
530-62-1
1575-37-7
39513-26-3
2.1A. General procedure for the synthesis of 5-bromo-1,3-dihydrobenzimidazol-2-one: 4.29 g (26.46 mmol) of N,N'-carbonyldiimidazole (CDI) was added to 95 mL of N,N-dimethylformamide (DMF) solution containing 4.5 g (24.05 mmol) of 4-bromobenzene-1,2-diamine. The reaction mixture was stirred at 80 °C for 5 hours. After completion of the reaction, the mixture was poured into water and the precipitate formed was filtered out. The precipitate was washed three times with water and subsequently dried in a circulating air dryer at 60 °C. Yield: 4.6 g (90% of theoretical yield); Molecular formula: C7H5BrN2O (M = 213.03); Calculated value: molecular ion peak (M + H)+: 213/215; Measured value: molecular ion peak (M + H)+: 213/215; Rf-value: 0.5 (silica gel, dichloromethane/methanol = 10:1).
References
[1] Journal of Medicinal Chemistry, 2016, vol. 59, # 15, p. 7188 - 7211
[2] Patent: US2005/267115, 2005, A1. Location in patent: Page/Page column 35
[3] Patent: WO2005/103029, 2005, A1. Location in patent: Page/Page column 75
[4] Journal of Medicinal Chemistry, 2006, vol. 49, # 12, p. 3719 - 3742
[5] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 231
5-Bromo-1,3-dihydrobenzoimidazol-2-one Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-1,3-dihydrobenzoimidazol-2-one Suppliers
- Tel
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- Fax
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- Country
- Germany
- ProdList
- 235
- Advantage
- 46
View Lastest Price from 5-Bromo-1,3-dihydrobenzoimidazol-2-one manufacturers
- Product
- 5-Bromo-1,3-dihydrobenzoimidazol-2-one 39513-26-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KGS
- Release date
- 2020-01-03