1H-Benzimidazole-2-carboxylicacid,methylester(9CI)
- Product Name
- 1H-Benzimidazole-2-carboxylicacid,methylester(9CI)
- CAS No.
- 5805-53-8
- Chemical Name
- 1H-Benzimidazole-2-carboxylicacid,methylester(9CI)
- Synonyms
- Methyl BenziMidazole-2-carboxylate;1H-benzimidazole-2-methyl carboxylate;methyl 1H-1,3-benzodiazole-2-carboxylate;2-Benzimidazolecarboxylic acid, methyl ester;1H-Benzimidazole-2-carboxylicacid,methylester(9CI)
- CBNumber
- CB91291969
- Molecular Formula
- C9H8N2O2
- Formula Weight
- 176.17
- MOL File
- 5805-53-8.mol
1H-Benzimidazole-2-carboxylicacid,methylester(9CI) Property
- Melting point:
- 187.3 °C
- Boiling point:
- 343.1±25.0 °C(Predicted)
- Density
- 1.324±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 10.39±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChI
- InChI=1S/C9H8N2O2/c1-13-9(12)8-10-6-4-2-3-5-7(6)11-8/h2-5H,1H3,(H,10,11)
- InChIKey
- LKUBWDNDGBVKFK-UHFFFAOYSA-N
- SMILES
- C1(C(OC)=O)NC2=CC=CC=C2N=1
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- M219795
- Product name
- Methyl1H-Benzo[d]imidazole-2-carboxylate
- Packaging
- 500mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- OR480814
- Product name
- 1H-Benzimidazole-2-carboxylicacidmethylester
- Purity
- 95%
- Packaging
- 1g
- Price
- $170
- Updated
- 2021/12/16
- Product number
- W7131
- Product name
- Methyl1H-benzo[d]imidazole-2-carboxylate
- Packaging
- 250mg
- Price
- $89
- Updated
- 2021/12/16
- Product number
- W7131
- Product name
- Methyl1H-benzo[d]imidazole-2-carboxylate
- Packaging
- 5g
- Price
- $300
- Updated
- 2021/12/16
- Product number
- W7131
- Product name
- Methyl1H-benzo[d]imidazole-2-carboxylate
- Packaging
- 10g
- Price
- $474
- Updated
- 2021/12/16
1H-Benzimidazole-2-carboxylicacid,methylester(9CI) Chemical Properties,Usage,Production
Synthesis
67-56-1
3584-65-4
5805-53-8
General procedure for the synthesis of methyl 1H-benzimidazole-2-carboxylate from methanol and 2-(trichloromethyl)-1H-benzo[d]imidazole: Sodium carbonate (Na2CO3, 0.64 g, 6.07 mmol) was added to a solution of 2-(trichloromethyl)-1H-benzo[d]imidazole (1.9 g, 6.07 mmol) in methanol (20 mL). The reaction mixture was heated to reflux for 14 h and subsequently cooled to room temperature. 1N hydrochloric acid (HCl) was added to the reaction solution and stirred for 0.5 hr. The reaction mixture was extracted with ethyl acetate (EA). The organic phase was washed with saturated brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure to give methyl 1H-benzimidazole-2-carboxylate (0.89 g, yield not stated). Mass spectrometry (MS) analysis showed the molecular ion peak (M+1) to be 177, which was consistent with the theoretically calculated value (C9H8N2O2, 176).
References
[1] Patent: WO2011/143365, 2011, A1. Location in patent: Page/Page column 138
[2] Patent: WO2008/33739, 2008, A2. Location in patent: Page/Page column 31
1H-Benzimidazole-2-carboxylicacid,methylester(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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