3-Pyridinemethanamine,6-fluoro-(9CI)
- Product Name
- 3-Pyridinemethanamine,6-fluoro-(9CI)
- CAS No.
- 205744-17-8
- Chemical Name
- 3-Pyridinemethanamine,6-fluoro-(9CI)
- Synonyms
- (6-Fluoropyridin-3-yl);2-fluoro-5-pyridylmethylamine;6-Fluoro-3-pyridineMethanaMine;3-Pyridinemethanamine, 6-fluoro-;3-(Aminomethyl)-6-fluoropyridine;2-fluoro-5-(aminomethyl)pyridine;5-(Aminomethyl)-2-fluoropyridine;3-Pyridinemethanamine,6-fluoro-(9CI)
- CBNumber
- CB91300803
- Molecular Formula
- C6H7FN2
- Formula Weight
- 126.13
- MOL File
- 205744-17-8.mol
3-Pyridinemethanamine,6-fluoro-(9CI) Property
- Boiling point:
- 63-65 °C(Press: 0.56 Torr)
- Density
- 1.180±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 7.73±0.29(Predicted)
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C6H7FN2/c7-6-2-1-5(3-8)4-9-6/h1-2,4H,3,8H2
- InChIKey
- KYRWSLUCAPNJPI-UHFFFAOYSA-N
- SMILES
- C1=NC(F)=CC=C1CN
Safety
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- F598268
- Product name
- 6-Fluoro-3-pyridinemethanamine
- Packaging
- 100mg
- Price
- $110
- Updated
- 2021/12/16
- Product number
- PC403115
- Product name
- (6-Fluoropyridin-3-yl)methylamine
- Packaging
- 250mg
- Price
- $99
- Updated
- 2021/12/16
- Product number
- 3H30-3-3V
- Product name
- (6-Fluoropyridin-3-yl)methanamine
- Packaging
- 250mg
- Price
- $159
- Updated
- 2021/12/16
- Product number
- PC403115
- Product name
- (6-Fluoropyridin-3-yl)methylamine
- Packaging
- 1g
- Price
- $247
- Updated
- 2021/12/16
- Product number
- 3H30-3-3V
- Product name
- (6-Fluoropyridin-3-yl)methanamine
- Packaging
- 1g
- Price
- $396
- Updated
- 2021/12/16
3-Pyridinemethanamine,6-fluoro-(9CI) Chemical Properties,Usage,Production
Uses
6-Fluoro-3-pyridinemethanamine is a useful compound for the study of herbicidal activity of 2-cyano-3-[[(6-fluoro-3-pyridinyl)methyl]amino]acrylates.
Synthesis
3939-12-6
205744-17-8
General procedure for the synthesis of (6-fluoropyridin-3-yl)methanamine from 6-fluoro-3-cyanopyridine: 6-fluoro-3-cyanopyridine (300 mg, 2.46 mmol) was dissolved in 2 mol/L ammonia/methanol solution (30 mL), nickel Ruanne (0.5 g) was added at room temperature and the reaction was carried out for 12 h under hydrogen atmosphere. Upon completion of the reaction, the reaction mixture was filtered through diatomaceous earth and washed with methanol (5 mL x 2). The filtrate was concentrated to dryness and the residue was purified by silica gel column chromatography (eluent ratio of dichloromethane: methanol = 100:4) to give 262 mg of yellow oily solid in 85% yield.
References
[1] Patent: CN106916101, 2017, A. Location in patent: Paragraph 0149; 0150
[2] Journal of Medicinal Chemistry, 2017, vol. 60, # 19, p. 7965 - 7983
3-Pyridinemethanamine,6-fluoro-(9CI) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-Pyridinemethanamine,6-fluoro-(9CI) manufacturers
- Product
- 3-Pyridinemethanamine,6-fluoro-(9CI) 205744-17-8
- Price
- US $2.00/KG
- Min. Order
- 1g
- Purity
- 98%min
- Supply Ability
- ask
- Release date
- 2020-01-08