2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile

Product Name: 2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile
CAS No.: 763114-25-6
Chemical Name: 2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile
Synonyms: (Z)-2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)Methyl)benzonitrile;2-Fluoro-5-(3-oxo-3H-isobenzofuran-1-ylidenemethyl)-benzonitrile;2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)Methyl)benzonitrile;2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzonitrile;Olaparib Impurity 76;2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)meth;2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzoni;2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]benzoni...;2-Fluoro-5- (3-oxo-1 (3H) - isobenzofuran) methyl] benzonitrile;2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile
CBNumber: CB52506451
Molecular Formula: C16H8FNO2
Formula Weight: 265.24
MOL File: 763114-25-6.mol

More

Less

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Property

Boiling point:: 430.1±45.0 °C(Predicted)
Density: 1.38
storage temp.: Sealed in dry,Room Temperature
solubility: Dichloromethane, Tetrahydrofuran
form: Solid
color: White
InChI: InChI=1S/C16H8FNO2/c17-14-6-5-10(7-11(14)9-18)8-15-12-3-1-2-4-13(12)16(19)20-15/h1-8H
InChIKey: MMPHWTMMVPBHRZ-UHFFFAOYSA-N
SMILES: C(#N)C1=CC(C=C2C3=C(C=CC=C3)C(=O)O2)=CC=C1F

More

Less

Safety

HS Code: 2932990090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: F595100
Product name: 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile
Packaging: 2.5g
Price: $1320
Updated: 2021/12/16

Apolloscientific

Product number: PC51400
Product name: 2-Fluoro-5-(3-oxo-3H-isobenzofuran-1-ylidenemethyl)-benzonitrile
Purity: 97%
Packaging: 25g
Price: $402
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0416676
Product name: 2-FLUORO-5-[(3-OXO-1(3H)-ISOBENZOFURANYLIDENE)METHYL]-BENZONITRILE
Purity: 95.00%
Packaging: 5MG
Price: $503.9
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 58170
Product name: 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile
Packaging: 250mg
Price: $650
Updated: 2021/12/16

Matrix Scientific

Product number: 096539
Product name: 2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile
Purity: 95+%
Packaging: 1g
Price: $706
Updated: 2021/12/16

More

Less

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile is intermediate in the preparation of poly (ADP-ribose) polymerase (PARP) inhibitors. Olaparib intermediate.

Synthesis

(3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphonic acid (5.00 g, 0.021 mol) in tetrahydrofuran (30 mL) was added to a 150 mL round-bottom flask. To this solution, triethylamine(5.6 mL, 0.042 mol) was added. 2-Fluoro-5-formyl benzonitrile( 3.08 g, 0.021 mol) was dissolved in tetrahydrofuran into another round-bottom flask, followed by adding triethylamine (2.9 mL, 0.021 mol) and stirring evenly. Then the reaction fluids in the two flasks were mixed and reacted at room temperature for 12 h. The product was concentrated under reduced pressure and 50 mL of water was added. The suspension was stirred for 30 min until the solids were not precipitated. Finally, filtration was performed, and the filter cake was collected and dried to obtain 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile(5.41 g, 97%).

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile Suppliers

Canada 1 China 209 Germany 1 India 5 United Kingdom 1 United States 6 Global 223

Shanghai Boc Chemical Co.,Ltd

Tel: 021-34975603-808 18721111801
Fax: +86-21-34975602-805
Email: sales@bocpharma.com
Country: China
ProdList: 998
Advantage: 64

Hunan Eurasian Pharmaceutical Co. Ltd.

Tel: 0592-5789919 13328776692
Email: 2851802016@qq.com
Country: China
ProdList: 80
Advantage: 58

Hangzhou Chemtrue Bio-Tech Co.,Ltd.

Tel: 0571-86828652 18857119830
Fax: 0571-83522824
Email: sales@chemtrue-bio.com
Country: China
ProdList: 326
Advantage: 58

Hangzhou Read Chemical Co., Ltd

Tel: 15306818081 15306818081
Fax: 0571-87234255
Email: sales@hzread.com
Country: China
ProdList: 61
Advantage: 58

Tianjin Branch Chong pharmaceutical intermediates Co., Ltd.

Tel: 022-60116533 13207668525
Fax: 022-60979672
Email: saleskc@scipharmacn.com
Country: China
ProdList: 683
Advantage: 58

Jinan Dexinjia Bio&Tech Co., Ltd

Tel: 0531-82375886 13001715031
Fax: 0531-82375893
Email: 3517280075@qq.com
Country: China
ProdList: 1322
Advantage: 58

Shandong Xuande Pharmaceutical Technology Co. LTD

Tel: 18866895588
Fax: 0531-82777287
Email: dingjiaying@shiningpharm.com
Country: China
ProdList: 96
Advantage: 55

TIANJIN PHARMACN MEDICAL TECHNOLOGY CO.,LTD.

Tel: 022-60182192,1339732154 18722583064
Fax: 86-22-60979672
Email: marketing@pharmacn.com
Country: China
ProdList: 112
Advantage: 61

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94657
Advantage: 76

Yangzhou Siyu Chemical Co.,Ltd.

Tel: 0514-87325867
Fax: 0086-514-87325867
Email: sales@siyuchem.com
Country: China
ProdList: 370
Advantage: 55

More

Less

View Lastest Price from 2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile manufacturers

Nanjing Fred Technology Co., Ltd

Product: 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile 763114-25-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1 ton
Release date: 2023-12-27

Henan Fengda Chemical Co., Ltd

Product: 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile 763114-25-6
Price: US $5.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-16

Changzhou Rokechem Technology Co., Ltd.

Product: 2-Fluoro-5-[(3-oxo-1(3H)- isobenzofuranylidene)methyl]-benzonitrile 763114-25-6
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99%，USP/CP/EP
Supply Ability: 1-10000kgs
Release date: 2023-06-08

763114-25-6, 2-Fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrileRelated Search:

2-FLUORO-5-METHYLPYRIDINE-3-BORONIC ACID PINACOL ESTER 3-Pyridinemethanamine,6-fluoro-(9CI) Pyridine, 2-fluoro-5-methoxy- (9CI) 2-Fluoro-5-iodobenzonitrile 5-BROMO-2-FLUORONICOTINIC ACID 2-Fluoro-5-iodonitrobenzene 2-Fluoro-5-Iodoaniline 2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoic acid 2-Fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzonitrile tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)benzoyl)piperazine-1-carboxylate 1-(CYCLOPROPANECARBONYL)PIPERAZINE 97 3-oxo-1,3-dihydroisobenzofuran-1-ylphosphonic acid Piperazine, 1-(cyclopropylcarbonyl)-, Monohydrochloride Olaparib Ethanol 1-[2-[4-Hydroxy-3-(2-hydroxyethyl)phenyl]ethyl]-α,α-diphenyl- Dafina new intermediate Obeticholic acid related substance A

2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile

(Z)-2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)Methyl)benzonitrile

2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)Methyl)benzonitrile

2-Fluoro-5-(3-oxo-3H-isobenzofuran-1-ylidenemethyl)-benzonitrile

2-fluoro-5-(3-oxo-1,3-dihydroisobenzofuranylidene methyl)benzonitrile

(E)-2-fluoro-5-((3-oxoisobenzofuran-1(3H)-ylidene)methyl)benzonitrile

2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzonitrile

Benzonitrile, 2-fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-

2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)meth

2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]benzoni...

2-fluoro-5-[(3-oxo-1,3-dihydro-2-benzofuran-1-ylidene)methyl]benzonitrile

C16H8FNO2 2-Fluoro-5-[(3-oxo-1(3H)-isobenzofuranylidene)methyl]-benzonitrile 763114-25-6

Olaparib Impurity 76

2- Fluoro-5-[(3-oxo-1(3H)-isobenzo-furanylidene)-methyI]I- benzonitrile

2-Fluoro-5- (3-oxo-1 (3H) - isobenzofuran) methyl] benzonitrile

2-fluoro-5-[(Z)-(3-oxo-2-benzofuran-1-ylidene)methyl]benzoni

763114-25-6

C16H8FNO2

trebectedin

1