(1'S,2'S)-NICOTINE 1'-OXIDE
- Product Name
- (1'S,2'S)-NICOTINE 1'-OXIDE
- CAS No.
- 51095-86-4
- Chemical Name
- (1'S,2'S)-NICOTINE 1'-OXIDE
- Synonyms
- S,2’Nicotine Impurity 1;S)-Nicotine-1’Nicotine-cis-N-oxide;(1's2's)-Nicotine-N'-oxide;(1'S,2'S)-NICOTINE 1'-OXIDE;(1S,2S)-syn-Nicotine N'-oxide;(1'S,2'S)-TRANS-NICOTINE 1'-OXIDE;(1'S,2'S)-trans-Nicotine-1'-N-oxide;3-[(1S,2S)-1-Methyl-1-oxido-2-pyrrolidinyl]
- CBNumber
- CB9131437
- Molecular Formula
- C10H14N2O
- Formula Weight
- 178.23
- MOL File
- Mol file
(1'S,2'S)-NICOTINE 1'-OXIDE Property
- Melting point:
- 182-183°C
- storage temp.
- Hygroscopic, -20°C Freezer, Under Inert Atmosphere
- solubility
- DMF: 50 mg/ml; DMSO: 30 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml
- form
- A crystalline solid
- pka
- 4.63±0.40(Predicted)
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H331Toxic if inhaled
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P311Call a POISON CENTER or doctor/physician.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P322Specific measures (see …on this label).
P330Rinse mouth.
P361Remove/Take off immediately all contaminated clothing.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 16413
- Product name
- (1'S,2'S)-Nicotine-1'-oxide
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- 16413
- Product name
- (1'S,2'S)-Nicotine-1'-oxide
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $176
- Updated
- 2024/03/01
- Product number
- 16413
- Product name
- (1'S,2'S)-Nicotine-1'-oxide
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $330
- Updated
- 2024/03/01
- Product number
- N427500
- Product name
- (1’S,2’S)-Nicotine1’-Oxide
- Packaging
- 250mg
- Price
- $490
- Updated
- 2021/12/16
- Product number
- N427500
- Product name
- (1’S,2’S)-Nicotine1’-Oxide
- Packaging
- 100mg
- Price
- $180
- Updated
- 2021/12/16
(1'S,2'S)-NICOTINE 1'-OXIDE Chemical Properties,Usage,Production
Chemical Properties
Off-White to Yellow Solid
Uses
Nicotine-1’-N-oxide is a derivative of Nicotine (N412420) found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine in man proceeds by alternative routes of oxidation of nitrogen to form nicotine-1’-N-oxide (both diastereomers) or cotinine. The ratio of these two products has been suggested as an indicator of bladder cancer in humans.
Uses
Nicotine-1’-N-oxide is a derivative of nicotine found in the leaves, stems, and roots of N. tabacum, N. affinis and N. sylvestris. Nicotine-1’-N-oxide has also been identified as a metabolite of nicotine in animals and in man. The metabolism of nicotine
Definition
ChEBI: Trans-(S)-nicotine N(1')-oxide is an (S)-nicotine N(1')-oxide in which the N(1')-methyl group is on the opposite side of the pyrrolidine ring to the pyridine substituent. The major species at pH 7.3.