Levocetirizine dihydrochloride

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Levocetirizine dihydrochloride

Product Name: Levocetirizine dihydrochloride
CAS No.: 130018-87-0
Chemical Name: Levocetirizine dihydrochloride
Synonyms: DDDB;LevocetrizineHCl;LEVOCETIRIZINE HCL;Levocetirizine HCI;LEVOCETIRIZINE 2HCL;Levocitirizine 2HCL;LEVOCETIRIZINE DIHCL;(R)-Cetirizine DiHCl;Xyzal Dihydrochloride;(R)-Form dihydrochloride
CBNumber: CB9135031
Molecular Formula: C21H27Cl3N2O3
Formula Weight: 461.81
MOL File: 130018-87-0.mol

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Levocetirizine dihydrochloride Property

Melting point:: 215-220°C
alpha: D25 -12.79° (c = 1 in water)
storage temp.: room temp
solubility: H2O: ≥23mg/mL
form: powder
color: White to Almost white
Merck: 14,2022
Stability:: Hygroscopic
CAS DataBase Reference: 130018-87-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-50/53
Safety Statements: 60-61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
RTECS: AG0990000
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L7795
Product name: Levocetirizine dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 10mg
Price: $97.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: L7795
Product name: Levocetirizine dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 50mg
Price: $376
Updated: 2024/03/01

TCI Chemical

Product number: L0264
Product name: Levocetirizine Dihydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $101
Updated: 2024/03/01

TCI Chemical

Product number: L0264
Product name: Levocetirizine Dihydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $304
Updated: 2024/03/01

Cayman Chemical

Product number: 23992
Product name: (R)-Cetirizine (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $68
Updated: 2024/03/01

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Levocetirizine dihydrochloride Chemical Properties,Usage,Production

Uses

Anti Histaminic

Uses

Levocetirizine dihydrochloride has been used as standard in the thin layer chromatography optimization and in preparation of racemic cetirizine standard for subcritical fluid chromatography-tandem mass spectrometry analysis.

General Description

Levocetirizine dihydrochloride,(R)-[2-[4-[(4-chlorophenyl) phenylmethyl]-1-piperazinyl] ethoxy] acetic acid dihydrochloride, (Xyzal) is awhite, crystalline powder and is water soluble. ThisR-enantiomer is has a 30-fold higher affinity than the S-enantiomer,and dissociates more slowly from H₁-receptors.Pharmacologically, it displays the same receptor and CNSselecitivity profile as the racemate, cetirizine,and thus the same therapeutic advantages. Levocetirizine isindicated for the relief of symptoms associated with allergicrhinitis (seasonal and perennial) in adults and children 6 yearsof age and older and for the treatment of the uncomplicatedskin manifestations of chronic idiopathic urticaria in adultsand children 6 years of age and older. Its pharmacokineticsand clearance profile are essentially the same as the racemate,cetirizine .

Biochem/physiol Actions

Levocetirizine hydrochloride is a nonsedating antihistamine. It is a histamine H1-receptor antagonist, the active isomer of cetirizine. Levocetirizine has high bioavailability, high affinity for and occupancy of the H1 receptor.

Levocetirizine dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Levocetirizine dihydrochloride manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Levocetirizine dihydrochloride 130018-87-0
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-04-24

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Levocetirizine dihydrochloride 130018-87-0
Price: US $0.00/Kg/Bag
Min. Order: 1KG
Purity: 98.0%~102.0%; USP41
Supply Ability: 1500kg/month
Release date: 2021-06-03

airuikechemical co., ltd.

Product: Levocetirizine dihydrochloride 130018-87-0
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 20tons
Release date: 2024-04-07

130018-87-0, Levocetirizine dihydrochlorideRelated Search:

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LEVOCETIRIZINE 2HCL

LEVOCETIRIZINE DIHCL

LEVOCETIRIZINE DIHYDROCHLORIDE

LEVOCETIRIZINE HCL

LEVOCETRIZINE DIHYDROCHLORIDE

[2-[4-[(r)-(4-chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride

[2-[4-[(R)-(4-CHLOROPHENYL)PHENYLMETHYL]-1-PIPERAZINYL]ETHOXY]-ACETIC ACID 2HCL

(R)-Cetirizine (hydrochloride)

LevocetrizineHCl

LEVOCITIRIZINE DIHYDROCHLORIDE

(R) -2-[2-[4-[(4-Chlorophenyl) phenylmethyl] piperazin-1-yl]ethoxy]acetic acid dihydrochloride

(2-(4-[(R)-(4-Chlorophenyl)(phenyl)methyl]piperazin-1-yl)ethoxy)acetic acid dihydrochloride

Levocitirizine 2HCL

(R)-Cetirizine diHCl (Levocetirizine diHCl)

Levocetirizine dihydrochloride [2-[4-[(R)-(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]-acetic acid dihydrochloride

2-[2-[4-[(R)-(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride

DDDB

Cetirizine hydrochloride sinistral

(R)-Form dihydrochloride

LEVOCETIRIZINE;(R)-CETIRIZINE (HYDROCHLORIDE)

LevocetirizineDihydrochloride&gt

Levocetirizine Dihydrochlorid

Levocetirizine dihydrochloride USP/EP/BP

Levocetirizine Hydrochloride Impurities

Levocetirizine Dihydrochloride Powder

Levocetirizine D4 DihydrochlorideQ: What is Levocetirizine D4 Dihydrochloride Q: What is the CAS Number of Levocetirizine D4 Dihydrochloride Q: What is the storage condition of Levocetirizine D4 Dihydrochloride

Levocetirizine DihydrochlorideQ: What is Levocetirizine Dihydrochloride Q: What is the CAS Number of Levocetirizine Dihydrochloride Q: What is the storage condition of Levocetirizine Dihydrochloride

Levocetirizine Dihydrochloride (1359969)

(-)-Cetirizine Dihydrochloride

Xyzal Dihydrochloride

(R)-Cetirizine DiHCl

Levocetirizine HCI

LEVOCETIRIZINE HYDROCHLORIDE IP

Levocetirizine Dihydrochloride, ≥ 98.0%

Levocetirizine Dihydrochloride -IHS/IPS

Levocetirizine dihydrochloride IMpurity

130018-87-0

3008-87-0

C21H25ClN2O32ClH

Antibiotics

Levocitirizine 2HCl

API

Histamine receptor

API's

Levocetirizine