ChemicalBook > CAS DataBase List > Ropinirole

Ropinirole

Product Name
Ropinirole
CAS No.
91374-21-9
Chemical Name
Ropinirole
Synonyms
Ropinirole base;SKF-101468;ROPINIROLE;Ropinirolum;ROPINIROLE 99%;RSYYRopinirole;Unii-030pyr8953;SKF-101468A：ReQuip;Ropinirole USP/EP/BP;Ropinirole Impurity 22
CBNumber
CB9137570
Molecular Formula
C16H24N2O
Formula Weight
260.37
MOL File
91374-21-9.mol
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Ropinirole Property

Melting point:
243-250°C
Boiling point:
410.5±45.0 °C(Predicted)
Density 
1.040±0.06 g/cm3(Predicted)
pka
14.17±0.20(Predicted)
CAS DataBase Reference
91374-21-9(CAS DataBase Reference)
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Safety

Hazardous Substances Data
91374-21-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
3680
Product name
Ropinirole
Purity
≥99%(HPLC)
Packaging
10
Price
$87
Updated
2021/12/16
Tocris
Product number
3680
Product name
Ropinirole
Purity
≥99%(HPLC)
Packaging
50
Price
$363
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004095
Product name
ROPINIROLE
Purity
95.00%
Packaging
10MG
Price
$612.44
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D34162
Product name
Ropinirole-d14 HCl
Packaging
1mg
Price
$625
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004095
Product name
ROPINIROLE
Purity
95.00%
Packaging
50MG
Price
$823.46
Updated
2021/12/16
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Ropinirole Chemical Properties,Usage,Production

Uses

Antiparkinsonian (D2receptor agonist).

Definition

ChEBI: Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent.

brand name

Requip (GlaxoSmithKline).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028

Clinical Use


Anti-Parkinson agent
Restless legs syndrome (RLS)

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian effect - avoid.
Oestrogens: concentration increased.

Metabolism

Ropinirole is hepatically metabolised by the cytochrome P450 enzyme, CYP1A2, and excreted in the urine as inactive metabolites.

Ropinirole Preparation Products And Raw materials

Raw materials

Tetrazole Indole

Preparation Products

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Ropinirole Suppliers

Canada 2 China 111 Europe 2 Germany 1 India 10 The Netherlands 1 United Kingdom 3 United States 21 Global 151
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Suzhou Kaiyuan Minsheng Sci&Tech Corp. Ltd.
Tel
0512-62889106
Fax
0512-62889106
Email
business@minshengpharm.com
Country
China
ProdList
110
Advantage
66
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2127
Advantage
70
Hunan Hui Bai Shi Biotechnology Co., Ltd.
Tel
0731-85526065 13308475853
Email
ivy@hnhbsj.com
Country
China
ProdList
4550
Advantage
62
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2893
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
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View Lastest Price from Ropinirole manufacturers

Hebei Mingeng Biotechnology Co., Ltd
Product
Ropinirole 91374-21-9
Price
US $200.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg/Month
Release date
2022-11-27
Shijiazhuang Gantuo Biotechnology Co., Ltd
Product
Ropinirole 91374-21-9
Price
US $100.00/mg
Min. Order
25mg
Purity
99%
Supply Ability
1000g
Release date
2023-03-10
Baoji Guokang Healthchem co.,ltd
Product
Ropinirole
Price
US $64.00/g
Min. Order
1g
Purity
99%
Supply Ability
10kg
Release date
2021-06-07

91374-21-9, RopiniroleRelated Search:

Tetraethylammonium hydroxide cis-Octahydro-isoindole Nile Red 1-(2,6-Dichlorophenyl)indolin-2-one ROPINIROLE HYDROCHLORIDE,ROPINIROLE HCL Ropinirole Intermediate 3 Ropinirole Intermediate 6 4-(2-BroMoethyl)-1,3-dihydro-2H-indolin-2-one Ropinirole Intermediate 1 2-Butanone Ropinirole Intermediate 5 ROPINIROLE-D3, HYDROCHLORIDE 3-Oxo Ropinirole (Ropinirole Impurity C),Ropinirole Impurity C N-Despropyl Ropinirole-d3 Discontinued see product # D297382,N-Despropyl Ropinirole-d3 N-PROPYL-D7-AMINE N-Despropyl Ropinirole Discontinued see product # D297380,N-DESPROPYL ROPINIROLE DI-N-PROPYL-1,1,2,2,3,3,3-D7-AMINE (MONO-PROPYL-D7) Ropinirole

  • ROPINIROLE
  • 4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one
  • ROPINIROLE: ROPINIROLE HYDROCHLORIDE
  • ROPINIROLE INTERMEIDATES:
  • ROPINIROLE 99%
  • 4-[2-(Dipropylamino)ethyl]-1，3-dihydrcr2H-indol-2-one
  • SKF-101468
  • SKF-101468A：ReQuip
  • 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one
  • 4-[2-(Dipropylamino)ethyl]indoline-2-one
  • 2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-
  • 91374-20-8 (Hydrochloride)
  • Ropinirol [inn-spanish]
  • Ropinirolum
  • Ropinirolum [inn-latin]
  • Unii-030pyr8953
  • Ropinirole base
  • Ropinirole(Hydrochloride form)
  • (3S)-3-bromo-2-oxobutanoic acid
  • Ropinirole USP/EP/BP
  • Ropinirole Impurity 22
  • Ropinirole Impurity 23
  • Ropinirole Impurity 24
  • 4-(2-(Dipropylamino)ethyl)indolin-2-one
  • Ropinirole (SKF-101468)
  • RSYYRopinirole
  • RSYYIbrutinib Impurity 141
  • 91374-21-9
  • 91374-58-8
  • C16H24N2O
  • API
  • ACTIVE PHARMACEUTICAL INGREDIENTS
  • Pharmaceutical material and intermeidates
  • Antiparkinsonian