ChemicalBook > CAS DataBase List > Ropinirole

Ropinirole

Product Name: Ropinirole
CAS No.: 91374-21-9
Chemical Name: Ropinirole
Synonyms: Ropinirole base;SKF-101468;ROPINIROLE;Ropinirolum;ROPINIROLE 99%;RSYYRopinirole;Unii-030pyr8953;SKF-101468A：ReQuip;Ropinirole USP/EP/BP;Ropinirole Impurity 22
CBNumber: CB9137570
Molecular Formula: C16H24N2O
Formula Weight: 260.37
MOL File: 91374-21-9.mol

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Ropinirole Property

Melting point:: 243-250°C
Boiling point:: 410.5±45.0 °C(Predicted)
Density: 1.040±0.06 g/cm3(Predicted)
pka: 14.17±0.20(Predicted)
CAS DataBase Reference: 91374-21-9(CAS DataBase Reference)

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Safety

Hazardous Substances Data: 91374-21-9(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 3680
Product name: Ropinirole
Purity: ≥99%(HPLC)
Packaging: 10
Price: $87
Updated: 2021/12/16

Tocris

Product number: 3680
Product name: Ropinirole
Purity: ≥99%(HPLC)
Packaging: 50
Price: $363
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004095
Product name: ROPINIROLE
Purity: 95.00%
Packaging: 10MG
Price: $612.44
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: D34162
Product name: Ropinirole-d14 HCl
Packaging: 1mg
Price: $625
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004095
Product name: ROPINIROLE
Purity: 95.00%
Packaging: 50MG
Price: $823.46
Updated: 2021/12/16

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Ropinirole Chemical Properties,Usage,Production

Chemical Properties

Ropinirole Hydrochloride: C16H24N2O·HCl. [91374-20-8]. Crystallized from acetonitrile, melting point 241-243°C.

Uses

Antiparkinsonian (D2receptor agonist).

Definition

ChEBI: Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent.

brand name

Requip (GlaxoSmithKline).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028

Clinical Use

Anti-Parkinson agent
Restless legs syndrome (RLS)

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian effect - avoid.
Oestrogens: concentration increased.

Metabolism

Ropinirole is hepatically metabolised by the cytochrome P450 enzyme, CYP1A2, and excreted in the urine as inactive metabolites.

Ropinirole Preparation Products And Raw materials

Raw materials

Tetrazole Indole

Preparation Products

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View Lastest Price from Ropinirole manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Ropinirole 91374-21-9
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1KG 100KG 1MT
Release date: 2025-05-20

Fuzhou Lista Biotechnology Co.,Ltd

Product: Ropinirole 91374-21-9
Price: US $90.00-80.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 2000kg
Release date: 2024-08-12

Hebei Mingeng Biotechnology Co., Ltd

Product: Ropinirole 91374-21-9
Price: US $200.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg/Month
Release date: 2022-11-27

91374-21-9, RopiniroleRelated Search:

Tetraethylammonium hydroxide cis-Octahydro-isoindole Nile Red 1-(2,6-Dichlorophenyl)-2-hydroindole ROPINIROLE HYDROCHLORIDE,ROPINIROLE HCL Ropinirole Intermediate 3 Ropinirole Intermediate 6 4-(2-BroMoethyl)-1,3-dihydro-2H-indolin-2-one Ropinirole Intermediate 5 Ropinirole Intermediate 1 2-Butanone ROPINIROLE-D3, HYDROCHLORIDE 3-Oxo Ropinirole (Ropinirole Impurity C),Ropinirole Impurity C N-Despropyl Ropinirole-d3Discontinued see product # D297382,N-Despropyl Ropinirole-d3 N-PROPYL-D7-AMINE N-Despropyl RopiniroleDiscontinued see product # D297380,N-DESPROPYL ROPINIROLE DI-N-PROPYL-1,1,2,2,3,3,3-D7-AMINE (MONO-PROPYL-D7) Ropinirole

ROPINIROLE

4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one

ROPINIROLE: ROPINIROLE HYDROCHLORIDE

ROPINIROLE INTERMEIDATES:

ROPINIROLE 99%

4-[2-(Dipropylamino)ethyl]-1，3-dihydrcr2H-indol-2-one

SKF-101468

SKF-101468A：ReQuip

4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one

4-[2-(Dipropylamino)ethyl]indoline-2-one

2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-

91374-20-8 (Hydrochloride)

Ropinirol [inn-spanish]

Ropinirolum

Ropinirolum [inn-latin]

Unii-030pyr8953

Ropinirole base

Ropinirole(Hydrochloride form)

(3S)-3-bromo-2-oxobutanoic acid

Ropinirole USP/EP/BP

Ropinirole Impurity 22

Ropinirole Impurity 23

Ropinirole Impurity 24

4-(2-(Dipropylamino)ethyl)indolin-2-one

Ropinirole (SKF-101468)

RSYYRopinirole

RSYYIbrutinib Impurity 141

91374-21-9

91374-58-8

C16H24N2O

API

ACTIVE PHARMACEUTICAL INGREDIENTS

Pharmaceutical material and intermeidates

Antiparkinsonian