Ropinirole

ChemicalBook > CAS DataBase List > Ropinirole

Product Name: Ropinirole
CAS No.: 91374-21-9
Chemical Name: Ropinirole
Synonyms: Ropinirole base;SKF-101468;ROPINIROLE;Ropinirolum;ROPINIROLE 99%;RSYYRopinirole;Unii-030pyr8953;SKF-101468A：ReQuip;Ropinirole USP/EP/BP;Ropinirole Impurity 22
CBNumber: CB9137570
Molecular Formula: C16H24N2O
Formula Weight: 260.37
MOL File: 91374-21-9.mol

Less

Ropinirole Property

Melting point:: 243-250°C
Boiling point:: 410.5±45.0 °C(Predicted)
Density: 1.040±0.06 g/cm3(Predicted)
pka: 14.17±0.20(Predicted)
CAS DataBase Reference: 91374-21-9(CAS DataBase Reference)

Less

Safety

Hazardous Substances Data: 91374-21-9(Hazardous Substances Data)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Tocris

Product number: 3680
Product name: Ropinirole
Purity: ≥99%(HPLC)
Packaging: 10
Price: $87
Updated: 2021/12/16

Tocris

Product number: 3680
Product name: Ropinirole
Purity: ≥99%(HPLC)
Packaging: 50
Price: $363
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004095
Product name: ROPINIROLE
Purity: 95.00%
Packaging: 10MG
Price: $612.44
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: D34162
Product name: Ropinirole-d14 HCl
Packaging: 1mg
Price: $625
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004095
Product name: ROPINIROLE
Purity: 95.00%
Packaging: 50MG
Price: $823.46
Updated: 2021/12/16

Less

Ropinirole Chemical Properties,Usage,Production

Uses

Antiparkinsonian (D2receptor agonist).

Definition

ChEBI: Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent.

brand name

Requip (GlaxoSmithKline).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028

Clinical Use

Anti-Parkinson agent
Restless legs syndrome (RLS)

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian effect - avoid.
Oestrogens: concentration increased.

Metabolism

Ropinirole is hepatically metabolised by the cytochrome P450 enzyme, CYP1A2, and excreted in the urine as inactive metabolites.

Ropinirole Preparation Products And Raw materials

Raw materials

Tetrazole Indole

Preparation Products

Less

Ropinirole Suppliers

Canada 2 China 116 Europe 2 Germany 1 India 10 The Netherlands 1 United Kingdom 3 United States 22 Global 157

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18207
Advantage: 66

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 4552
Advantage: 62

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2871
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

Shanghai T&W Pharmaceutical Co., Ltd.

Tel: +86 21 61551611
Fax: +86 21 50676805
Country: China
ProdList: 9891
Advantage: 58

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Wuhan DKY Technology Co.,Ltd.

Tel: 27-81302488 18007166089
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 2024
Advantage: 58

Shanghai HuanChuan Industry Co.,Ltd.

Tel: 021-61478794
Fax: 021-61478794
Email: sales@hcshhai.com
Country: China
ProdList: 9793
Advantage: 50

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9958
Advantage: 58

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Struchem Co., Ltd.

Tel: 0512-0512-63009836 15365350169
Fax: 0512-63006936
Email: helen@struchem.com
Country: China
ProdList: 3984
Advantage: 60

Pharmacodia (Beijing) Co.,Ltd

Tel: +86-400-851-9921
Fax: +86-10-82826195
Email: sales@pharmacodia.com
Country: China
ProdList: 2317
Advantage: 55

Henan CoreyChem Co., Ltd

Tel: 0371-86658258
Fax: 0371-60996044
Email: info@coreychem.com
Country: China
ProdList: 10453
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Shenzhen SUNGENING Bio-Medical Co., Ltd.

Tel: 0755-28967200 13631290199
Fax: 0755-28967200
Email: wxf@sungening.com
Country: China
ProdList: 9577
Advantage: 60

Shanghai Orgchem Co.,Ltd.

Tel: +86-21-5877 1921
Fax: +86-21-5877 1925
Email: info@chemofchina.com
Country: China
ProdList: 9653
Advantage: 55

Jiaxing Deyi Chemical Co., Ltd.

Tel: 0573-86-0573-85866609 13325730825
Fax: 0573-85866609
Email: 945717149@qq.com
Country: China
ProdList: 8025
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: +86-（0）57185586718 +86-13336195806
Fax: +86-571-85864795
Email: sales@capot.com
Country: China
ProdList: 29791
Advantage: 60

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

Shaanxi Pioneer Biotech Co., Ltd.

Tel: 029-029-86629612 18202932191
Email: sales3@pioneerbiotech.com
Country: China
ProdList: 336
Advantage: 55

Jinan Yaoyan Pharmaceutical Co., Ltd.

Tel
Fax: -
Email: jnyaoyan@163.com
Country: China
ProdList: 3069
Advantage: 58

Nanjing crow LuNing pharmaceutical technology co., LTD

Tel: 13382066392
Country: CHINA
ProdList: 4877
Advantage: 58

Pinghu city zhengyuan medical technology co. LTD

Tel: 18367600069
Fax: QQ3388371646
Email: pinghushizy@163.com
Country: China
ProdList: 7803
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4391
Advantage: 58

Hunan chemfish Scientific co.,ltd

Tel: 0731-85567275 15528049369
Email: sales@chemfish.com
Country: China
ProdList: 4959
Advantage: 58

Shaanxi Jiandu Pharmaceutical Chemical Co. Ltd.

Tel: 029-88380327 17691182729
Fax: 029-88380327
Email: 1018@dideu.com
Country: China
ProdList: 1993
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57412
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Shijiazhuang Gantuo Biotechnology Co., Ltd

Tel: +8613373514458
Email: gantuo02@cngantuo.com
Country: China
ProdList: 203
Advantage: 58

Xi'an MC Biotech, Co., Ltd.

Tel: 029-89275612 +8618991951683
Fax: 8618991951683
Email: mcbio_sales@163.com
Country: China
ProdList: 2251
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 22883
Advantage: 58

Hefei Hirisun Pharmatech Co., Ltd

Tel: +8615056975894
Fax: 86-0551-62678551
Email: shawn@hirisunpharm.com
Country: CHINA
ProdList: 9911
Advantage: 58

Baoji Guokang Healthchem co.,ltd

Tel: +8615604608665 15604608665
Email: dominicguo@gk-bio.com
Country: CHINA
ProdList: 9414
Advantage: 58

Baoji Guokang Bio-Technology Co., Ltd.

Tel: 0917-3909592 13892490616
Fax: 09173909592
Email: gksales1@gk-bio.com
Country: China
ProdList: 9314
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15354
Advantage: 58

Guangzhou Dreampharm Biotechnology Co., Ltd.

Tel: 020-36607679 17825480238
Fax: QQ 3008233717
Email: 3008233717@qq.com
Country: China
ProdList: 9919
Advantage: 12

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: 0731-85567275 18932438858
Fax: QQ:3554193828
Email: sales@chemfish.com
Country: China
ProdList: 8356
Advantage: 58

Jinan Ruisi Pharmaceutical Technology Co., LTD

Tel: 0531-69900633 18340090523
Email: changyuan20@163.com
Country: China
ProdList: 2585
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39894
Advantage: 58

Guangzhou Younan Technology Co., Ltd

Tel: 020-82000279 18988968278
Fax: QQ：3283937693
Email: sales@ubiochem.com
Country: China
ProdList: 4297
Advantage: 58

Absin Bioscience Inc.

Tel: 021-38015121 15000105423
Email: wulan@absin.cn
Country: China
ProdList: 24731
Advantage: 58

Xi'an Kono chem co., Ltd.

Tel: 029-84385017-8006 15891391030
Email: info@konochemical.com
Country: China
ProdList: 806
Advantage: 58

Zhongxin Chenshi (Wuhan) Technology Co., Ltd

Tel: 18942922096
Fax: QQ 2662561040
Email: 2662561040@qq.com
Country: China
ProdList: 1001
Advantage: 58

Less

View Lastest Price from Ropinirole manufacturers

Binzhou Lista Trading Limited

Product: Ropinirole 91374-21-9
Price: US $90.00-80.00/kg
Min. Order: 1kg
Purity: 99.99%
Supply Ability: 2000kg
Release date: 2024-08-12

Hebei Mingeng Biotechnology Co., Ltd

Product: Ropinirole 91374-21-9
Price: US $200.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg/Month
Release date: 2022-11-27

Shijiazhuang Gantuo Biotechnology Co., Ltd

Product: Ropinirole 91374-21-9
Price: US $100.00/mg
Min. Order: 25mg
Purity: 99%
Supply Ability: 1000g
Release date: 2023-03-10

91374-21-9, RopiniroleRelated Search:

Tetraethylammonium hydroxide cis-Octahydro-isoindole Nile Red 1-(2,6-Dichlorophenyl)indolin-2-one ROPINIROLE HYDROCHLORIDE,ROPINIROLE HCL Ropinirole Intermediate 3 Ropinirole Intermediate 6 4-(2-BroMoethyl)-1,3-dihydro-2H-indolin-2-one Ropinirole Intermediate 1 2-Butanone Ropinirole Intermediate 5 ROPINIROLE-D3, HYDROCHLORIDE 3-Oxo Ropinirole (Ropinirole Impurity C),Ropinirole Impurity C N-Despropyl Ropinirole-d3Discontinued see product # D297382,N-Despropyl Ropinirole-d3 N-PROPYL-D7-AMINE N-Despropyl RopiniroleDiscontinued see product # D297380,N-DESPROPYL ROPINIROLE DI-N-PROPYL-1,1,2,2,3,3,3-D7-AMINE (MONO-PROPYL-D7) Ropinirole

ROPINIROLE

4-(2-dipropylaminoethyl)-1,3-dihydroindol-2-one

ROPINIROLE: ROPINIROLE HYDROCHLORIDE

ROPINIROLE INTERMEIDATES:

ROPINIROLE 99%

4-[2-(Dipropylamino)ethyl]-1，3-dihydrcr2H-indol-2-one

SKF-101468

SKF-101468A：ReQuip

4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one

4-[2-(Dipropylamino)ethyl]indoline-2-one

2H-Indol-2-one, 4-(2-(dipropylamino)ethyl)-1,3-dihydro-

91374-20-8 (Hydrochloride)

Ropinirol [inn-spanish]

Ropinirolum

Ropinirolum [inn-latin]

Unii-030pyr8953

Ropinirole base

Ropinirole(Hydrochloride form)

(3S)-3-bromo-2-oxobutanoic acid

Ropinirole USP/EP/BP

Ropinirole Impurity 22

Ropinirole Impurity 23

Ropinirole Impurity 24

4-(2-(Dipropylamino)ethyl)indolin-2-one

Ropinirole (SKF-101468)

RSYYRopinirole

RSYYIbrutinib Impurity 141

91374-21-9

91374-58-8

C16H24N2O

API

ACTIVE PHARMACEUTICAL INGREDIENTS

Pharmaceutical material and intermeidates

Antiparkinsonian