ChemicalBook > CAS DataBase List > PVM/MA
PVM/MA
- Product Name
- PVM/MA
- CAS No.
- 1644545-52-7
- Chemical Name
- PVM/MA
- Synonyms
- E7386;AG881;AG081;HS-01;E-7386;PVM/MA;AG-881;s-22611;FF10101;CS-2621
- CBNumber
- CB91403717
- Molecular Formula
- C14H13ClF6N6
- Formula Weight
- 414.74
- MOL File
- 1644545-52-7.mol
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PVM/MA Property
- Boiling point:
- 467.5±55.0 °C(Predicted)
- Density
- 1.491±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
- form
- A crystalline solid
- pka
- 1.49±0.41(Predicted)
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
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N-Bromosuccinimide Price
Cayman Chemical
- Product number
- 28462
- Product name
- Vorasidenib
- Packaging
- 1mg
- Price
- $110
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28462
- Product name
- Vorasidenib
- Packaging
- 10mg
- Price
- $757
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 28462
- Product name
- Vorasidenib
- Packaging
- 5mg
- Price
- $433
- Updated
- 2024/03/01
ChemScene
- Product number
- CS-8033
- Product name
- Vorasidenib
- Purity
- 99.87%
- Packaging
- 5mg
- Price
- $150
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-8033
- Product name
- Vorasidenib
- Purity
- 99.87%
- Packaging
- 10mg
- Price
- $250
- Updated
- 2021/12/16
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PVM/MA Chemical Properties,Usage,Production
Uses
PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.
Synthesis
Maleic anhydride (MA) was added to a solvent mixture of cyclohexane and ethyl acetate in a polymerizer equipped with an agitator, a reflux condenser, and an inner temperature-controlling device. The polymerizer was purged of air and filled with nitrogen. The solution was heated to 70 °C, and then an initiator solution (lauroyl peroxide dissolved in ethyl acetate) and Methyl vinyl ether (MVE) were added to the polymerizer in a dropwise manner. A slurry was obtained, which was filtered and dried under a vacuum to obtain a white powdery copolymer.
PVM/MA Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from PVM/MA manufacturers
Wuhan Nutra Biotechnology Co.,Ltd
- Product
- Vorasidenib;AG-881 1644545-52-7
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 100kgs
- Release date
- 2021-05-24
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