ChemicalBook > CAS DataBase List > PVM/MA

PVM/MA

Product Name
PVM/MA
CAS No.
1644545-52-7
Chemical Name
PVM/MA
Synonyms
E7386;AG881;AG081;HS-01;E-7386;PVM/MA;AG-881;s-22611;FF10101;CS-2621
CBNumber
CB91403717
Molecular Formula
C14H13ClF6N6
Formula Weight
414.74
MOL File
1644545-52-7.mol
More
Less

PVM/MA Property

Boiling point:
467.5±55.0 °C(Predicted)
Density 
1.491±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.33 mg/ml
form 
A crystalline solid
pka
1.49±0.41(Predicted)
color 
Light yellow to light brown
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
28462
Product name
Vorasidenib
Packaging
1mg
Price
$110
Updated
2024/03/01
Cayman Chemical
Product number
28462
Product name
Vorasidenib
Packaging
10mg
Price
$757
Updated
2024/03/01
Cayman Chemical
Product number
28462
Product name
Vorasidenib
Packaging
5mg
Price
$433
Updated
2024/03/01
ChemScene
Product number
CS-8033
Product name
Vorasidenib
Purity
99.87%
Packaging
5mg
Price
$150
Updated
2021/12/16
ChemScene
Product number
CS-8033
Product name
Vorasidenib
Purity
99.87%
Packaging
10mg
Price
$250
Updated
2021/12/16
More
Less

PVM/MA Chemical Properties,Usage,Production

Uses

PF-06291874 is a novel and potent glucagon receptor antagonist for the potential treatment of diabetes mellitus. PF-06291874, has a lower molcular weight and lipophilicity than historical glucagon receptor antagonists, resulting in excellent selectivity in broad-panel screening, lower cytotoxicity, and excellent overall in vivo safety in early pre-clinical testing.

Synthesis

Maleic anhydride (MA) was added to a solvent mixture of cyclohexane and ethyl acetate in a polymerizer equipped with an agitator, a reflux condenser, and an inner temperature-controlling device. The polymerizer was purged of air and filled with nitrogen. The solution was heated to 70 °C, and then an initiator solution (lauroyl peroxide dissolved in ethyl acetate) and Methyl vinyl ether (MVE) were added to the polymerizer in a dropwise manner. A slurry was obtained, which was filtered and dried under a vacuum to obtain a white powdery copolymer.

PVM/MA Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

PVM/MA Suppliers

Pharma Affiliates
Tel
--
Fax
--
Email
@pharmaffiliates.com
Country
India
ProdList
6754
Advantage
58
Pharmaffiliates Analytics and Synthetics P. Ltd
Tel
--
Fax
--
Email
mktg@pharmaffiliates.com
Country
India
ProdList
6739
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from PVM/MA manufacturers

Wuhan Nutra Biotechnology Co.,Ltd
Product
Vorasidenib;AG-881 1644545-52-7
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
100kgs
Release date
2021-05-24

1644545-52-7, PVM/MARelated Search:


  • PF06291874
  • Vorasidenib
  • E7386
  • E-7386
  • s-22611
  • FM381 FM-381
  • 6-(6-chloropyridin-2-yl)-N2,N4-bis((R)-1,1,1-trifluoropropan-2-yl)-1,3,5-triazine-2,4-diamine
  • PVM/MA
  • S-N-NITROSO-2-METHYLPIPERIDINE
  • PCB138/160
  • FLEABUSTERSRXPOWDER
  • 15-HYDROPEROXYEICOSATETRAENOICACID
  • CALCIUM(C10-C16)ALKYLBENZENESULPHONATE
  • (5Z,8Z,11Z,14Z)-15-Hydroperoxy-5,8,11,14-icosatetraenoic acid
  • (5Z,8Z,11Z,14Z)-15-Hydroperoxyicosa-5,8,11,14-tetraenoic acid
  • 15-HPETE
  • AG881
  • AG-881
  • 4-(2-acetyl-5-chlorophenyl)-5-methoxypyridin-2(1H)-one
  • Amino Carboxyl Magnetic Beads
  • AG081
  • FF10101
  • FF-10101
  • benzyl ester of L-carnitine
  • CS-2621
  • AG 881; AG-881
  • 3-bromo-5-bromoacetyl salicylamide
  • (R)-1-(3-(3-amino-6-(2-fluoro-5-isopropoxyphenyl)pyrazine-2-carboxamido)pyridin-4-yl)piperidine-3-carboxylic acid?
  • N,N-dimethyl-N-(oxiran-2-ylmethyl)octadecan-1-aminium chloride
  • Vorasidenib (AG881)
  • Trichloroethyl 2-(Bromomethyl)-2-hydroxyhehahydrofuro(3,2-b)pyridine-4(2H)-carboxylate
  • 2-[3-(2H-indazol-3-ylmethyl)-2,4-dioxo-5-phenyl-1,5-benzodiazepin-1-yl]-N-(4-methoxyphenyl)-N-propan-2-ylacetamide
  • 2,2'-(propane-2,2- diylbis(sulfanediyl))bis(ethan-1-ol)
  • (E)-Ethyl Docos-2-Enoate
  • HS-01
  • 1,3,5-Triazine-2,4-diamine, 6-(6-chloro-2-pyridinyl)-N2,N4-bis[(1R)-2,2,2-trifluoro-1-methylethyl]-
  • 2-[1-(2-Hydroxy-ethylsulfanyl)-1-methyl-ethylsulfanyl]-ethanol
  • 4-N-(2,4-dimethoxyphenyl)-6-N-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-4,6-diamine, N4-(2,4-dimethoxyphenyl)-N6-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-4,6-diamine
  • IMB-XH1
  • 2-chloro-N1,N4-bis(4-cyanophenyl)terephthalamide
  • (+)-Quassin
  • high quality 3-aminophenylacetylene HCL
  • Sodium 2,3,3,3-Tetrafluoro-2-(1,1,2,2,2-Pentafluoroethoxy)propanoate
  • 2‐{2‐[2‐(2,2‐difluoroethoxy)ethoxy]ethoxy}‐1,1‐difluoroethane
  • 4-hydrazineylnicotinamide
  • inhibit,AG 881,Vorasidenib,AG881,Inhibitor,Isocitrate Dehydrogenase (IDH)
  • SRD5A1-IN-1
  • AKR1C3-IN-9
  • ARUK2001607
  • TLC Plates,Silca Gel 60 F254 Aluminium Plating
  • 2-(1-ethoxyvinyl)-4,4,5,5-tetraethyl-1,3,2-dioxaborolane
  • (S)-1-amino-1-(5-bromo-2-fluorophenyl)ethan-1-ol
  • N-Difluoromethyltriazolyl-4-carboxamide
  • N-Trifluoromethyltriazolyl-4-carboxamide
  • 4-Cyano-1-(perfluoroethoxy)pyridin-1-ium bis((trifluoromethyl)sulfonyl)amide
  • Sodium 2-azido-2,2-difluoroacetate
  • (1-(2,2,3,3-Tetrafluoropropyl)-1H-1,2,3-triazol-4-yl)methanaminium chloride
  • 1-Difluoroethyltriazolyl-4-methylamine hydrochloride