ChemicalBook > CAS DataBase List > Teflubenzuron

Teflubenzuron

Chemical properties Uses Production Method Hazards & Safety Information

Product Name: Teflubenzuron
CAS No.: 83121-18-0
Chemical Name: Teflubenzuron
Synonyms: dart;MK139;HOE522;NOMOLT;NEMOLT;cme134;diaract;cme13406;TEFLURON;Terfluron
CBNumber: CB9155082
Molecular Formula: C14H6Cl2F4N2O2
Formula Weight: 381.11
MOL File: 83121-18-0.mol

Less

Teflubenzuron Property

Melting point:: 221-224°
Density: 1.646±0.06 g/cm3(Predicted)
vapor pressure: 8 x 10 -7 mPa (20 °C)
storage temp.: 0-6°C
solubility: DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
Water Solubility: 0.019 mg l^-1 (23 °C)
pka: 8.16±0.46(Predicted)
color: White to Off-White
Merck: 13,9190
BRN: 8229925
LogP: 4.98 at 20℃ and pH4.7
CAS DataBase Reference: 83121-18-0(CAS DataBase Reference)
EPA Substance Registry System: Teflubenzuron (83121-18-0)

Less

Safety

RIDADR: 3077
WGK Germany: 2
RTECS: CV3459590
HazardClass: 9
PackingGroup: III
Toxicity: LD50 orally in rats: >5000 mg/kg (Becher)

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P314Get medical advice/attention if you feel unwell.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 45756
Product name: Teflubenzuron
Purity: PESTANAL?, analytical standard
Packaging: 250mg
Price: $74.5
Updated: 2025/07/31

AK Scientific

Product number: P035
Product name: Teflubenzuron
Packaging: 250mg
Price: $174
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0352707
Product name: TELFUBENZURON
Purity: 95.00%
Packaging: 5MG
Price: $495.02
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 42291
Product name: Teflubenzuron
Packaging: 25g
Price: $1475
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PST0000194
Product name: TEFLUBENZURON
Purity: 95.00%
Packaging: 25G
Price: $2061.68
Updated: 2021/12/16

Less

Teflubenzuron Chemical Properties,Usage,Production

Chemical properties

Pure Teflubenzuron is white crystal. m.p.223～225℃ (The original compound 222.5℃)，saturated vapor pressure0.8×10-9Pa(20℃), relative density 1.68(20℃). Its solubility at 20～23℃ are 66g/L in dimethyl sulfoxide, 20g/L in cyclohexanone, 10g/L in acetone, 1.4g/L in ethanol, 850mg/L in methylbenzene， 50mg/L in hexane, 0.02mg/L in water. Stable at room temperature. Its hydrolysis half-life period are 5d（pH=7）and 4h (pH=9） at 50℃ and 2～6 weeks in soil.

Uses

Teflubenzuron’s a fluorobenzoylurea insect growth regulator and a chitinase inhibitor. It achieves the insecticidal purpose through the inhibition of normal molting and development of larvae. It has a particularly high activity on lepidoptera pests, also achieves a good effect when it comes to the larvae of whitefly families, diptera, hymenoptera, coleoptera pests, but it’s invalid for many parasitic insects, predatory insects and spiders. It is mainly used on vegetables, fruit trees, cotton and teabush. E.g. 2000~4000 times diluent of EC can be applied by spraying to larvae of cabbage caterpillar and plutella xylostella in the egg incubation period to 1 to 2 instar.1500～3000 times diluent of EC can be applied by spraying to larvae of plutella xylostella, asparagus caterpillar, prodenia litura in the egg incubation period to 1 to 2 instar, which are resistant to organic phosphorus and pyrethroids. 1500～2000 times diluent of EC can be applied by spraying to cotton bollworm and pink worm in the egg incubation period of the second and third generations, and the elimination rate is about 85% after 10 days.

Production Method

Method 1
The addition reaction of 2,6-Difluorobenzamide and 2,4-difluoro-3,5-dichlorophenyl isocyanate
Method 2
preparation of 2,4-Difluoro-3,5-dichlorophenylamine
2,3,4,5-tetrachloronitrobenzene and Potassium fluoride react in DMF solvent at 140℃ for 15h to obtain 2,4-Difluoro-3,5-dichloronitrobenzene，which is then reduced to 2,4-Difluoro-3,5-dichlorophenylamine
Preparation of Teflubenzuron
As for the preparation of 2,6-difluorobenzoyl isocyanate, see details in the preparation of Teflubenzuron.
2,6-difluorobenzoyl isocyanate and 2,4-Difluoro-3,5-dichlorophenylamine react at room temperature for 15h to obtain Teflubenzuron
As for the nitrification, chlorination, reduction, fluorization and condensation of 1,2,4-Trichlorobenzene to prepare Teflubenzuron, see details in bibliography.

Hazards & Safety Information

Category: Pesticide
Toxicity Grade: low toxicity
Acute Toxicity: LD50: 5000 mg/ kg(Rats oral)
Flammability: Flammable with toxic gases of nitrogen oxides, fluorides and chlorides
Storage: in dry ventilated storeroom at low temperature, away from food materials
Extinguishant: dry powder extinguisher, foam extinguisher, sand.

Uses

Teflubenzuron is used for the control of Lepidoptera, Coleoptera, Diptera, Aleyrodidae, Hymenoptera, Psyllidae and Hemiptera larvae on vines, pome fruit, citrus, vegetables, soyabeans, tobacco and cotton. It also controls fly and mosquito larvae and immature stages of locusts.

Uses

Teflubenzuron is an benzoylphenylurea chitin synthesis inhibitor used to control a wide range of insect pests and mites in fruit, vegetable, cereal and seed crops.

Uses

uSE: Insecticide.

Definition

ChEBI: Teflubenzuron is a N-acylurea that is N-carbamoyl-2,6-difluorobenzamide substituted by a 3,5-dichloro-2,4-difluorophenyl group at the terminal nitrogen atom. It has a role as a xenobiotic, an environmental contaminant and an insecticide. It is a dichlorobenzene, a N-acylurea and a difluorobenzene. It is functionally related to a N-benzoylurea.

Metabolic pathway

There is limited published information on the metabolism of teflubenzuron but an IPCS review is in preparation. Metabolic processes reported are cleavage of the urea bond and hydroxylation of both phenyl rings, including replacement of a fluorine in the 3,5-dichloro-2,4-difluorophenyl ring (see Scheme 1).

Degradation

Teflubenzuron is more readily hydrolysed at alkaline pH than in acid media. The DT₅₀ at 50 °C was 5 days at pH 7 and 4 hours at pH 9 (PM).

Toxicity evaluation

Acute oral LD₅₀ for rats: >5,000 mg/kg

Teflubenzuron Preparation Products And Raw materials

Raw materials

3,5-dichlorophenyl isocyanate 2,6-Difluorobenzamide 2,6-Difluorobenzoyl isocyanate 3,5-Dichloronitrobenzene Chlorfluazuron 2,3,4,5-Tetrachloronitrobenzene 3,5-Dichloroaniline

Preparation Products

Less

Teflubenzuron Suppliers

Canada 1 China 159 France 1 Germany 2 India 1 Japan 2 Switzerland 1 United Kingdom 5 United States 17 Global 189

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Wuhan Sinocon New chemical Materials Co.,ltd.

Tel: 027-83229541 13971313286
Fax: 027-83096702
Email: whsinocon@aliyun.com
Country: China
ProdList: 127
Advantage: 62

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3239
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

TianJin Alta Scientific Co., Ltd.

Tel: 022-65378550-8551
Fax: +86-022-2532-9655
Email: contact@altascientific.com
Country: China
ProdList: 2773
Advantage: 58

ChemStrong Scientific Co.,Ltd

Tel: 0755-0755-66853366 13670046396
Fax: 0755-28363542
Email: sales@chem-strong.com
Country: China
ProdList: 18333
Advantage: 56

Shanghai Kewel Chemical Co., Ltd.

Tel: 021-64609169 18901607656
Fax: 021-64609160
Email: greensnown@163.com
Country: China
ProdList: 9906
Advantage: 50

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Chizhou Kailong Import and Export Trade Co., Ltd.

Tel
Fax: -
Email: xg01_gj@163.com
Country: China
ProdList: 9484
Advantage: 50

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4511
Advantage: 55

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 6687
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Raw material medicin reagent co.,Ltd

Tel
Email: sales@njromanme.com
Country: China
ProdList: 4529
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Wuhai Shuou Technology Co., Ltd.

Tel: 17792809151
Fax: 18872220797
Email: 2355916837@ycphar.com
Country: China
ProdList: 6133
Advantage: 55

Hubei Yangxin Medical Technology Co., Ltd.

Tel: 15374522761
Fax: QQ:2853117752
Email: 3003392093@yongstandards.com
Country: China
ProdList: 10001
Advantage: 55

Taian Jiaye Biotechnology Co.Ltd

Tel: 13127280945
Email: 285424065@qq.com
Country: China
ProdList: 9976
Advantage: 55

Shanghai Orgchem Co.,Ltd.

Tel: +86-21-5877 1921
Fax: +86-21-5877 1925
Email: info@chemofchina.com
Country: China
ProdList: 9653
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Wuhan Netcom Electronic Commerce Limited

Tel: 18064670521
Fax: 0757-88210752
Email: 2355935187@ycphar.com
Country: China
ProdList: 4879
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9750
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Ningbo Zhenlei Chemical Co.,ltd.

Tel: 0576-88808091 17681642513
Fax: +0576-88203603
Email: jardon.liang@zhenleichem.com
Country: China
ProdList: 122
Advantage: 58

Foshan DaoQi Biological Co., Ltd.

Tel: 18062666947
Fax: 18062666959
Email: 2355880548@qq.com
Country: China
ProdList: 4228
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10267
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Beijing altar ink quality inspection technology co., LTD

Tel: 010-52889049
Email: 2250970673@qq.com
Country: CHINA
ProdList: 1132
Advantage: 58

Guangdong wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2815688 13927872512
Fax: 0751-8963795
Email: 3007421951@qq.com
Country: China
ProdList: 9939
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8615838112936
Email: alfa10@alfachem.cn
Country: China
ProdList: 12921
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418684 +8618949823763
Fax: 0086-551-65418684
Email: sales@tnjchem.com
Country: China
ProdList: 25356
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20342
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Longyan Tianhua Biological Technology Co., Ltd

Tel: 0086 18039857276 18039857276
Country: CHINA
ProdList: 2783
Advantage: 58

Hubei Jusheng Technology Co.,Ltd.

Tel: 18871490254
Fax: 027-59599243
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 28172
Advantage: 58

Chengdu Peter-like Biotechnology Co., Ltd.

Tel: 18108052721
Email: 2850505130@qq.com
Country: China
ProdList: 5167
Advantage: 58

Hubei xin bonus chemical co. LTD

Tel: 86-13657291602
Fax: 027-59338440
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 22963
Advantage: 58

Shandong chuangyingchemical Co., Ltd.

Tel: 18853181302
Email: sale@chuangyingchem.com
Country: CHINA
ProdList: 5906
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39927
Advantage: 58

Wuhan Xinru Chemical Co., Ltd.

Tel: 15927387915 15337108568
Email: 2769903731@qq.com
Country: China
ProdList: 3336
Advantage: 58

Shanghai Jiegu Biotechnology Co., Ltd.

Tel: 021-51698675
Email: sales@jiejiegroup.com
Country: China
ProdList: 8020
Advantage: 58

wuhan dingxingtong Chemical Technology Co., Ltd Co., Ltd

Tel: 027-59207796 13429867250
Fax: 027-59207796
Email: w13429867250@163.com
Country: China
ProdList: 1995
Advantage: 58

Shenyang Maud Pharmaceutical Technology Co., Ltd.

Tel: 024-23982345
Email: 1020788318@qq.com
Country: China
ProdList: 2251
Advantage: 58

Wuhan Rongcan Biotechnology Co., Ltd

Tel: 18327024450
Fax: 183-27024450
Email: 2130026275@qq.com
Country: China
ProdList: 4553
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

ShangHai Anpel Co, Ltd.

Tel: 18501792038 18502138905
Email: shanpel@anpel.com.cn
Country: China
ProdList: 9611
Advantage: 58

Less

View Lastest Price from Teflubenzuron manufacturers

Henan Fengda Chemical Co., Ltd

Product: teflubenzuron 83121-18-0
Price: US $9.00-0.90/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-23

Longyan Tianhua Biological Technology Co., Ltd

Product: Teflubenzuron 83121-18-0
Price: US $60.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 20 Tons
Release date: 2020-10-28

Career Henan Chemical Co

Product: Teflubenzuron 83121-18-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-14

83121-18-0, TeflubenzuronRelated Search:

Dichloromethylphenylsilane 4-Fluorobenzaldehyde 3-Fluoroanisole 1,3-Dichloro-1,3,5-triazinetrione,sodium salt Glycine PYRAZOPHOS Urea formaldehyde Florfenicol ALTRENOGEST Dichlorodiphenylsilane Transfluthrin 1-Chloro-4-fluorobenzene 4-FLUOROPHENYLUREA 2'-Fluoroacetanilide 1,3-DICHLORO-2,4-DIFLUOROBENZENE 1-CHLORO-2,4-DIFLUOROBENZENE 1-(3,5-dichlorophenyl)-3-methylurea (2,6-Difluoro-benzyl)-urea

n-(((3,5-dichloro-2,4-difluorophenyl)amino)carbonyl)-2,6-difluoro-benzamid

n-(((3,5-dichloro-2,4-diflurophenyl)amino)carbonyl)-2,6-difluorobenzamide

Teubenzuron Solution, 1000ppm

cme13406

dart

diaract

Nomolt(TM)

N-[(3,5-dichloro-2,4-difluoroanilino)-oxomethyl]-2,6-difluorobenzamide

teflubenzuron (bsi,iso)

TERFLUORON

3,5-dichloro-2,4-difluorophenyl) 3-(2,6-difluorobenzoyl)

Terfluron

TEFLUBENZURON PESTANAL, 250

TELFUBENZURON

CME-134-01

Nsc367306

Teflubenzuron 250mg [83121-18-0]

Teubenzuron

HOE522

1-(3,5-dichloro-2,4-difluorophenyl)-3-(2,6-difluorobenzoyl)urea

TEFLUBENZURON

TEFLURON

n-[[(3,5-dichloro-2,4-difluorophenyl)amino]carbonyl]-2,6-difluorobenzamide

MK139

NOMOLT

NEMOLT

cme134

Teflubenzuron@1000 μg/mL in Acetonitrile

Teflubenzuron @100 μg/mL in MeOH

Teflubenzuron Reference Material

Teflubenzuron-15N-d3

Novaluron Impurity 2

Fuchong Long

Teflubenzuron in Acetone

Teflubenzuron 10 μg/ml Cyclohexane

Teflubenzuron 100 μg/ml Acetonitrile

Teflubenzuron 100 μg/ml Methanol

C17210000 Teflubenzuron

Teflubenzuron in Methanol

Canada Pesticide Mixture 3 100ug/mL in Toluene

83121-18-0

C14H6CL2F4N2O2

Alpha sort

Growth regulatorsPesticides&Metabolites

Insecticides

Pesticides

Q-ZAlphabetic

TA - TE