ChemicalBook > CAS DataBase List > DIMINAZENE ACETURATE

DIMINAZENE ACETURATE

Product Name
DIMINAZENE ACETURATE
CAS No.
908-54-3
Chemical Name
DIMINAZENE ACETURATE
Synonyms
CL218;azidin;ganaseg;ganasag;azidine;beronal;BERENIL;DIMINAZINE;amide](2:1);DiaMinazene
CBNumber
CB9161027
Molecular Formula
C22H29N9O6
Formula Weight
515.52
MOL File
908-54-3.mol
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DIMINAZENE ACETURATE Property

Melting point:
202 °C
storage temp. 
Inert atmosphere,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
powder
color 
Orange to Dark Orange
Water Solubility 
Soluble to 100 mM in water
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
908-54-3(CAS DataBase Reference)
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Safety

WGK Germany 
3
RTECS 
MB7605000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D7770
Product name
Diminazene aceturate
Purity
analytical standard
Packaging
1g
Price
$74.1
Updated
2025/07/31
Cayman Chemical
Product number
18678
Product name
Diminazene (aceturate)
Purity
≥98%
Packaging
1g
Price
$48
Updated
2024/03/01
Cayman Chemical
Product number
18678
Product name
Diminazene (aceturate)
Purity
≥98%
Packaging
5g
Price
$152
Updated
2024/03/01
Cayman Chemical
Product number
18678
Product name
Diminazene (aceturate)
Purity
≥98%
Packaging
25g
Price
$693
Updated
2024/03/01
Tocris
Product number
6705
Product name
Diminazene aceturate
Purity
≥98%(HPLC)
Packaging
100
Price
$79
Updated
2021/12/16
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DIMINAZENE ACETURATE Chemical Properties,Usage,Production

Description

Diminazene is a diamidine that is cytotoxic to protozoa, including Trypanosoma, Babesia, and Cytauxzoon. Diamidines, including diminazene, affect a variety of enzymes and modulate interactions between nucleic acids and proteins. Diminazene inhibits diamine oxidase with a Ki value of 13 nM. In Trypanosoma, transport proteins are important in the effectiveness of diminazene. In rats and in vitro, diminazene enhances the enzymatic activity of angiotensin-converting enzyme 2.

Chemical Properties

solid

Uses

antiprotozoal as aceturate

Uses

An anti-protozoal and anti-trypanosomal compound

Uses

Diminazene aceturate is an anti-protozoal drug. Diminazene Diaceturate is used as an anti-trypanosomal agent.

Definition

ChEBI: An N-acetylglycinate salt resulting from the reaction of diminazene with 2 mol eq. of N-acetylglycine.

Veterinary Drugs and Treatments

Diminazene is used to treat trypanosomiasis in dogs and livestock (sheep, goats, cattle), Babesia infections in dogs and horses, and cytauxzoonosis in cats. The drug is not commercially available in the USA, but is available and used in many countries.

storage

Store at RT

References

[1] J MOSQUEDA. Current advances in detection and treatment of babesiosis.[J]. Current medicinal chemistry, 2012, 19 10: 1504-1518. DOI: 10.2174/092986712799828355
[2] GEORGE LAYLSON DA SILVA OLIVEIRA  Rivelilson M de F. Diminazene aceturate—An antiparasitic drug of antiquity: Advances in pharmacology & therapeutics[J]. Pharmacological research, 2015, 102: Pages 138-157. DOI: 10.1016/j.phrs.2015.10.005
[3] TIEN L. HUANG  Jean J V E  Annie Mayence. Some non-conventional biomolecular targets for diamidines. A short survey[J]. Bioorganic & Medicinal Chemistry, 2014, 22 7: Pages 1983-1992. DOI: 10.1016/j.bmc.2014.02.049
[4] JANE C MUNDAY H P de K Luca Settimo. Transport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma brucei.[J]. Frontiers in Pharmacology, 2015, 6: 32. DOI: 10.3389/fphar.2015.00032
[5] VINAYAK SHENOY. Diminazene attenuates pulmonary hypertension and improves angiogenic progenitor cell functions in experimental models.[J]. American journal of respiratory and critical care medicine, 2013, 187 6: 648-657. DOI: 10.1164/rccm.201205-0880oc

DIMINAZENE ACETURATE Preparation Products And Raw materials

Raw materials

4-Nitrobenzonitrile N-Acetylglycine 4-Nitrobenzoic acid triazene Sodium Methoxide p-Toluenesulfonamide Potassium iodide statch paper Iron

Preparation Products

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View Lastest Price from DIMINAZENE ACETURATE manufacturers

Hefei Lbao Physical & Chemical Science Co.,Ltd
Product
DIMINAZENE ACETURATE 908-54-3
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
Customise
Release date
2025-10-28
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Diminazene Diaceturate 908-54-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99.42%
Supply Ability
20TM
Release date
2024-05-18
Hebei Fengqiang Trading Co., LTD
Product
DIMINAZENE ACETURATE 908-54-3
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-08-11

908-54-3, DIMINAZENE ACETURATERelated Search:

Sulfanilic acid N-Acetylglycine Uric acid Diazoaminobenzene Diminazene A-AMINO-A-IMINOETHANE ACETATE 1-METHYL-3-P-TOLYLTRIAZENE 1,3-DIMETHYLTRIAZENE DIMINAZENE ACETURATE 4-Aminobenzamidine dihydrochloride 3-Methyl-1-phenyltriazene

  • CL218
  • Glycine, N-acetyl-, compd. with 4,4'-(1-triazene-1,3-diyl)bis[benzenecarboximidamide] (2:1)
  • 4,4’-(diamino)dibenzamidediaceturate
  • 4,4’-(Diazoamino)dibenzamidinediaceturate
  • ganasag
  • ganaseg
  • glycine,n-acetyl-,compd.with4,4’-(1-triazene-1,3-diyl)bis(benzenecarboxim
  • glycine,n-acetyl-,compd.with4,4’-(1-triazene-1,3-diyl)bis[benzenecarboximid
  • glycine,n-acetyl-,compd.with4,4’-(diazoamino)dibenzamidine(2:1)
  • idamide)(2:1)
  • N-Acetylglycinecompoundwith4,4’-(dia-zoamino)dibenzamidine
  • 4,4'-(1-Triazene-1,3-diyl)bis[benzenecarboximidamide] bis(N-acetylglycinate)
  • N-acetylglycine, compound with 4,4'-(1-triazene-1,3-diyl)bis[benzenecarboxamidine] (2:1)
  • p,p'-Diguanyldiazoaminobenzene diaceturate
  • DIMINAZINE
  • amide](2:1)
  • azidin
  • azidine
  • beronal
  • di-(4-amidinophenyl)-triazen-(n-1,3)-diaceturat
  • di-(4-amidinophenyl)-triazine-(n-1,3)-diaceturate
  • diaminazeneaceturate
  • DIMINAZENE ACETURATE
  • DIMINAZENE DIACETURATE
  • DIMINAZENE DIACTETURATE
  • DIMINAZINE ACETURATE
  • BERENIL
  • N-Acetylglycine 4,4'-(1-triazene-1,3-diyl)bis[benzenecarboxamidine] (2:1)
  • 1,3-Bis[4-guanylphenyl]triazene diaceturate
  • 4,4'-DiaMidinodiazoaMinobenzene Diaceturate
  • DiaMinazene
  • Glycine, N-acetyl-, compd. with4,4'-(1-triazene-1,3-diyl)bis[benzenecarboximidamide] (2:1)OTHER CA INDEX NAMES:Benzenecarboximidamide, 4,4'-(1-triazene-1,3-diyl)bis-, compd. withN-acetylglycine (1:2)
  • iminazenediaceturate
  • DIMINAZENE ACETURATE USP/EP/BP
  • Diminazene DiaceturateQ: What is Diminazene Diaceturate Q: What is the CAS Number of Diminazene Diaceturate Q: What is the storage condition of Diminazene Diaceturate
  • 3-ethyl-2-[2-[(3-ethyl-1,3-benzothiazol-3-ium-2-yl)methylidene]butylidene]-1,3-benzothiazole,iodide
  • 4,4'-(Triaz-1-ene-1,3-diyl)dibenzimidamide bis(2-acetamidoacetate)
  • Diminazene Oral Grade
  • Diminazene Aceturate, 10 mM in DMSO
  • Diminazene 1000 μg/mL in Acetonitrile:Water
  • 908-54-3
  • 563-71-0
  • C22H29N9O6
  • C14H15N72C4H7NO3
  • 2C4H7NO3C14H15N7
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