Fmoc-L-glutamic acid 5-tert-butyl ester

Product Name: Fmoc-L-glutamic acid 5-tert-butyl ester
CAS No.: 71989-18-9
Chemical Name: Fmoc-L-glutamic acid 5-tert-butyl ester
Synonyms: FMOC-GLU(OTBU)-OH;(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-5-(tert-butoxy)-5-oxopentanoic acid;FMOC-GLU(TBU)-OH;FMOC-L-GLU(OTBU)-OH;FMOC-L-GLU(TBU)-OH;Fomc-Glu(OtBu)-OH;5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate Hydrate;Fomc-Glu(O;u(OtBu)-OH;cas:71989-18-9
CBNumber: CB9161890
Molecular Formula: C24H27NO6
Formula Weight: 425.47
MOL File: 71989-18-9.mol

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Fmoc-L-glutamic acid 5-tert-butyl ester Property

Melting point:: 83-90 °C
alpha: -4.5 º (c=1, 80% acetic acid)
Boiling point:: 633.5±55.0 °C(Predicted)
Density: 1.232±0.06 g/cm3(Predicted)
refractive index: -4 ° (C=1, 80% AcOH)
storage temp.: Store below +30°C.
solubility: soluble in Methanol
form: powder to crystal
pka: 3.70±0.10(Predicted)
color: White to Almost white
optical activity: [α]20/D 5.0±2.0°, c = 1% in acetic acid: water (4:1)
BRN: 3636375
InChIKey: OTKXCALUHMPIGM-FQEVSTJZSA-N
SMILES: C(O)(=O)[C@H](CCC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference: 71989-18-9(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-27-36/37/39-24/25
WGK Germany: 3
HS Code: 2924 29 70

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.52009
Product name: Fmoc-Glu(OtBu)-OH
Purity: Novabiochem?
Packaging: 25g
Price: $74.8
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52009
Product name: Fmoc-Glu(OtBu)-OH
Purity: Novabiochem?
Packaging: 100g
Price: $225
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52009
Product name: Fmoc-Glu(OtBu)-OH
Purity: Novabiochem?
Packaging: 250g
Price: $480
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52009
Product name: Fmoc-Glu(OtBu)-OH
Purity: Novabiochem®
Packaging: 500 g
Price: $898
Updated: 2025/07/31

Sigma-Aldrich

Product number: 8.52009
Product name: Fmoc-Glu(OtBu)-OH
Purity: Novabiochem®
Packaging: 500 g
Price: $898
Updated: 2025/07/31

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Fmoc-L-glutamic acid 5-tert-butyl ester Chemical Properties,Usage,Production

Description

Fmoc-L-glutamic acid 5-tert-butyl ester is a Fmoc derivative with an N-substituted tert-butyl ester molecule. It is white or gray-white solid crystals at room temperature and pressure, poor solubility in water and insoluble in petroleum ether, but soluble in ethyl acetate, acetic acid and N,N-dimethylformamide.

Chemical Properties

White powder

Uses

Fmoc-Glu(OtBu)-OH (Fmoc-L-glutamic acid 5-tert-butyl ester) can be employed as a:

Ligand in the synthesis of cis-substituted cyclopropane carboxylic acids via C-H activation of cyclopropane carboxamides using Pd catalyst.
Linker in the preparation of multi-small molecule-conjugated PTX (paclitaxel) derivatives.

It can be also used as a building block in the preparation of stapled α-helical peptides , and peptide C-terminal thioesters .

General Description

Fmoc-L-glutamic acid 5-tert-butyl ester is a protected building block used for the introduction of glutamic acid into peptides.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Fmoc-L-glutamic acid 5-tert-butyl ester Preparation Products And Raw materials

Raw materials

Fluorene L-Glutamic acid 5-tert-butyl ester

Preparation Products

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Fmoc-L-glutamic acid 5-tert-butyl ester Suppliers

Americas 1 Canada 2 China 416 Europe 6 Germany 8 India 14 Israel 1 Japan 7 Poland 1 Switzerland 2 United Kingdom 14 United States 66 Global 538

Tiantai Yisheng Biochemical Technology Co., Ltd

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GL Biochem (Shanghai) Ltd

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Shanghai Jizhi Biochemical Technology Co. Ltd.

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INTATRADE GmbH

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Alfa Aesar

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View Lastest Price from Fmoc-L-glutamic acid 5-tert-butyl ester manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Fmoc-Glu(OtBu)-OH 71989-18-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%min
Supply Ability: 1000kg
Release date: 2025-10-29

Shanghai Joiny Pharmaceutical Co.,LTD

Product: Fmoc-Glu(OtBu)-OH 71989-18-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2025-10-24

Hebei Chuanghai Biotechnology Co., Ltd

Product: Fmoc-L-glutamic acid 5-tert-butyl ester 71989-18-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2024-12-03

71989-18-9, Fmoc-L-glutamic acid 5-tert-butyl esterRelated Search:

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FMOC-L-GLU(OTBU)-OH(71989-18-9)

FMOC-L-GLUTAMIC ACID 5-TERT-BUTYL ESTER

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Fmoc-Glu(Otbu)-OH(CAS:71989-18-9)

Fmoc-Glu(OtBu)-OH Hydrate