ChemicalBook > CAS DataBase List > Fmoc-L-glutamic acid 5-tert-butyl ester

Fmoc-L-glutamic acid 5-tert-butyl ester

Product Name
Fmoc-L-glutamic acid 5-tert-butyl ester
CAS No.
71989-18-9
Chemical Name
Fmoc-L-glutamic acid 5-tert-butyl ester
Synonyms
FMOC-GLU(OTBU)-OH;(S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-5-(tert-butoxy)-5-oxopentanoic acid;FMOC-GLU(TBU)-OH;FMOC-L-GLU(OTBU)-OH;FMOC-L-GLU(TBU)-OH;Fomc-Glu(OtBu)-OH;5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate Hydrate;Fomc-Glu(O;u(OtBu)-OH;cas:71989-18-9
CBNumber
CB9161890
Molecular Formula
C24H27NO6
Formula Weight
425.47
MOL File
71989-18-9.mol
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Fmoc-L-glutamic acid 5-tert-butyl ester Property

Melting point:
83-90 °C
alpha 
-4.5 º (c=1, 80% acetic acid)
Boiling point:
633.5±55.0 °C(Predicted)
Density 
1.232±0.06 g/cm3(Predicted)
refractive index 
-4 ° (C=1, 80% AcOH)
storage temp. 
Store below +30°C.
solubility 
soluble in Methanol
form 
powder to crystal
pka
3.70±0.10(Predicted)
color 
White to Almost white
optical activity
[α]20/D 5.0±2.0°, c = 1% in acetic acid: water (4:1)
BRN 
3636375
InChIKey
OTKXCALUHMPIGM-FQEVSTJZSA-N
SMILES
C(O)(=O)[C@H](CCC(OC(C)(C)C)=O)NC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O
CAS DataBase Reference
71989-18-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-27-36/37/39-24/25
WGK Germany 
3
HS Code 
2924 29 70
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H311Toxic in contact with skin

H331Toxic if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P310Immediately call a POISON CENTER or doctor/physician.

P330Rinse mouth.

P361Remove/Take off immediately all contaminated clothing.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.52009
Product name
Fmoc-Glu(OtBu)-OH
Purity
Novabiochem?
Packaging
25g
Price
$72.8
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52009
Product name
Fmoc-Glu(OtBu)-OH
Purity
Novabiochem?
Packaging
100g
Price
$219
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52009
Product name
Fmoc-Glu(OtBu)-OH
Purity
Novabiochem?
Packaging
250g
Price
$467
Updated
2024/03/01
Sigma-Aldrich
Product number
8.52009
Product name
Fmoc-Glu(OtBu)-OH
Purity
Novabiochem?
Packaging
1kg
Price
$1620
Updated
2024/03/01
Sigma-Aldrich
Product number
47625
Product name
Fmoc-Glu(OtBu)-OH
Purity
≥98.0% (HPLC)
Packaging
10g
Price
$197
Updated
2024/03/01
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Fmoc-L-glutamic acid 5-tert-butyl ester Chemical Properties,Usage,Production

Description

Fmoc-L-glutamic acid 5-tert-butyl ester is a Fmoc derivative with an N-substituted tert-butyl ester molecule. It is white or gray-white solid crystals at room temperature and pressure, poor solubility in water and insoluble in petroleum ether, but soluble in ethyl acetate, acetic acid and N,N-dimethylformamide.

Chemical Properties

White powder

Uses

Fmoc-Glu(OtBu)-OH (Fmoc-L-glutamic acid 5-tert-butyl ester) can be employed as a:

  • Ligand in the synthesis of cis-substituted cyclopropane carboxylic acids via C-H activation of cyclopropane carboxamides using Pd catalyst.
  • Linker in the preparation of multi-small molecule-conjugated PTX (paclitaxel) derivatives.

It can be also used as a building block in the preparation of stapled α-helical peptides , and peptide C-terminal thioesters .

General Description

The product number for this product was previously 04-12-1020.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

Fmoc-L-glutamic acid 5-tert-butyl ester Preparation Products And Raw materials

Raw materials

Fluorene L-Glutamic acid 5-tert-butyl ester

Preparation Products

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View Lastest Price from Fmoc-L-glutamic acid 5-tert-butyl ester manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Fmoc-L-Glu(OtBu)-OH 71989-18-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98+
Supply Ability
1T
Release date
2023-11-27
Hebei Mujin Biotechnology Co.,Ltd
Product
Fmoc-L-glutamic acid 5-tert-butyl ester 71989-18-9
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-25
Hebei Zhuanglai Chemical Trading Co Ltd
Product
Fmoc-L-glutamic acid 5-tert-butyl ester 71989-18-9
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-11-25

71989-18-9, Fmoc-L-glutamic acid 5-tert-butyl esterRelated Search:

butyl rubber Cyhalofop-butyl tert-Butanol PYRAZOPHOS tert-Butyllithium CARBONYL SULFIDE 2-Butoxyethanol Butyl acetate Methyl 4-tert-butylbenzoate 9-Fluorenylmethyl chloroformate L-Glutamic acid 1,1'-Carbonyldiimidazole tert-Butyl hydroperoxide Fmoc-Aib-OH 4-tert-Butylcatechol Fmoc-L-glutamic acid Butyl acrylate Buprofezin

  • N-ALPHA-FMOC-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
  • N-ALPHA-FMOC-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER
  • N-9-FLUORENYLMETHYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
  • N-9-FLUORENYLMETHYLOXYCARBONYL-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMIC-ACID-GAMMA-T-BUTYL ESTER
  • N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-GAMMA-T-BUTYL-L-GLUTAMIC ACID
  • N-FMOC-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
  • N-FMOC-O-T-BUTYL-L-GLU
  • FMOC-GLU(OBUT)-OH
  • FMOC-GLU(OTBU)-OH
  • FMOC-L-GLU(OTBU)-OH
  • (9-fluorenylmethoxycarbonyl)-L-glutamic acid 5-tert-butyl
  • N-FMOC-L-glitamic acid 5-t-butyl ester
  • 4-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
  • L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
  • Nα-Fmoc-L-glutamic-acid 5-tert-butyl ester ,98%
  • (S)-5-Oxo-5-tert-butoxy-2-[(9H-fluorene-9-ylmethoxycarbonyl)amino]pentanoic acid
  • N-(9H-Fluorene-9-ylmethoxycarbonyl)-5-oxo-5-tert-butoxy-L-norvaline
  • N-(9H-Fluorene-9-ylmethoxycarbonyl)-L-glutamic acid 5-tert-butyl ester
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic acid 5-(1,1-dimethylethyl) ester
  • 5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate
  • Fmoc-Glutamic acid (OtBu)-OH
  • L-GLUTAMIC ACID-N-FMOC, GAMMA-TERT-BUTYL ESTER
  • 5-tert-Butyl N-Fmoc-L-glutamate N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic Acid 5-tert-Butyl Ester Fmoc-Glu(OtBu)-OH
  • (2S)-5-tert-Butoxy-2-[[[(9H-fluoren-9-yl)Methoxy]carbonyl]aMino]-5-oxopentanoic acid
  • FMoc-L-Glu(OBu-t)-OH
  • N-(9-FluorenylMethoxycarbonyl)glutaMic acid γ-tert-butyl ester
  • N-(9-FluorenylMethoxycarbonyl)-L-glutaMic acid γ-tert-butyl ester
  • (S)-2-((((9H-fluoren-9-yl)Methoxy)carbonyl)aMino)-5-(tert-butoxy)-5-oxopentanoic acid
  • Fmoc-L-glutamic Acidγ-t-Butyl Ester
  • FMOC-L-GLU(OTBU)-OH(71989-18-9)
  • FMOC-L-GLUTAMIC ACID 5-TERT-BUTYL ESTER
  • FMOC-L-GLU(O T-BU)
  • FMOC-L-GLU(O-T-BUTYL)
  • FMOC-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
  • FMOC-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER
  • FMOC-L-GLUTAMIC ACID G-T-BUTYL ESTER
  • FMOC-L-GLUTAMIC ACID (OTBU)
  • FMOC-L-GLUTAMIC ACID(O-T-BUTYL)
  • FMOC-L-GLU(TBU)-OH
  • 9-FLUORENYLMETHOXYCARBONYL-L-GLUTAMIC ACID GAMMA-T-BUTYL ESTER
  • 5-tert-Butyl N-[(9H-fluoren-9-ylmethoxy)carbonyl]-2-aminoglutarate
  • FMOC-GLU(OTBU)-OH 98+%
  • FMOC-L-GLUTAMIC ACID-O-T-BUTYLESTER MONOHYDRATE 98%
  • Fmoc-Glu(Tbut)-Oh
  • L-Glutamic Acid-UL-13C5,15N-N-FMOC y-t-Butyl Ester
  • FMOC-GLU(TBU)-OH
  • N-9-Fluorenylmethyloxycarbonyl-L-glutamicacidg-t-butylester
  • N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-L-GLUTAMIC-ACID-GAMMA-T-BUTYL ESTER MONOHYDRATE
  • NALPHA-9-Fluorenylmethoxycarbonyl-L-glutamic acid GAMMA-tert- butyl ester
  • FMOC-L-GLUTAMIC ACID GAMMA-TERT-BUTYL ESTER (FMOC-L-GLU-OTBU-OH)
  • L-GLUTAMIC ACID, N-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-L-GLUTAMIC ACID-5-TERT-BUTYL ESTER
  • 5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate Hydrate
  • 5-tert-Butyl N-Fmoc-L-glutamate
  • N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamic Acid 5-tert-Butyl Ester
  • N<sup>α</sup>-FMoc-L-glutaMic-acid 5-tert-butyl ester
  • Fmoc-Glu(Otbu)-OH(CAS:71989-18-9)
  • Fmoc-Glu(OtBu)-OH Hydrate