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CAMPESTEROL

Product Name
CAMPESTEROL
CAS No.
474-62-4
Chemical Name
CAMPESTEROL
Synonyms
Campesterin;Ergost-5-en-3-ol;24α-methyl Cholesterol;(24R)-Ergost-5-en-3β-ol;C01789;CAMPESTROL;CAMPESTEROL;Campasterol;Mieyajunsu A;-17-((2R,5R)
CBNumber
CB9168763
Molecular Formula
C28H48O
Formula Weight
400.69
MOL File
474-62-4.mol
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CAMPESTEROL Property

Melting point:
156-160 °C
alpha 
D23 -33° (22.5 mg in 5 ml chloroform)
Boiling point:
463.29°C (rough estimate)
Density 
0.98±0.1 g/cm3 (20 ºC 760 Torr)
refractive index 
1.5100 (estimate)
storage temp. 
-20°C
solubility 
Chloroform (Sparingly), Methanol (Slightly, Sonicated)
pka
15.03±0.70(Predicted)
form 
crystalline
color 
white
Merck 
13,1736
BRN 
3216975
InChIKey
SGNBVLSWZMBQTH-ZRUUVFCLSA-N
LogP
9.972 (est)
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Safety

Hazard Codes 
Xn,T
Risk Statements 
20/21/22-36/37/38-48/20/22-40-38-22
Safety Statements 
26-36-45-36/37/39-23
RIDADR 
UN 1888 6.1/PG 3
WGK Germany 
3
HS Code 
29061990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
C5157
Product name
Campesterol
Purity
~65%
Packaging
1mg
Price
$130
Updated
2024/03/01
Sigma-Aldrich
Product number
C5157
Product name
Campesterol
Purity
~65%
Packaging
5mg
Price
$360
Updated
2024/03/01
Cayman Chemical
Product number
17344
Product name
24α-methyl Cholesterol
Purity
≥95%
Packaging
1mg
Price
$71
Updated
2023/06/20
Cayman Chemical
Product number
17344
Product name
24α-methyl Cholesterol
Purity
≥95%
Packaging
5mg
Price
$229
Updated
2023/06/20
Sigma-Aldrich
Product number
C5157
Product name
Campesterol
Purity
~65%
Packaging
10mg
Price
$599
Updated
2024/03/01
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CAMPESTEROL Chemical Properties,Usage,Production

Description

24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.

Chemical Properties

White Solid

Uses

A phytosterol, which may inhibit the intestinal absorption of cholesterol.

Uses

Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.

Definition

ChEBI: Campesterol is a member of phytosterols, a 3beta-sterol, a 3beta-hydroxy-Delta(5)-steroid and a C28-steroid. It has a role as a mouse metabolite. It derives from a hydride of a campestane.

General Description

Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.

Biochem/physiol Actions

Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.

Purification Methods

Campesterol is recrystallised twice from hexane and once from Me2CO. The benzoyl derivative has m 158-160o [] D 23 -8.6o (CHCl3), and the acetyl derivative has m 137138o (EtOH) and [] D 23 -35.1o (c 2.9, CHCl3) [Fernholz & MacPhillamy J Am Chem Soc 6 3 1155 1941]. [Beilstein 6 III 2680.]

CAMPESTEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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CAMPESTEROL Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17989
Advantage
64
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@163.com
Country
China
ProdList
284
Advantage
58
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
Fax
021-55068248
Email
shyysw007@163.com
Country
China
ProdList
4941
Advantage
60
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Fax
+86-28-82633165
Email
cwb1@biopurify.cn
Country
China
ProdList
2376
Advantage
60
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4968
Advantage
50
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9552
Advantage
55
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View Lastest Price from CAMPESTEROL manufacturers

Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
Product
Campesterol 474-62-4
Price
US $70.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
10kg
Release date
2020-06-13
Shanghai Standard Technology Co., Ltd.
Product
Campesterol 474-62-4
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2020-01-02
Hebei Zhanyao Biotechnology Co. Ltd
Product
Campesterol 474-62-4 474-62-4
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 tons
Release date
2021-10-08

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