CAMPESTEROL

Product Name: CAMPESTEROL
CAS No.: 474-62-4
Chemical Name: CAMPESTEROL
Synonyms: Campesterin;Ergost-5-en-3-ol;24α-methyl Cholesterol;(24R)-Ergost-5-en-3β-ol;C01789;CAMPESTROL;CAMPESTEROL;Campasterol;Mieyajunsu A;-17-((2R,5R)
CBNumber: CB9168763
Molecular Formula: C28H48O
Formula Weight: 400.69
MOL File: 474-62-4.mol

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CAMPESTEROL Property

Melting point:: 156-160 °C
alpha: D23 -33° (22.5 mg in 5 ml chloroform)
Boiling point:: 463.29°C (rough estimate)
Density: 0.98±0.1 g/cm3 (20 ºC 760 Torr)
refractive index: 1.5100 (estimate)
storage temp.: -20°C
solubility: Chloroform (Sparingly), Methanol (Slightly, Sonicated)
pka: 15.03±0.70(Predicted)
form: crystalline
color: white
biological source: Glycine max (soybean)
Merck: 13,1736
BRN: 3216975
InChIKey: SGNBVLSWZMBQTH-ZRUUVFCLSA-N
LogP: 9.972 (est)

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Safety

Hazard Codes: Xn,T
Risk Statements: 20/21/22-36/37/38-48/20/22-40-38-22
Safety Statements: 26-36-45-36/37/39-23
RIDADR: UN 1888 6.1/PG 3
WGK Germany: 3
HS Code: 29061990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: C5157
Product name: Campesterol
Purity: ~65%
Packaging: 1mg
Price: $130
Updated: 2024/03/01

Sigma-Aldrich

Product number: C5157
Product name: Campesterol
Purity: ~65%
Packaging: 5mg
Price: $360
Updated: 2024/03/01

Cayman Chemical

Product number: 17344
Product name: 24α-methyl Cholesterol
Purity: ≥95%
Packaging: 1mg
Price: $71
Updated: 2023/06/20

Cayman Chemical

Product number: 17344
Product name: 24α-methyl Cholesterol
Purity: ≥95%
Packaging: 5mg
Price: $229
Updated: 2023/06/20

Sigma-Aldrich

Product number: C5157
Product name: Campesterol
Purity: ~65%
Packaging: 10mg
Price: $599
Updated: 2024/03/01

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CAMPESTEROL Chemical Properties,Usage,Production

Description

24α-methyl Cholesterol is a phytosterol found in vegetables, fruits, nuts, and seeds that competitively inhibits the absorption of intestinal cholesterol and decreases the transcription of genes important for cholesterol metabolism. The cholesterol lowering effects of phytosterols, such as 24α-methyl cholesterol, have been reported to be beneficial for lowering the incidence of atherosclerotic plaques. 24α-methyl Cholesterol can also act as an agonist at liver X receptors (LXR) and, through activation of LXR signaling, has been shown to suppress the proliferation of prostate and breast cancer cells.

Chemical Properties

White Solid

Uses

A phytosterol, which may inhibit the intestinal absorption of cholesterol.

Uses

Campesterol may be used as a plant sterol to test its effect on the transcriptional activation of liver X receptor α (LXRA) in breast cancer cells. It may also be used as a sterol standard for calibration curve generation in liquid chromatography multiple reaction monitoring (LC-MRM) analysis.

Definition

ChEBI: Campesterol is a member of phytosterols, a 3beta-sterol, a 3beta-hydroxy-Delta(5)-steroid and a C28-steroid. It has a role as a mouse metabolite. It derives from a hydride of a campestane.

General Description

Campesterol is a plant sterol, which is an analog of cholesterol and a brassinosteroid (BR) precursor. The enzyme diminute/dwarf1 mediates the synthesis of campesterol from 24-methylenecholesterol. Campesterol possesses methyl group at C-24 position of the side chain in the cholesterol structure.

Biochem/physiol Actions

Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.

Purification Methods

Campesterol is recrystallised twice from hexane and once from Me2CO. The benzoyl derivative has m 158-160o [] D 23 -8.6o (CHCl3), and the acetyl derivative has m 137138o (EtOH) and [] D 23 -35.1o (c 2.9, CHCl3) [Fernholz & MacPhillamy J Am Chem Soc 6 3 1155 1941]. [Beilstein 6 III 2680.]

CAMPESTEROL Preparation Products And Raw materials

Raw materials

Preparation Products

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CAMPESTEROL Suppliers

Canada 2 China 190 Germany 1 India 4 Switzerland 1 United Kingdom 4 United States 20 Global 222

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View Lastest Price from CAMPESTEROL manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD

Product: CAMPESTEROL 474-62-4
Price: US $980.00-750.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000
Release date: 2024-08-15

Shaanxi Dideu Medichem Co. Ltd

Product: CAMPESTEROL 474-62-4
Price: US $1.00-22.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100000KG
Release date: 2024-08-02

Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.

Product: Campesterol 474-62-4
Price: US $70.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10kg
Release date: 2020-06-13

474-62-4, CAMPESTEROLRelated Search:

Campesterol,?95+％,CAMPESTEROL(P),CAMPESTEROL 1X1ML CHLOROFORM 100UG/ML beta-Sitosterol, with ca. 10% campesterol, ca. 75% beta-sitosterol,SS-SITOSTEROL: 45% (CONTAINS CAMPESTEROL),beta-Sitosterol (contains Campesterol) beta-Sitosterol Acetate (contains Campesterol) Campesterol-25,26,26,26,27,27,27-D7 CAMPESTEROL-D3 7-Campesterol Campesteryl-D-glucoside Campesteryl-D-glucoside-6’-palmitate Campesteryl palmitate Campesteryl ferulate Δ8-Campesterol 7-KETO-BETA-CAMPESTEROL 7-ALPHA-HYDROXY-BETA-CAMPESTEROL Campesterol (24-methyl-D3) DELTA7-CAMPESTEROL campesterol acetate 5,6-DIHYDROXY-BETA-CAMPESTEROL 5,6-ALPHA/BETA-EPOXY-BETA-CAMPESTEROL

(24R)-5-Ergosten-3beta-ol

(24R)-Methylcholest-5-en-3beta-ol

24alpha-Methylcholesterol

Campesterin

DELTA5-24-Isoergosten-3beta-ol

Ergost-5-en-3beta-ol, (24R)-

Ergost-5-en-3-ol

Ergost-5-en-3-ol, (3beta,24R)-

ERGOST-5-EN-3-BETA-OL

ERGOST-5-EN-3B-OL

CAMPESTEROL

CAMPESTROL

5-CHOLESTEN-24-ALPHA-METHYL 3-BETA-OL

5-CHOLESTEN-24A-METHYL-3BETA-OL

5-CHOLESTEN-24A-METHYL-3B-OL

24ALPHA-METHYL-5-CHOLESTEN-3BETA-OL

24(R)-ERGOST-5-EN-3BETA-OL

Campesterol from Glycine max (soybean)

campesterol from soybean

24α-methyl-5-cholesten-3β-ol

17-(5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

24α-Methyl-5-cholesten-3β-ol, 24(R)-Ergost-5-en-3β-ol

Campesterol solution

(24R)-24-Methylcholest-5-en-3β-ol

(24R)-24-Methylcholesterol

(24R)-Ergost-5-en-3β-ol

Δ5-Campesterol

C01789

Campesterol,24α-Methyl-5-cholesten-3β-ol, 24(R)-Ergost-5-en-3β-ol

CaMpesterol, froM Brassica caMpestris L.

5-Cholesten-24(RS)-Methyl-3-ol-d7

CaMpest-5-en-3-ol

Mieyajunsu A

Campasterol

Campesterol, 98%, from Brassica campestris L.

Ergost-5-en-3-ol, (3,24R)-

Campesterol, >=98%

(8R,9S,10S,13R,14S,17R)

-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

-17-((2R,5R)

-5,6-Dimethylheptan-2-yl)

(24R)-5-ERGOSTEN-3Β-OL

(3S,8S,9S,10R,13R,14S,17R)-17-((2R,5R)-5,6-dimethylheptan-2-yl)-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-ol

24α-methyl Cholesterol

Campesterol 474-62-4

first-classCampesterol

CampesterolQ: What is Campesterol Q: What is the CAS Number of Campesterol Q: What is the storage condition of Campesterol Q: What are the applications of Campesterol

(24R)-5-Ergosten-3β-ol

Campesterol (6CI)

5-Cholesten-24α-methyl 3β-ol

Ergost-5-en-3-ol, (3β,24R)-

Canola sterol

Campesterol-RM

24(R)-Methylcholesterol

Ergost-5-En-3β-Ol

474-62-4

C28H41D7O

BioChemical