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3-Hydroxy-4-methoxycinnamic acid

Product Name
3-Hydroxy-4-methoxycinnamic acid
CAS No.
537-73-5
Chemical Name
3-Hydroxy-4-methoxycinnamic acid
Synonyms
ISOFERULIC ACID;(E)-3-(3-hydroxy-4-Methoxyphenyl)acrylic acid;Isoferulic;HESPERETIC ACID;Hesperetate;Isoferulate;Isoferulic Aci;HESPERETINIC ACID;AKOS BBS-00006960;Hesperitinic acid
CBNumber
CB9178579
Molecular Formula
C10H10O4
Formula Weight
194.18
MOL File
537-73-5.mol
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3-Hydroxy-4-methoxycinnamic acid Property

Melting point:
230 °C (dec.)(lit.)
Boiling point:
250.62°C (rough estimate)
Density 
1.0583 (rough estimate)
refractive index 
1.5168 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in ethanol and methanol.
pka
4.53±0.10(Predicted)
form 
Solid
color 
Pale Yellow
BRN 
2212760
LogP
0.788 (est)
CAS DataBase Reference
537-73-5(CAS DataBase Reference)
NIST Chemistry Reference
Cinnamic acid, 3-hydroxy-4-methoxy-(537-73-5)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-24/25
WGK Germany 
2
RTECS 
UD3365400
Hazard Note 
Irritant
HS Code 
29189090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
103012
Product name
3-Hydroxy-4-methoxycinnamic acid, predominantly trans
Purity
97%
Packaging
1g
Price
$41.5
Updated
2024/03/01
Sigma-Aldrich
Product number
103012
Product name
3-Hydroxy-4-methoxycinnamic acid, predominantly trans
Purity
97%
Packaging
5g
Price
$198
Updated
2024/03/01
TCI Chemical
Product number
H0524
Product name
3-Hydroxy-4-methoxycinnamic Acid
Purity
>98.0%(T)(HPLC)
Packaging
1g
Price
$56
Updated
2024/03/01
TCI Chemical
Product number
H0524
Product name
3-Hydroxy-4-methoxycinnamic Acid
Purity
>98.0%(T)(HPLC)
Packaging
5g
Price
$220
Updated
2024/03/01
Alfa Aesar
Product number
A10482
Product name
3-Hydroxy-4-methoxycinnamic acid, predominantly trans, 98+%
Packaging
1g
Price
$33.65
Updated
2024/03/01
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3-Hydroxy-4-methoxycinnamic acid Chemical Properties,Usage,Production

Chemical Properties

Off-White Crystalline Solid

Uses

3-Hydroxy-4-methoxycinnamic Acid (Isoferulic acid) is a hypoglycemic agent.

Uses

3-Hydroxy-4-methoxycinnamic acid exhibits hypoglycemic properties.

Uses

3-Hydroxy-4-methoxycinnamic acid was used in the synthesis of tranilast and various tranilast analogs (cinnamoyl anthranilates) by genetically engineered Saccharomyces cerevisiae yeast strain. It was also used in the synthesis of glycoside compounds by undergoing glycosidation.

Definition

ChEBI: A ferulic acid consisting of trans-cinnamic acid bearing methoxy and hydroxy substituents at positions 4 and 3 respectively on the phenyl ring.

General Description

3-Hydroxy-4-methoxycinnamic acid, predominantly trans is available as white crystals. 3-Hydroxy-4-methoxycinnamic acid is isolated from the aerial part of Artemisia capillaris, Chinese medicinal plant. It is a component of chinese herbal medicine used for a pain killer and stomachic. It is an efficient acetylcholine inhibitor. 3-Hydroxy-4-methoxycinnamic acid is bioactive metabolite of Spilanthes acmella Murr. It increases the resistance of low-density lipoprotein (LDL) to oxidation.

3-Hydroxy-4-methoxycinnamic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Hydroxy-4-methoxycinnamic acid Suppliers

Tianjin Wizard Science and Technology Co., Ltd.
Tel
22-22-58620773 18102163693
Fax
86-22-58620773
Email
tjchemwizard@163.com
Country
China
ProdList
97
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J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
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Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
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61
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
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TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
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81
Energy Chemical
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021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
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Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
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ShengXiong Biological Technology Development Co., Ltd.
Tel
86-021-64960112 13774219177
Fax
86-021-64960112
Email
alpha9196@gmail.com
Country
China
ProdList
52
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
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64
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View Lastest Price from 3-Hydroxy-4-methoxycinnamic acid manufacturers

Hebei Dangtong Import and export Co LTD
Product
3-Hydroxy-4-methoxycinnamic acid 537-73-5
Price
US $456.00-440.00/kilograms
Min. Order
10kilograms
Purity
99%
Supply Ability
100tons
Release date
2023-02-16
Hebei Duling International Trade Co. LTD
Product
3-Hydroxy-4-methoxycinnamic acid 537-73-5
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000 Ton
Release date
2022-10-11
Hebei Fengqiang Trading Co., LTD
Product
3-Hydroxy-4-methoxycinnamic acid 537-73-5
Price
US $100.00/bag
Min. Order
1bag
Purity
99
Supply Ability
5000
Release date
2023-09-14

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