3-Indoleacrylic acid

Product Name: 3-Indoleacrylic acid
CAS No.: 1204-06-4
Chemical Name: 3-Indoleacrylic acid
Synonyms: INDOLE-3-ACRYLIC ACID;INDOLE ACRYLIC ACID;BETA-INDOLEACRYLIC ACID;TRANS-INDOLE-3-ACRYLIC ACID;Indol-acrylate;3-Indoleacrylic;Indole-3-Acrylic;RARECHEM BK HD 0025;TIMTEC-BB SBB003692;Indoleacrylicacid97%
CBNumber: CB9202186
Molecular Formula: C11H9NO2
Formula Weight: 187.19
MOL File: 1204-06-4.mol

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3-Indoleacrylic acid Property

Melting point:: 185 °C (dec.)(lit.)
Boiling point:: 321.94°C (rough estimate)
Density: 1.1963 (rough estimate)
refractive index: 1.4900 (estimate)
storage temp.: room temp
form: powder
pka: 4.59±0.10(Predicted)
color: white to light yellow
Water Solubility: freely soluble
BRN: 6317
CAS DataBase Reference: 1204-06-4(CAS DataBase Reference)
EPA Substance Registry System: 2-Propenoic acid, 3-(1H-indol-3-yl)- (1204-06-4)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
RTECS: NL3680000
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I1625
Product name: 3-Indoleacrylic acid
Purity: powder
Packaging: 5g
Price: $231
Updated: 2024/03/01

Sigma-Aldrich

Product number: I1625
Product name: 3-Indoleacrylic acid
Purity: powder
Packaging: 10g
Price: $407
Updated: 2024/03/01

TCI Chemical

Product number: I0025
Product name: 3-Indoleacrylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $66
Updated: 2024/03/01

TCI Chemical

Product number: I0025
Product name: 3-Indoleacrylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $195
Updated: 2024/03/01

Sigma-Aldrich

Product number: I2273
Product name: 3-Indoleacrylic acid
Purity: BioReagent, ≥98% (HPLC)
Packaging: 1g
Price: $92
Updated: 2024/03/01

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3-Indoleacrylic acid Chemical Properties,Usage,Production

Chemical Properties

light yellow to yellow-beige crystalline powder

Uses

3-Indoleacrylic acid has been used in the induction of ribokinase expression in E. coli.

Definition

ChEBI: (E)-3-(indol-3-yl)acrylic acid is an alpha,beta-unsaturated monocarboxylic acid that is acrylic acid in which one of the hydrogens at position 3 is replaced by an indol-3-yl group. It is an alpha,beta-unsaturated monocarboxylic acid and a member of indoles. It is functionally related to an acrylic acid. It is a conjugate acid of an (E)-3-(indol-3-yl)acrylate(1-).

Synthesis Reference(s)

Synthesis, p. 236, 1984 DOI: 10.1055/s-1984-30787

General Description

3-Indoleacrylic acid (IAA) is a chemical used for the induction of gene transcription. This expression system requires that the gene of interest is cloned in plasmids containing the trpE promoter.

Biochem/physiol Actions

3-Indoleacrylic acid helps to block the mycelial growth of?Neurospora crassa. As a result, the cells accumulate indoleglycerol phosphate, which influences the rate of tryptophan synthetase.

Purification Methods

Recrystallise the acid from AcOH, H2O or EtOAc/cyclohexane. UV in MeOH has at 225, 274 and 325nm. [Shaw et al. J Org Chem 23 1171 1958, constitution: Rappe Acta max Chem Scand 18 818 1964, Moffatt J Chem Soc 1442 1957, Kimming et al. Hoppe Seyler's Z Physiol Chem 371 234 1958, Beilstein 22 V 249.]

3-Indoleacrylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Indoleacrylic acid Suppliers

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View Lastest Price from 3-Indoleacrylic acid manufacturers

Shijiazhuang Gantuo Biotechnology Co., Ltd

Product: 3-Indoleacrylic acid 1204-06-4
Price: US $99.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 tons
Release date: 2021-04-26

Hebei Zhanyao Biotechnology Co. Ltd

Product: 3-Indoleacrylic acid 1204-06-4
Price: US $20.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: Above 99%
Supply Ability: 5000kg/month
Release date: 2021-03-05

Career Henan Chemical Co

Product: 3-Indoleacrylic acid 1204-06-4
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 1000kg
Release date: 2018-12-25

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C11H9NO2

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