5-Bromo-1,3-benzenediol
- Product Name
- 5-Bromo-1,3-benzenediol
- CAS No.
- 106120-04-1
- Chemical Name
- 5-Bromo-1,3-benzenediol
- Synonyms
- Phloroglucinol Impurity;5-BroMoresorcinol;5-BroMo-benzene-1,3-diol;5-Bromoresorcino;5-Bromoresorcinol>5-Bromo-1,3-benzenediol;1,3-Benzenediol, 5-bromo-;3,5-DihydroxybroMobenzene;Phloroglucinol Impurity 14;1-Bromo-3,5-dihydroxybenzene
- CBNumber
- CB92103634
- Molecular Formula
- C6H5BrO2
- Formula Weight
- 189.01
- MOL File
- 106120-04-1.mol
5-Bromo-1,3-benzenediol Property
- Melting point:
- 90.0 to 95.0 °C
- Boiling point:
- 140°C/0.3mmHg(lit.)
- Density
- 1.844±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- powder to crystal
- pka
- 8.49±0.10(Predicted)
- color
- White to Almost white
Safety
- HS Code
- 29089990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- B3731
- Product name
- 5-Bromoresorcinol
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $137
- Updated
- 2025/07/31
- Product number
- B3731
- Product name
- 5-Bromoresorcinol
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $479
- Updated
- 2025/07/31
- Product number
- D679043
- Product name
- 3,5-Dihydroxybromobenzene
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- FD149366
- Product name
- 3,5-Dihydroxybromobenzene
- Packaging
- 1g
- Price
- $180
- Updated
- 2021/12/16
- Product number
- 1394AA
- Product name
- 5-Bromobenzene-1,3-diol
- Packaging
- 5g
- Price
- $276
- Updated
- 2021/12/16
5-Bromo-1,3-benzenediol Chemical Properties,Usage,Production
Acquired resistance
5-Bromobenzene-1,3-diol is used in the synthesis of antimicrobial compounds, resorcinol derivatives and polycyclic compounds.
Synthesis
20469-65-2
106120-04-1
The general procedure for the synthesis of 5-bromo-1,3-benzenediol from 1-bromo-3,5-dimethoxybenzene was as follows: in Example 24, compound (35) (15.0 g, 69.0 mmol) was dissolved in dichloromethane (40 mL) and cooled to 0°C. A 1 M solution of boron tribromide in dichloromethane (140 mL, 140 mmol) was slowly added, keeping the reaction mixture in an ice bath. After dropwise addition, the reaction mixture was stirred at room temperature for 18 hours. Upon completion of the reaction, the reaction was quenched with methanol and the reaction mixture was subsequently concentrated. The residue was dissolved in ethyl acetate (500 mL) and washed with deionized water (300 mL). The organic layer was separated, dried over anhydrous sodium sulfate and concentrated to give the target product 5-bromo-1,3-benzenediol (45) (13.03 g, yield >99%) as an orange oil.
References
[1] Patent: US2011/136802, 2011, A1. Location in patent: Page/Page column 26-27
[2] Journal of the American Chemical Society, 2014, vol. 136, # 6, p. 2220 - 2223
[3] Patent: WO2014/60431, 2014, A1. Location in patent: Page/Page column 105
[4] Angewandte Chemie - International Edition, 2009, vol. 48, # 7, p. 1283 - 1286
[5] European Journal of Medicinal Chemistry, 2009, vol. 44, # 7, p. 2765 - 2775
5-Bromo-1,3-benzenediol Preparation Products And Raw materials
Raw materials
Preparation Products
5-Bromo-1,3-benzenediol Suppliers
- Tel
- 800-4238616
- Fax
- +1-888-520-1075 / +1-503-283-1987
- sales@tciamerica.com
- Country
- Americas
- ProdList
- 23653
- Advantage
- 75
View Lastest Price from 5-Bromo-1,3-benzenediol manufacturers
- Product
- 5-Bromo-1,3-benzenediol 106120-04-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
- Product
- 5-Bromo-1,3-benzenediol 106120-04-1
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-11