DCPIB

Product Name: DCPIB
CAS No.: 82749-70-0
Chemical Name: DCPIB
Synonyms: DCPIB;4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID;4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid;4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid;4-((2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)butanoic acid;4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID;Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-;Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO
CBNumber: CB9215009
Molecular Formula: C22H28Cl2O4
Formula Weight: 427.36
MOL File: 82749-70-0.mol

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DCPIB Property

Boiling point:: 593.8±50.0 °C(Predicted)
Density: 1.262±0.06 g/cm3(Predicted)
storage temp.: Store at +4°C
solubility: insoluble in H2O; ≥49.8 mg/mL in EtOH; ≥50.8 mg/mL in DMSO
form: solid
pka: 4.53±0.10(Predicted)
color: White

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Safety

Hazard Codes: T
Risk Statements: 25-41
Safety Statements: 26-36/39-45

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H318Causes serious eye damage

H413May cause long lasting harmful effects to aquatic life

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris

Product number: 1540
Product name: DCPIB
Purity: ≥98%(HPLC)
Packaging: 50
Price: $675
Updated: 2021/12/16

Tocris

Product number: 1540
Product name: DCPIB
Purity: ≥98%(HPLC)
Packaging: 10
Price: $160
Updated: 2021/12/16

TRC

Product number: D195150
Product name: DCPIB
Packaging: 100mg
Price: $1105
Updated: 2021/12/16

Usbiological

Product number: 255115
Product name: DCPIB
Packaging: 10mg
Price: $403
Updated: 2021/12/16

ChemScene

Product number: CS-0027766
Product name: DCPIB
Purity: 99.81%
Packaging: 50mg
Price: $550
Updated: 2021/12/16

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DCPIB Chemical Properties,Usage,Production

Uses

DCPIB is a potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β-cells.

Definition

ChEBI: 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-1-oxo-3H-inden-5-yl)oxy]butanoic acid is a member of indanones.

Biological Activity

Potent, selective blocker of the volume-sensitive anion channel (VSAC) in rat pancreatic β -cells (IC 50 ~ 2 μ M) and I Cl,swell in various cardiovascular tissues (IC 50 = 4.1 μ M in CPAE cells); blockade is voltage-independent. Displays minimal inhibition of other Cl - and K + currents (< 10% inhibition at 10 μ M). Inhibits glucose-stimulated insulin secretion in intact β -cells via VSAC inhibition and indirect K ATP channel activation. Reverses cell swelling-induced action potential duration shortening in atrial myocytes and inhibits astroglial swelling in vitro .

storage

Store at +4°C

DCPIB Preparation Products And Raw materials

Raw materials

Preparation Products

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DCPIB Suppliers

China 44 Germany 2 Switzerland 1 United Kingdom 2 United States 11 Global 60

EMMX Biotechnology LLC

Tel: 888-539-0666
Fax: 888-539-0666
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Country: United States
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
Advantage: 58

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
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Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
Country: United States
ProdList: 17982
Advantage: 58

BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19553
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TargetMol Chemicals Inc.

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Country: United States
ProdList: 38631
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Aladdin Scientific

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Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
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ApexBio Technology

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Cayman Chemical Company

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Country: United States
ProdList: 6213
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MedChemExpress

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Country: United States
ProdList: 6398
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Riedel-de Haen AG

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ProdList: 6773
Advantage: 87

82749-70-0, DCPIBRelated Search:

2,3-Dichloro-4-hydroxybenzaldehyde 6-CHLORO-1-INDANONE 96 7-CHLORO-1-INDANONE 2-CHLORO-4,5-DIMETHYLPHENOL 4-(3-CHLORO-PHENOXY)-BUTYRIC ACID 2'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2',3'-DICHLORO-2,2-DIMETHYLBUTYROPHENONE 2-PENTYL-1-INDANONE 1-(3-chloro-4-ethoxyphenyl)ethanone DCPIB 1-(3-CHLORO-4-PROPOXYPHENYL)-ETHANONE 3'-CHLORO-2,2-DIMETHYLBUTYROPHENONE 2'-CHLORO-2,2-DIMETHYLPROPIOPHENONE 2',3'-DICHLORO-2,2-DIMETHYLPROPIOPHENONE 2,2-DIMETHYL-4'-METHOXYBUTYROPHENONE 4-(4-ACETYL-PHENOXY)-BUTYRIC ACID 1-(4-methoxyphenyl)-2,2-dimethyl-propan-1-one 3'-CHLORO-2,2-DIMETHYLPROPIOPHENONE

DCPIB

4-[(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYL-2,3-DIHYDRO-1-OXO-1H-INDEN-5-YL)OXY]BUTANOIC ACID

4-(2-BUTYL-6,7-DICHLORO-2-CYCLOPENTYLINDAN-1-ON-5-YL)OXYBUTYRIC ACID

Butanoic acid, 4-[(2-butyl-6,7-dichloro-2-cyclopentyl-2,3-dihydro-1-oxo-1H-inden-5-yl)oxy]-

Cl-Channels,Chloride Channel,cardiomyocytes,DCPIB,ischemia,COS-7,KcsA,Potassium Channel,CPAE cell,Inhibitor,inhibit,swelling,rMCAO

4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid

4-[(2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-5-indanyl)oxy]butanoic Acid

4-((2-Butyl-6,7-dichloro-2-cyclopentyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy)butanoic acid

82749-70-0

Chloride channel