ChemicalBook > CAS DataBase List > 6-Azauracil

6-Azauracil

Product Name
6-Azauracil
CAS No.
461-89-2
Chemical Name
6-Azauracil
Synonyms
1,2,4-TRIAZINE-3,5(2H,4H)-DIONE;1,2,4-triazine-3,5-diol;Azauracil;AZU;6-AU;ipo3834;nsc3425;NSC 3425;IPO 3834;USAF cb-30
CBNumber
CB9223189
Molecular Formula
C3H3N3O2
Formula Weight
113.07
MOL File
461-89-2.mol
More
Less

6-Azauracil Property

Melting point:
274-275 °C(lit.)
Boiling point:
211.75°C (rough estimate)
Density 
1.5988 (rough estimate)
refractive index 
1.4264 (estimate)
storage temp. 
Store below +30°C.
solubility 
1 M NH4OH: 50mg/mL, clear to slightly hazy, colorless to light yellow-green
pka
7.78±0.20(Predicted)
form 
Fine Crystalline Powder
color 
White to light yellow
Water Solubility 
Partly soluble in water, ethanol, DMSO, and 1 M NH4OH (50 mg/ml).
BRN 
116472
InChI
InChI=1S/C3H3N3O2/c7-2-1-4-6-3(8)5-2/h1H,(H2,5,6,7,8)
InChIKey
SSPYSWLZOPCOLO-UHFFFAOYSA-N
SMILES
N1=CC(=O)NC(=O)N1
CAS DataBase Reference
461-89-2(CAS DataBase Reference)
NIST Chemistry Reference
1,2,4-Triazine-3,5(2H,4H)-dione(461-89-2)
EPA Substance Registry System
1,2,4-Triazine-3,5(2H,4H)-dione (461-89-2)
More
Less

Safety

Hazard Codes 
Xi,T
Risk Statements 
36/37/38-63-25
Safety Statements 
26-36-45-38-36/37/39
WGK Germany 
3
RTECS 
XY7700000
F 
10-23
TSCA 
Yes
HazardClass 
IRRITANT
HS Code 
29336980
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.41156
Product name
6-Azauracil
Purity
for synthesis
Packaging
5G
Price
$85.8
Updated
2024/03/01
Sigma-Aldrich
Product number
A1757
Product name
6-Azauracil
Purity
≥98%
Packaging
5g
Price
$95.2
Updated
2024/03/01
Sigma-Aldrich
Product number
8.41156
Product name
6-Azauracil
Purity
for synthesis
Packaging
25g
Price
$424
Updated
2024/03/01
TCI Chemical
Product number
A0558
Product name
6-Azauracil
Purity
>99.0%(HPLC)(T)
Packaging
1g
Price
$19
Updated
2024/03/01
TCI Chemical
Product number
A0558
Product name
6-Azauracil
Purity
>99.0%(HPLC)(T)
Packaging
5g
Price
$53
Updated
2024/03/01
More
Less

6-Azauracil Chemical Properties,Usage,Production

Chemical Properties

white to light yellow fine crystalline powder

Uses

6-Azauracil (6-AU) is used as a growth inhibitor of various microorganisms via depletion of intracellular GTP and UTP nucleotide pools. 6-Azauracil has been widely used in investigations on modulation of transcription, especially in yeast models.

Definition

ChEBI: 6-azauracil is a 1,2,4-triazine compound having oxo-substituents at the 3- and 5-positions. It has a role as an antimetabolite. It is a member of 1,2,4-triazines and a nucleobase analogue.

Synthesis Reference(s)

The Journal of Organic Chemistry, 23, p. 1522, 1958 DOI: 10.1021/jo01104a033

Biochem/physiol Actions

6-Azauracil (6-AU) is a pyrimidine analog of uracil and exhibits antitumor activity. It inhibits the growth of various microorganisms by depleting intracellular guanosine triphosphate (GTP)?and uridine?triphosphate (UTP) nucleotide pools.

Safety Profile

Poison by intraperitoneal route. Experimental reproductive effects. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of NOx.

Mode of action

6-Azauracil is a growth inhibitor effective on a variety of microorganisms. It functions by depleting the intracellular GTP and UTP nucleotide supply. Mutations in transcriptional elongation machinery, as well as mutations in a variety of other pathways, exaggerate the growth defect of cells in the presence of 6 AU.

6-Azauracil Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

6-Azauracil Suppliers

Americas 1 Belgium 3 China 201 Europe 3 France 2 Germany 10 India 4 Japan 4 South Korea 1 Sweden 1 Switzerland 4 The Netherlands 1 United Kingdom 14 United States 44 Global 293
ITIC MEDCHEM(SUZHOU) CO.,LTD.
Tel
0512-68323967 18015559028
Fax
+86-512-69200360
Email
sales@iticmedchem.com
Country
China
ProdList
449
Advantage
61
Hebei Fanbo Pharmaceutical Technology Co., Ltd.
Tel
0531-88163906 15588346797
Email
fanbomedical@163.com
Country
China
ProdList
540
Advantage
58
Chongqing Longsheng Pharmaceutical Co., Ltd
Tel
17791355738
Email
sales@cqlonghoo.com
Country
China
ProdList
86
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94657
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12386
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9510
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9810
Advantage
59
Nanjing Chemlin Chemical Co., Ltd
Tel
19951945301
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19185
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
Suzhou Ryan Pharmaceutical Technology Co., Ltd.
Tel
0512-68780025 18962125825
Email
sales@ryanchem.com
Country
China
ProdList
170
Advantage
62
Shandong Xiya Chemical Co., Ltd
Tel
4009903999 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18738
Advantage
57
Tangshan Moneide Trading Co., Ltd.
Tel
0315-8309571 15633399667
Fax
+86-315-7726572
Email
sales@moneidechem.com
Country
China
ProdList
704
Advantage
57
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14435
Advantage
57
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Tongchuang Pharma(Suzhou). Co., Ltd.
Tel
0512-63263366 18912765016
Fax
0512-6326 3366
Email
tongtf110@sina.com
Country
China
ProdList
979
Advantage
62
Suzhou Sibian Chemical Technology Co.,Ltd.
Tel
0512-65617459 18915409046
Fax
0512-65617459
Email
sales@sibian-chem.com
Country
China
ProdList
1922
Advantage
55
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9347
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 18021050169
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Shanghai Raise Chemical Technology Co.,Ltd
Tel
+86-021-50935922
Fax
+86-021-33847795
Country
China
ProdList
7865
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Shanghai JONLN Reagent Co., Ltd.
Tel
400-0066400 13621662912
Fax
021-55660885
Email
422131432@qq.com
Country
China
ProdList
9978
Advantage
55
Huainan Kedi Chemical Factory
Tel
0554-2106669
Fax
0554-2666215
Email
sales1@kedichem.com
Country
China
ProdList
4924
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9349
Advantage
58
Modachem Shanghai Co., Ltd
Tel
+86 (0)21 51320687 51371369 1744605818
Fax
+86 (0)21 51371369
Country
China
ProdList
1578
Advantage
58
Shanghai AQBioPharma Co., Ltd.
Tel
13661411401
Fax
51370935-8011
Email
yinglv.que@aqbiopharma.com.cn
Country
China
ProdList
2810
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4943
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
SHANGHAI BANGCHENG CHEMICAL Co.,Ltd.
Tel
021-69106960 13701823733
Fax
021-69106780
Email
13701823733@163.com
Country
China
ProdList
4772
Advantage
60
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
11662
Advantage
59
Shanghai Na Qian Chemical Technology Co. Ltd.
Tel
0373-7129549; 13598610367
Fax
QQ:2468833170
Email
2841375912@qq.com
Country
China
ProdList
2727
Advantage
52
Beijing Xinsavi Chemical Technology Co., Ltd.
Tel
010-56218822 13717722232
Fax
010-56218800
Email
xinsavichem@163.com
Country
China
ProdList
3201
Advantage
56
Beijing Holiyang Chemical Co. Ltd.
Tel
13718199399
Fax
QQ : 206661479
Email
holiyangchem@163.com
Country
China
ProdList
3381
Advantage
56
Shanghai YouPeng Chemical Co. Ltd.
Tel
021-69005955 13701776567
Fax
021-69005775
Email
youpengchem@163.com
Country
China
ProdList
4295
Advantage
56
Sichuan Hainuowei Technology Co. Ltd.
Tel
13708085536
Fax
QQ : 121102042
Email
hanovichem@163.com
Country
China
ProdList
3383
Advantage
56
Shanghai TongYuan Chemical Co., Ltd.
Tel
021-021-69182866 13701855675
Fax
021-69182022
Email
tongyuanchem@126.com
Country
China
ProdList
4321
Advantage
58
More
Less

View Lastest Price from 6-Azauracil manufacturers

Suzhou Ryan Pharmachem Technology Co.,Ltd.
Product
6-Azauracil 461-89-2
Price
US $0.00/kg
Min. Order
10kg
Purity
98%
Supply Ability
kg grade
Release date
2023-05-10
Unipharm pharmaceutical industry Co., Ltd
Product
6-Azauracil 461-89-2
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2023-03-23
Shaanxi Dideu Medichem Co. Ltd
Product
6-Azauracil 461-89-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20T
Release date
2020-05-14

461-89-2, 6-AzauracilRelated Search:

Sulfadiazine 1,3,5-Triazine Hexazinone Solvent Red 43 Metribuzin Buprofezin 5-BROMO-6-AZAURACIL ,97%,5-BROMO-6-AZAURACIL 6-AZAURACIL RIBOSIDE,6-azauracil-beta-d-ribosid 5-Methyl-6-azauracil AZAURACIL, 5-(RG) 5-METHYLMERCAPTO-6-AZAURACIL,5-(METHYLTHIO)-6-AZAURACIL AZAURACIL, 6- 5-MERCAPTO-6-AZAURACIL SODIUM SALT 5-HYDRAZINO-6-AZAURACIL 5-AZAURACIL, MONOHYDRATE 5-N-MORPHOLINO-6-AZAURACIL AZAURACIL, 5-,5-AZAURACIL 6-Azauracil

  • 4(6)-Azauracil
  • As-Triazine-3,5(2H,4H)-dione
  • As-Triazine-3,5-diol
  • Azauracil
  • AZU
  • IPO 3834
  • ipo3834
  • NSC 3425
  • nsc3425
  • s-Triazine-3,5(2H,4H)-dione
  • USAF cb-30
  • TIMTEC-BB SBB004317
  • AZAURACIL, 6-
  • 6-AZA-2,4-DIHYDROXYPYRIMIDINE
  • 6-AZAURACIL
  • 3,5-DIHYDROXY-1,2,4-TRIAZINE
  • 1,2,4-triazine-3,5-diol
  • 2H,4H-AS-TRIAZINE-3,5-DIONE
  • 1,2,4-TRIAZINE-3,5-DIONE
  • 1,2,4-TRIAZINE-3,5(2H,4H)-DIONE
  • 6-AZAURACIL CRYSTALLINE
  • 6-AZAURACIL 99%
  • 6-Azauracil,98%
  • 6-AZAURAZIL
  • 6-azauridine 6-Azauracil
  • AZAURACIL, 6-(RG)
  • S-TRIAZINE-3,5-DIONE
  • 3,5-DIOXO-[1,2,4]TRIAZINE
  • 1,2,4-Triazine-3,5(2H,4H)
  • 1,2,4-Triazine-3,5(2H,4H)-dione, 3,5-Dihydroxy-1,2,4-triazine, 6-Aza-2,4-dihydroxypyrimidine
  • 2,3,4,5-Tetrahydro-1,2,4-triazine-3,5-dione
  • 6-Azauracil,99%
  • 2H-1,2,4-triazine-3,5-dione
  • 2H-1,2,4-triazine-3,5-quinone
  • as-Triazine-3,5(2H,4H)-dione (8CI)
  • WLN: T6NMVMVJ
  • 6 - nitrogen iMpurity uracil
  • 6-AU
  • 6-Azauracil &gt
  • 1,2,4-Triazine-3,5(2H,4H)-dione (9CI, ACI)
  • 461-89-2
  • BioChemical
  • Biochemicals and Reagents
  • Nucleosides, Nucleotides, Oligonucleotides
  • Nucleoside Analogs
  • Biochemistry
  • Nucleobases and their analogs
  • Nucleosides, Nucleotides & Related Reagents
  • Nucleic acids
  • Pyridines, Pyrimidines, Purines and Pteredines