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Carbazochrome

Product Name
Carbazochrome
CAS No.
69-81-8
Chemical Name
Carbazochrome
Synonyms
ADRENOCHROME MONOSEMICARBAZONE;carbazochrom;ADENOCHROME SEMICARBAZONE;ADRENOCHROME SEMICARBAZONE;adchnon;adrezon;adroxon;Kabaklo;CROMOSIL;adedolon
CBNumber
CB9231153
Molecular Formula
C10H12N4O3
Formula Weight
236.23
MOL File
69-81-8.mol
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Carbazochrome Property

Melting point:
203° (dec)
Density 
1.63±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
solubility 
DMSO (Slightly), Water (Slightly, Heated)
pka
12.38±0.40(Predicted)
form 
Solid
color 
Dark Orange to Very Dark Orange
Water Solubility 
Water: 5 mg/mL (21.17 mM; ultrasonic and adjust pH to 12 with NaOH)
Merck 
14,172
Stability:
Hygroscopic
CAS DataBase Reference
69-81-8(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
2
RTECS 
NM1925500
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
A0176
Product name
Carbazochrome
Purity
>99.0%(HPLC)
Packaging
5g
Price
$22
Updated
2024/03/01
TCI Chemical
Product number
A0176
Product name
Carbazochrome
Purity
>99.0%(HPLC)
Packaging
25g
Price
$59
Updated
2024/03/01
TRC
Product number
C175820
Product name
Carbazochrome
Packaging
25g
Price
$135
Updated
2021/12/16
AK Scientific
Product number
J11690
Product name
Carbazochrome
Packaging
100mg
Price
$39
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA70002
Product name
Adrenochrome semicarbazone
Packaging
25g
Price
$80
Updated
2021/12/16
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Carbazochrome Chemical Properties,Usage,Production

Originator

Adrenosem,Beecham,US,1953

Uses

Carbazochrome is an oxidation product of Epinephrine [E588580]) that improves microcirculatory tone. Derivatives such as carbazochrome salicylate and carbazochrome sodium sulfonate, are used as hemostats and treatment to prevent dengue shock syndrome, respectively.

Definition

ChEBI: Carbazochrome is a member of indoles. It is functionally related to a semicarbazide.

Manufacturing Process

A suspension containing 1 part by weight of adrenalin and 2 to 6 parts by weight of silver oxide in 150 to 250 parts by weight of methanol or ethanol is stirred for about 10 minutes. The alcoholic adrenochrome solution obtained is separated by draining and the filtrate is quickly evaporated to dryness at low temperature and in vacuo. The red crystals of adrenochrome obtained are dissolved in 45 to 55 parts by weight of water. To this solution, 2 parts of sodium acetate dissolved in 2 to 3 parts of water and 2 parts of semicarbazide hydrochloride dissolved in 2 to 3 parts of water are added. The formed precipitate consisting of red-orange prismatic needles is separated by filtration and recrystallized from diluted ethanol. There is obtained 0.30 to 0.40 part by weight of adrenochrome monosemicarbazone dihydrate, melting at 203°C with decomposition.

Therapeutic Function

Hemostatic

Carbazochrome Preparation Products And Raw materials

Raw materials

Preparation Products

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Carbazochrome Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
Sanwa Chemical Industry Co., Ltd.
Tel
--
Fax
--
Email
ssanwa@carbide.co.jp
Country
Japan
ProdList
9
Advantage
58
Wako Pure Chemical Industries, Ltd.
Tel
--
Fax
--
Email
labchem-tec@wako-chem.co.jp
Country
Japan
ProdList
6819
Advantage
80
Junsei Chemical Co., Ltd.
Tel
--
Fax
--
Email
shiyaku@junsei.co.jp
Country
Japan
ProdList
3096
Advantage
46
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View Lastest Price from Carbazochrome manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Carbazochrome 69-81-8
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-25
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Carbazochrome 69-81-8
Price
US $0.00-0.00/g
Min. Order
100g
Purity
99.7
Supply Ability
100kg
Release date
2024-05-14
Apeloa production Co.,Limited
Product
Carbazochrome 69-81-8
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
10000
Release date
2024-06-03

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