Outline Chemical Properties Uses Reaction of binary biuret Production method
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Biuret

Outline Chemical Properties Uses Reaction of binary biuret Production method
Product Name
Biuret
CAS No.
108-19-0
Chemical Name
Biuret
Synonyms
L-101;iuret;BIURET;BiuretGr;Isobiuret;Biuret,98%;Biuret >Biuret, 97+%;CARBAMYLUREA;CARBAMOYLUREA
CBNumber
CB8460994
Molecular Formula
C2H5N3O2
Formula Weight
103.08
MOL File
108-19-0.mol
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Biuret Property

Melting point:
185-190 °C (dec.)(lit.)
Boiling point:
100 °C
Density 
1.01 g/mL at 20 °C
refractive index 
1.4264 (estimate)
storage temp. 
2-8°C
form 
Liquid
color 
White
Odor
Odorless
Water Solubility 
2 g/100 mL (25 ºC)
Sensitive 
Hygroscopic
Merck 
14,1309
BRN 
1703510
Stability:
Stable. Incompatible with strong oxidizing agents, strong bases. Hygroscopic.
CAS DataBase Reference
108-19-0(CAS DataBase Reference)
NIST Chemistry Reference
Imidodicarbonic diamide(108-19-0)
EPA Substance Registry System
Imidodicarbonic diamide (108-19-0)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37-36
WGK Germany 
3
TSCA 
Yes
HS Code 
29241990
Hazardous Substances Data
108-19-0(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
15270
Product name
Biuret
Purity
98%
Packaging
25g
Price
$69
Updated
2021/03/22
Sigma-Aldrich
Product number
15270
Product name
Biuret
Purity
98%
Packaging
100g
Price
$169
Updated
2021/03/22
Sigma-Aldrich
Product number
PHR2603
Product name
Urea Related Compound A
Packaging
30MG
Price
$199
Updated
2021/03/22
TCI Chemical
Product number
B0513
Product name
Biuret (contains ca. 10% Triuret)
Purity
>98.0%(N)
Packaging
25g
Price
$42
Updated
2021/03/22
TCI Chemical
Product number
B0513
Product name
Biuret (contains ca. 10% Triuret)
Purity
>98.0%(N)
Packaging
500g
Price
$352
Updated
2021/03/22
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Biuret Chemical Properties,Usage,Production

Outline

Biuret is the resulting product in urea production process by deamination and condensation reaction when the temperature is higher than the melting point of urea (150-170 ℃). Formula is NH2CONHCONH2. Reaction is as follows NH2CONH2-(heating)-> HNCO + NH3, HNCO + NH2CONH2 → NH2CONHCONH2, crystallization of urea in the granulation process will generate biuret, this substance is toxic to plants, thus content of biuret in urea is required not exceed 1%. Top dressing with urea, the content of biuret should not exceed 0.5%.

Chemical Properties

It is long white sheet crystals. Melting point is 190 ℃ (decomposition), the relative density is 1.467 (-5/4 ℃). Crystals in water contain 4 molecules of water of crystallization, dehydrate at about 110 ℃. It is easily soluble in alcohol, very slightly soluble in ether.

Uses

1. Biuret is used in feed for ruminants, as feed additives as urea, like, but more safe than urea.
2. It is used as pharmaceutical intermediates, growth hormone, foaming agents, paints.
3. It is used for chemical analysis.

Reaction of binary biuret

Protein produces purple in alkaline copper sulfate solution, this is because the basic copper sulfate with proteins peptide bond (-NHCO-) formed sake complexes. On the structure of purple product, generally disagree, Xu Fu (Schiff) once separated following the reaction of compound (ⅰ) (purple crystal) from the most simple binary biuret reaction mixture, the chemical reaction equation related is as follows:

Someone studied with a spectrophotometric method, suggesting that the reaction of binary biuret produces a colored substance, which is mainly composed of a tripeptide and tetrapeptide, complexes produced by ligand of copper and tripeptide was purple, complexes produced by ligand of copper with tetrapeptide was red.
This reaction is not very sensitive, because its peptide bond with another substance that has other groups conduct the biuret reaction. Some substances without the peptide bonds (e.g., histidine) may also conduct this reaction, so its work on the application is limited.

Production method

Mix urea, water with disodium hydrogen phosphate, dissolve by heating. It was heated to 150-160 ℃, heat preservation for 2h. The reaction was completed, the reactants were poured into water and allowed to stand overnight, crystals filtered off were crude, and recrystallize with dilute ammonia to give the finished product of biuret. In the production of urea, intermediate urine is as raw material, by high temperature thermal condensation, separation, and drying, the production is obtained.

Chemical Properties

white powder

Uses

Analytical reagent, especially for proteins.

Definition

ChEBI: A member of the class of condensed ureas that is the compound formed by the condensation of two molecules of urea; the parent compound of the biuret group of compounds. Used as a non-protein nitrogen source in ruminant feed.

Definition

A colorless crystalline organic compound made by heating UREA (carbamide). It is used in a chemical test for PROTEINS.

Agricultural Uses

Biuret is a compound formed from urea when the temperature during the manufacture of urea goes above 140 to 170°C. A biuret concentration of more than 2% in urea is harmful to plants as it affects the metabolism of proteins.

Purification Methods

Crystallise biuret from EtOH. [Beilstein 3 IV 141.]

Biuret Preparation Products And Raw materials

Raw materials

Preparation Products

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Biuret Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-3668-0489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28446
Advantage
80
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96501
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40265
Advantage
62
future industrial shanghai co., ltd
Tel
400-0066-400;021-60496031
Fax
021-55660885
Email
sales@jonln.com;sales@jonln.com
Country
China
ProdList
2000
Advantage
65
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30160
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
kennyrong@hwrkchemical.com
Country
China
ProdList
17296
Advantage
55
Energy Chemical
Tel
021-58432009-
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44043
Advantage
61
Adamas Reagent, Ltd.
Tel
400-600-9262
Email
bxy@titansci.com
Country
China
ProdList
13915
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202- ;021-54308259-
Fax
+86-21-64545202
Email
info@hanhonggroup.com;info@hanhonggroup.com
Country
China
ProdList
43255
Advantage
64
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View Lastest Price from Biuret manufacturers

career henan chemical co
Product
Biuret 108-19-0
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
98%
Supply Ability
1kg,2kg,100kg
Release date
2019-07-09

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