(S)-1-Boc-2-(Hydroxymethyl)piperazine
Uses- Product Name
- (S)-1-Boc-2-(Hydroxymethyl)piperazine
- CAS No.
- 1030377-21-9
- Chemical Name
- (S)-1-Boc-2-(Hydroxymethyl)piperazine
- Synonyms
- (S)-1-Boc-2-(hyroxyMethyl)piperazine;(S)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE;(S)-N1-BOC-2-Hydroxymethyl-piperazine;(2S)-2-(Hydroxymethyl)piperazine, N1-BOC protected;(S)-tert-butyl 2-(hydroxyMethyl)piperazin-1-carboxylate;(S)-tert-butyl 2-(hydroxyMethyl)piperazine-1-carboxylate;tert-butyl (S)-2-(hydroxymethyl)piperazine-1-carboxylate;tert-butyl (2S)-2-(hydroxymethyl)piperazine-1-carboxylate;1,1-Dimethylethyl (2S)-2-(hydroxymethyl)-1-piperazinecarboxylate;(S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
- CBNumber
- CB9233339
- Molecular Formula
- C10H20N2O3
- Formula Weight
- 216.28
- MOL File
- Mol file
(S)-1-Boc-2-(Hydroxymethyl)piperazine Property
- Boiling point:
- 324℃
- Density
- 1.085
- Flash point:
- 150℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 14.97±0.10(Predicted)
Safety
- HS Code
- 2933599590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B600445
- Product name
- (S)-1-Boc-2-hydroxymethyl-piperazine
- Packaging
- 100mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- AS3135
- Product name
- (S)-1-Boc-2-(Hydroxymethyl)piperazine
- Purity
- 95+% ee
- Packaging
- 250mg
- Price
- $86
- Updated
- 2021/12/16
- Product number
- CS-D0657
- Product name
- (S)-1-Boc-2-Hydroxymethyl-piperazine
- Purity
- >97.0%
- Packaging
- 1g
- Price
- $94
- Updated
- 2021/12/16
- Product number
- X8638
- Product name
- (S)-1-Boc-(2-Hydroxymethyl)piperazine
- Packaging
- 100mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- 070014
- Product name
- (S)-1-Boc-2-(Hydroxymethyl)piperazine
- Purity
- 96+%
- Packaging
- 1g
- Price
- $165
- Updated
- 2021/12/16
(S)-1-Boc-2-(Hydroxymethyl)piperazine Chemical Properties,Usage,Production
Uses
(S)-1-N-Boc-2-hydroxymethyl piperazine is a heterocyclic compound and can be used as an intermediate in pharmaceutical synthesis.
Uses
(S)-1-Boc-2-hydroxymethyl-piperazine is a heterocyclic building block used in synthetic chemistry.
Reactions
(S)-1-Boc-2-(Hydroxymethyl)piperazine reacts with 1,2-difluoro-4-nitrobenzene to synthesize tert-butyl (S)-4-(2-fluoro-4-nitrophenyl)-2-(hydroxymethyl)piperazine-1-carboxylate. This compound serves as a crucial intermediate in the preparation of the Wee-1 kinase activity inhibitor.
Synthesis
To a solution of (S)-4-benzyl 1-tert-butyl 2-(hydroxymethyl)piperazine-1,4-dicarboxylate (1.5 g, 4.28 mmol) in MeOH (20 mL), 10 % Pd/C (150 mg) was added. The mixture was stirred at room temperature for 3 hours under H2. Afterwards, the solid was removed by filtration and the filtrate was concentrated to yield (S)-1-Boc-2-(Hydroxymethyl)piperazine (850 mg, 3.93 mmol, 91.82 percent) as a white solid.
(S)-1-Boc-2-(Hydroxymethyl)piperazine Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-1-Boc-2-(Hydroxymethyl)piperazine Suppliers
- Tel
- (+1)-858-699-3322
- Fax
- (+1)-858-876-1948
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- Country
- United States
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- 8485655694
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- United States
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- +1-833-552-7181
- sales@aladdinsci.com
- Country
- United States
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View Lastest Price from (S)-1-Boc-2-(Hydroxymethyl)piperazine manufacturers
- Product
- (S)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER 1030377-21-9
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-08