(R)-1-N-Boc-2-(hydroxymethyl)piperazine

Product Name: (R)-1-N-Boc-2-(hydroxymethyl)piperazine
CAS No.: 169448-87-7
Chemical Name: (R)-1-N-Boc-2-(hydroxymethyl)piperazine
Synonyms: Nicotinamide Impurity 202;(R)-1-Boc-2-Hydroxymethyl-piperazine;(R)-1-Boc-2-(hyroxyMethyl)piperazine;(R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl;(S)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate;tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
CBNumber: CB8948025
Molecular Formula: C10H20N2O3
Formula Weight: 216.28
MOL File: 169448-87-7.mol

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(R)-1-N-Boc-2-(hydroxymethyl)piperazine Property

Boiling point:: 324.0±17.0 °C(Predicted)
Density: 1.085±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 14.97±0.10(Predicted)

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-D0658
Product name: (R)-1-Boc-2-Hydroxymethyl-piperazine
Purity: ≥97.0%
Packaging: 250mg
Price: $50
Updated: 2021/12/16

ChemScene

Product number: CS-D0658
Product name: (R)-1-Boc-2-Hydroxymethyl-piperazine
Purity: ≥97.0%
Packaging: 1g
Price: $87
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140933
Product name: (R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate
Packaging: 250mg
Price: $100
Updated: 2021/12/16

Activate Scientific

Product number: AS3136
Product name: (R)-1-Boc-2-(Hydroxymethyl)piperazine
Purity: 97+% ee
Packaging: 1g
Price: $146
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB140933
Product name: (R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate
Packaging: 500mg
Price: $160
Updated: 2021/12/16

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(R)-1-N-Boc-2-(hydroxymethyl)piperazine Chemical Properties,Usage,Production

Uses

(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate is used in preparation of novel substituted quinoline-8-carbonitrile derivatives with androgen receptor degradation activity and uses thereof.

Synthesis

Lithium aluminum hydride (1M in THF, 26 ml) was added to a solution of L-TERT- butyl 2-methyl (2R)-piperazine-1, 2-dicarboxylate (2. 55 g) in THF (70 ml) at-40°C, and then the reaction was warmed to room temperature. After stirring for 1 h, this reaction system was cooled to 0°C and quenched by sequential addition of water (1 ml), sodium hydroxide (2N, 1 ml), and then water (2 ml). The resulting slurry was filtered and concentrated in vacuo to give (R)-1-N-Boc-2-(hydroxymethyl)piperazine.

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-1-N-Boc-2-(hydroxymethyl)piperazine Suppliers

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View Lastest Price from (R)-1-N-Boc-2-(hydroxymethyl)piperazine manufacturers

Career Henan Chemical Co

Product: (R)-1-N-Boc-2-(hydroxymethyl)piperazine 169448-87-7
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2019-12-26

169448-87-7, (R)-1-N-Boc-2-(hydroxymethyl)piperazineRelated Search:

3-(tert-Butoxycarbonylamino)cyclobutanecarboxylic acid 1-N-Boc-3-Azetidinecarboxylic acid (S)-4-Boc-Piperazine-3-carboxylic acid 1-Boc-3-(Aminomethyl)azetidine 1-Boc-3-(Amino)azetidine tert-butyl (R)-2-(2-bromophenyl)-1,4-oxazepane-4-carboxylate (R)-1-N-BOC-2-HYDROXYMETHYLPIPERIDINE tert-butyl (R)-2-(4-bromophenyl)-1,4-oxazepane-4-carboxylate tert-butyl (R)-2-((methylamino)methyl)morpholine-4-carboxylate tert-butyl (R)-2-(4-cyanophenyl)-1,4-oxazepane-4-carboxylate 1-N-BOC-2-N'-METHYL-AMINO PIPERIDINE tert-butyl (R)-2-(aminomethyl)-4,4-dimethylpyrrolidine-1-carboxylate tert-butyl (R)-2-(aminomethyl)-4,4-difluoropiperidine-1-carboxylate tert-butyl (R)-2-(aminomethyl)-5-bromoindoline-1-carboxylate (S)-1-Boc-2-Hydroxymethyl-piperazine (R)-1-BOC-3-(Hydroxymethyl)piperazine (R)-N-1-BOC-N-4-CBZ-2-PIPERAZINE CARBOXYLIC ACID (R)-N-Boc-piperazine-2-carboxylic acid methyl ester

(R)-1-Boc-2-Hydroxymethyl-piperazine

1-Piperazinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2R)-

tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate

(R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl

2-Methyl-2-propanyl(2R)-2-(hydroxymethyl)-1-piperazinecarboxylate

(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate

(R)-1-Boc-2-Hydroxymethyl-piperazine ,98%

(S)-1-Boc-2-Hydroxymethyl-piperazine ,98%

tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate

(R)-1-Boc-2-(hyroxyMethyl)piperazine

(R)-1-N-Boc-2-(hydroxymethyl)piperazine###(R)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(2R)-2-(hydroxymethyl)-1-Piperazinecarboxylic acid tert-butyl ester

tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate

Nicotinamide Impurity 202

169448-87-7

16944-87-7

169448-87-8

Piperaizine