ChemicalBook > CAS DataBase List > (R)-1-N-Boc-2-(hydroxymethyl)piperazine

(R)-1-N-Boc-2-(hydroxymethyl)piperazine

Product Name
(R)-1-N-Boc-2-(hydroxymethyl)piperazine
CAS No.
169448-87-7
Chemical Name
(R)-1-N-Boc-2-(hydroxymethyl)piperazine
Synonyms
Nicotinamide Impurity 202;(R)-1-Boc-2-Hydroxymethyl-piperazine;(R)-1-Boc-2-(hyroxyMethyl)piperazine;(R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl;(S)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate;tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
CBNumber
CB8948025
Molecular Formula
C10H20N2O3
Formula Weight
216.28
MOL File
169448-87-7.mol
More
Less

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Property

Boiling point:
324.0±17.0 °C(Predicted)
Density 
1.085±0.06 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
14.97±0.10(Predicted)
More
Less

Safety

HS Code 
2933599590
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

ChemScene
Product number
CS-D0658
Product name
(R)-1-Boc-2-Hydroxymethyl-piperazine
Purity
≥97.0%
Packaging
250mg
Price
$50
Updated
2021/12/16
ChemScene
Product number
CS-D0658
Product name
(R)-1-Boc-2-Hydroxymethyl-piperazine
Purity
≥97.0%
Packaging
1g
Price
$87
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140933
Product name
(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate
Packaging
250mg
Price
$100
Updated
2021/12/16
Activate Scientific
Product number
AS3136
Product name
(R)-1-Boc-2-(Hydroxymethyl)piperazine
Purity
97+% ee
Packaging
1g
Price
$146
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB140933
Product name
(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate
Packaging
500mg
Price
$160
Updated
2021/12/16
More
Less

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Chemical Properties,Usage,Production

Uses

(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate is used in preparation of novel substituted quinoline-8-carbonitrile derivatives with androgen receptor degradation activity and uses thereof.

Synthesis

Lithium aluminum hydride (1M in THF, 26 ml) was added to a solution of L-TERT- butyl 2-methyl (2R)-piperazine-1, 2-dicarboxylate (2. 55 g) in THF (70 ml) at-40°C, and then the reaction was warmed to room temperature. After stirring for 1 h, this reaction system was cooled to 0°C and quenched by sequential addition of water (1 ml), sodium hydroxide (2N, 1 ml), and then water (2 ml). The resulting slurry was filtered and concentrated in vacuo to give (R)-1-N-Boc-2-(hydroxymethyl)piperazine.

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(R)-1-N-Boc-2-(hydroxymethyl)piperazine Suppliers

China 103 Europe 1 Germany 2 India 1 United Kingdom 3 United States 15 Global 125
Pharmavoyager
Tel
15351203386
Email
2592141051@qq.com
Country
China
ProdList
93
Advantage
55
ForeChem (Nantong) Technology Co.,Ltd.
Tel
513-85982855 18921614129
Fax
051385915507
Email
sales@xianxingpharm.com
Country
China
ProdList
1819
Advantage
61
Kangyue Huilan Pharmaceutical Technology Co., Ltd
Tel
028-81092800 17323275954
Email
2567869566@qq.com
Country
China
ProdList
466
Advantage
58
Nanjing Asfam Pharmaceutical Technology Co., Ltd.
Tel
025-58867862 18751812725
Fax
02558867862
Email
sales@ace-pharm.com
Country
China
ProdList
1997
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
94838
Advantage
76
Sichuan Guanghan Bio-Tech Co., Ltd
Tel
+86-28-86127071
Fax
+86-28-86127072
Email
info@sino-produce.com
Country
China
ProdList
411
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
zhangsn@titansci.com
Country
China
ProdList
14113
Advantage
59
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Shanghai Boc Chemical Co.,Ltd
Tel
021-34975603-808 18721111801
Fax
+86-21-34975602-805
Email
sales@bocpharma.com
Country
China
ProdList
995
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
18087
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-021-64543801 13764082696
Email
2355241799@qq.com
Country
China
ProdList
42982
Advantage
64
China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6943
Advantage
65
Shanghai Sphchem Co., Ltd.
Tel
21-21-56491756 13512199871
Fax
021-5649-1756
Email
sales@panhongchem.com
Country
China
ProdList
4000
Advantage
55
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8888
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
18017383231 18017383231
Fax
qq：2817624287
Email
lyh_antaeus@163.com
Country
China
ProdList
9352
Advantage
55
Acesys Pharmatech
Tel
18860950986
Email
tangmanman@zenjipharma.com
Country
China
ProdList
1735
Advantage
55
EnliPharma Technology Co., Ltd
Tel
0551-66399836 18955197623
Email
sales@enlipharma.com
Country
China
ProdList
1874
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9907
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Porse Fine Chemical Co.,LTD
Tel
20-66003216 18666003216
Fax
+86-20-28069063
Email
info@porsefinechemical.com
Country
China
ProdList
2134
Advantage
62
Chengdu Firster Pharmaceutical Co., Ltd.
Tel
028-87078428 028-87074958
Fax
8772-8116
Email
chengzhenyong@cdfirster.com
Country
China
ProdList
1989
Advantage
60
NINGBO INNO PHARMCHEM CO.,LTD.
Tel
86-574-27787657
Fax
86-574-27912196
Email
info@dearchem.com
Country
China
ProdList
4619
Advantage
58
Shanghai HuanChuan Industry Co.,Ltd.
Tel
021-61478794
Fax
021-61478794
Email
sales@hcshhai.com
Country
China
ProdList
9798
Advantage
50
Nanjing Derno Pharmaceutical Technology Co., Ltd.
Tel
025-86957866 13952093866
Fax
025-68661287
Email
sales@dernopharm.com
Country
China
ProdList
924
Advantage
58
Cool Pharm, Ltd
Tel
021-60455363 18019463053
Fax
50966098
Email
sales@coolpharm.com
Country
China
ProdList
12357
Advantage
58
Lanzhou HuaHao Pharmaceutical Co., Ltd.
Tel
18189674620
Email
761137152@qq.com
Country
China
ProdList
490
Advantage
55
SanoChem (Chengdu) Tech. Co., Ltd.
Tel
28-87999436 02887999436
Fax
QQ:2746983436
Email
sales@sano-chem.com
Country
China
ProdList
3929
Advantage
55
NovoChemy Ltd.
Tel
86-(0)21-31261262 373522135
Fax
86-(0)21-33250524
Email
sales@novochemy.com
Country
China
ProdList
6508
Advantage
58
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9254
Advantage
55
TaiChem Taizhou Limited
Tel
052386810091
Email
zcwy9518@yeah.net
Country
China
ProdList
3871
Advantage
58
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9934
Advantage
55
ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
Email
tcy@tcypharm.com
Country
China
ProdList
5489
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131980
Advantage
58
Hubei Yangxin Medical Technology Co., Ltd.
Tel
15374522761
Fax
QQ:2853117752
Email
3003392093@qq.com
Country
China
ProdList
8012
Advantage
55
Wuhan EEChem Technologies Co., Ltd
Tel
0711-3617768 13308685235
Fax
0711-3616558
Email
lihongcai4360@sina.com
Country
China
ProdList
1370
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28821
Advantage
58
Hangzhou Molcore Biopharmatech Co.,Ltd
Tel
400-711-5280 86-571-81025280
Fax
86-571-85806285
Email
sales@molcore.com
Country
China
ProdList
9974
Advantage
58
LinkChem Co.,Ltd.
Tel
021-021-58950110 13124863828
Fax
021-20922272
Email
sales@linkchem.cn
Country
China
ProdList
3000
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
(5)02557626880
Email
cb6@aikonchem.com
Country
China
ProdList
15495
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 18521078705
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
19986
Advantage
58
Shanghai He Huan Chemical Co., Ltd.
Tel
021-60345187 13917602471
Fax
021-60345187
Email
lzz841106@aliyun.com
Country
China
ProdList
9907
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
24971
Advantage
58
Suzhou Devi Pharma Technology Co., Ltd.
Tel
0512-66565816 18651107528
Fax
0512-66565816
Country
China
ProdList
1040
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
400-400-400-9004166 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52712
Advantage
58
Shenzhen Polymeri Biochemical Technology Co., Ltd.
Tel
+86-400-002-6226 13028896684
Email
sales@rrkchem.com
Country
China
ProdList
55954
Advantage
58
Shanghai Akasaka Biotechnology Co., Ltd.
Tel
15121162054
Country
CHINA
ProdList
635
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
CHINA
ProdList
52861
Advantage
58
Hefei Hirisun Pharmatech Co., Ltd
Tel
+8615056975894
Fax
86-0551-62678551
Email
shawn@hirisunpharm.com
Country
CHINA
ProdList
9923
Advantage
58
Blocksynth Pharmaceutical Technology Co.,Ltd
Tel
0086-19817745290; +8619817745290
Email
bd@blocksynth.com
Country
China
ProdList
5658
Advantage
58
More
Less

View Lastest Price from (R)-1-N-Boc-2-(hydroxymethyl)piperazine manufacturers

Career Henan Chemical Co
Product
(R)-1-N-Boc-2-(hydroxymethyl)piperazine 169448-87-7
Price
US $6.60/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2019-12-26

169448-87-7, (R)-1-N-Boc-2-(hydroxymethyl)piperazineRelated Search:

3-(tert-Butoxycarbonylamino)cyclobutanecarboxylic acid 1-N-Boc-3-Azetidinecarboxylic acid (S)-4-Boc-Piperazine-3-carboxylic acid 1-Boc-3-(Aminomethyl)azetidine 1-Boc-3-(Amino)azetidine tert-butyl (R)-2-(2-bromophenyl)-1,4-oxazepane-4-carboxylate (R)-1-N-BOC-2-HYDROXYMETHYLPIPERIDINE tert-butyl (R)-2-(4-bromophenyl)-1,4-oxazepane-4-carboxylate tert-butyl (R)-2-((methylamino)methyl)morpholine-4-carboxylate tert-butyl (R)-2-(4-cyanophenyl)-1,4-oxazepane-4-carboxylate 1-N-BOC-2-N'-METHYL-AMINO PIPERIDINE tert-butyl (R)-2-(aminomethyl)-4,4-dimethylpyrrolidine-1-carboxylate tert-butyl (R)-2-(aminomethyl)-4,4-difluoropiperidine-1-carboxylate tert-butyl (R)-2-(aminomethyl)-5-bromoindoline-1-carboxylate (S)-1-Boc-2-Hydroxymethyl-piperazine (R)-1-BOC-3-(Hydroxymethyl)piperazine (R)-N-1-BOC-N-4-CBZ-2-PIPERAZINE CARBOXYLIC ACID (R)-N-Boc-piperazine-2-carboxylic acid methyl ester

  • (R)-1-Boc-2-Hydroxymethyl-piperazine
  • 1-Piperazinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2R)-
  • tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate
  • (R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl
  • 2-Methyl-2-propanyl(2R)-2-(hydroxymethyl)-1-piperazinecarboxylate
  • (R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate
  • (R)-1-Boc-2-Hydroxymethyl-piperazine ,98%
  • (S)-1-Boc-2-Hydroxymethyl-piperazine ,98%
  • tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
  • (R)-1-Boc-2-(hyroxyMethyl)piperazine
  • (R)-1-N-Boc-2-(hydroxymethyl)piperazine###(R)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
  • (2R)-2-(hydroxymethyl)-1-Piperazinecarboxylic acid tert-butyl ester
  • tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate
  • Nicotinamide Impurity 202
  • 169448-87-7
  • 16944-87-7
  • 169448-87-8
  • Piperaizine