5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one

Product Name: 5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
CAS No.: 18110-86-6
Chemical Name: 5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one
Synonyms: Nigakinone;1-carbomehoxy-carboline;Nigakinone, 10 mM in DMSO;5-Hydroxy-4-methoxycanthin-6-one;4-Methoxy-5-hydroxycanthin-6-one;5-HYDROXY-4-METHOXY-6H-INDOLO[3,2,1-IJ][1,5]NAPHTHYRIDIN-6-ONE;5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one;6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 5-hydroxy-4-methoxy-
CBNumber: CB92418679
Molecular Formula: C15H10N2O3
Formula Weight: 266.25
MOL File: 18110-86-6.mol

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5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one Property

Melting point:: 224-225 °C
Boiling point:: 442.7±45.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
solubility: Methanol: Soluble
pka: 2.42±0.20(Predicted)
form: Solid
color: Light yellow to yellow
InChI: InChI=1S/C15H10N2O3/c1-20-14-11-12-9(6-7-16-11)8-4-2-3-5-10(8)17(12)15(19)13(14)18/h2-7,18H,1H3
InChIKey: PGFKZUOYIFDMQJ-UHFFFAOYSA-N
SMILES: N1C2=C3N(C4=C(C3=CC=1)C=CC=C4)C(=O)C(O)=C2OC

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0018679
Product name: Nigakinone
Purity: >98.0%
Packaging: 5mg
Price: $550
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb572954
Product name: Nigakinone
Purity: >98%
Packaging: 100mg
Price: $1431.4
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb572954
Product name: Nigakinone
Purity: >98%
Packaging: 250mg
Price: $2839
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb572954
Product name: Nigakinone
Purity: >98%
Packaging: 1g
Price: $5654.2
Updated: 2021/12/16

Arctom

Product number: CFN99846
Product name: 5-Hydroxy-4-methoxycanthin-6-one
Packaging: 5mg
Price: $288
Updated: 2021/12/16

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5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one Chemical Properties,Usage,Production

Chemical Properties

Yellow crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from bitter wood.

Uses

5-Hydroxy-4-methoxycanthin-7-one has the antibacterial effect.

Definition

ChEBI: Nigakinone is a member of beta-carbolines.

Biological Activity

Nigakinone is one of the most abundant alkaloids in bitter wood with important pharmacological activity.

References

[1] HUAYING FAN . In vitro and in vivo anti-inflammatory effects of 4-methoxy-5- hydroxycanthin-6-one, a natural alkaloid from Picrasma quassioides[J]. Phytomedicine, 2013, 20 3: Pages 319-323. DOI: 10.1016/j.phymed.2012.11.016
[2] FANGLE LIU. Nigakinone alleviates DSS-induced experimental colitis via regulating bile acid profile and FXR/NLRP3 signaling pathways.[J]. Phytotherapy Research, 2023, 37 1: 15-34. DOI: 10.1002/ptr.7588

5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one Preparation Products And Raw materials

Raw materials

Preparation Products

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5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one Suppliers

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View Lastest Price from 5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one manufacturers

Career Henan Chemical Co

Product: 5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one 18110-86-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-03

18110-86-6, 5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-oneRelated Search:

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5-Hydroxy-4-methoxy-6H-indolo[3,2,1-de][1,5]naphthyridin-6-one

Nigakinone

5-Hydroxy-4-methoxycanthin-6-one

5-HYDROXY-4-METHOXY-6H-INDOLO[3,2,1-IJ][1,5]NAPHTHYRIDIN-6-ONE

1-carbomehoxy-carboline

6H-Indolo[3,2,1-de][1,5]naphthyridin-6-one, 5-hydroxy-4-methoxy-

4-Methoxy-5-hydroxycanthin-6-one

Nigakinone, 10 mM in DMSO

18110-86-6

118110-86-6