ChemicalBook > CAS DataBase List > 2-AMINO-5-IODOPYRAZINE

2-AMINO-5-IODOPYRAZINE

Product Name
2-AMINO-5-IODOPYRAZINE
CAS No.
886860-50-0
Chemical Name
2-AMINO-5-IODOPYRAZINE
Synonyms
5-iodo-2-Pyrazinamine;5-iodopyrazin-2-aMine;2-AMINO-5-IODOPYRAZINE;2-Pyrazinamine, 5-iodo-
CBNumber
CB92452790
Molecular Formula
C4H4IN3
Formula Weight
221
MOL File
886860-50-0.mol
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2-AMINO-5-IODOPYRAZINE Property

Melting point:
122-123°
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
Appearance
Light yellow to brown Solid
InChI
InChI=1S/C4H4IN3/c5-3-1-8-4(6)2-7-3/h1-2H,(H2,6,8)
InChIKey
VVTVALQVXWRFAM-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(I)N=C1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
A576733
Product name
2-Amino-5-iodopyrazine
Packaging
10mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA32963
Product name
2-Amino-5-iodopyrazine
Packaging
100mg
Price
$69
Updated
2021/12/16
Matrix Scientific
Product number
072328
Product name
2-Amino-5-iodopyrazine
Purity
95+%
Packaging
1g
Price
$24
Updated
2021/12/16
AK Scientific
Product number
J94248
Product name
2-Amino-5-iodopyrazine
Packaging
1g
Price
$30
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA32963
Product name
2-Amino-5-iodopyrazine
Packaging
250mg
Price
$132.5
Updated
2021/12/16
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2-AMINO-5-IODOPYRAZINE Chemical Properties,Usage,Production

Synthesis

5049-61-6

886860-50-0

To a 1000 mL single neck round bottom flask was added 2-aminopyrazine (28.50 g, 300 mmol) and N-iodosuccinimide (134.99 g, 600 mmol) followed by methanol (340 mL). The reaction mixture was stirred at 80 °C for 10 hours. The reaction progress was monitored by thin layer chromatography (TLC) and gas chromatography (GC) to confirm the completion of the reaction. Upon completion of the reaction, the solvent was removed using a rotary evaporator to obtain the crude product. The crude product was purified by silica gel column chromatography to obtain the target compound 2-amino-5-iodopyrazine. The product was dried and the yield was calculated to be 70.50% and analyzed by high performance liquid chromatography (HPLC) with a purity of 99.58%.

References

[1] Patent: CN106674137, 2017, A. Location in patent: Paragraph 0009-0011; 0012-0014; 0015-0016
[2] Heterocycles, 2012, vol. 86, # 2, p. 1323 - 1339
[3] Patent: JP2015/54838, 2015, A. Location in patent: Paragraph 0083; 0084

2-AMINO-5-IODOPYRAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-5-IODOPYRAZINE Suppliers

China 65 India 1 United Kingdom 2 United States 10 Global 78
Carbosynth
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46

886860-50-0, 2-AMINO-5-IODOPYRAZINERelated Search:

Iodopyrazine 3-AMINO-6-IODOPYRAZINE-2-CARBOXYLIC ACID 2-AMINO-5-IODO-3-METHYLPYRAZINE 2,3-DIIODO-5-PIPERAZIN-1-YLPYRAZINE 3-AMINO-6-IODOPYRAZINE-2-CARBOXYLIC ACID METHYL ESTER 6-Iodoamiloride,hydrochloridedihydrate 2-AMINO-5-IODOPYRAZINE

  • 2-AMINO-5-IODOPYRAZINE
  • 5-iodopyrazin-2-aMine
  • 5-iodo-2-Pyrazinamine
  • 2-Pyrazinamine, 5-iodo-
  • 886860-50-0