5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE

Uses

Product Name: 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE
CAS No.: 50727-06-5
Chemical Name: 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE
Synonyms: 4-HydroxyphthaliMide;5-hydroxyisoindole-1,3-dione;5-Hydroxyisoindoline-1,3-dione;5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE;1H-Isoindole-1,3(2H)-dione, 5-hydroxy-
CBNumber: CB92455908
Molecular Formula: C8H5NO3
Formula Weight: 163.13
MOL File: 50727-06-5.mol

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5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Property

Melting point:: 290 °C(Solv: ethanol (64-17-5))
Density: 1.539±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 6.98±0.20(Predicted)
Appearance: Off-white to brown Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

TRC

Product number: H900065
Product name: 5-Hydroxyisoindoline-1,3-dione
Packaging: 1g
Price: $350
Updated: 2021/12/16

ChemScene

Product number: CS-W006520
Product name: 5-Hydroxyisoindoline-1,3-dione
Purity: 99.97%
Packaging: 5g
Price: $489
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0390777
Product name: 5-HYDROXYISOINDOLINE-1,3-DIONE
Purity: 95.00%
Packaging: 5MG
Price: $498.59
Updated: 2021/12/16

ChemScene

Product number: CS-W006520
Product name: 5-Hydroxyisoindoline-1,3-dione
Purity: 99.97%
Packaging: 10g
Price: $790
Updated: 2021/12/16

AK Scientific

Product number: 8399CR
Product name: 5-Hydroxyisoindoline-1,3-dione
Packaging: 5g
Price: $799
Updated: 2021/12/16

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5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Chemical Properties,Usage,Production

Uses

5-Hydroxyisoindoline-1,3-dione is a useful research chemical.

Synthesis

610-35-5

50727-06-5

Step 1. Synthesis of 5-hydroxyisoindoline-1,3-dione To a concentrated hydrochloric acid mixture of ammonium carbonate (5.28 g, 54.9 mmol), 4-hydroxyphthalic acid (5.0 g, 27.45 mmol) dissolved in acetic acid (25 mL) was slowly added. The reaction mixture was heated at 120 °C for 45 min, then warmed up to 160 °C for further heating for 2 hours. Upon completion of the reaction, the mixture was concentrated to about 15 mL at 160 °C and then cooled to room temperature. The pH was adjusted to 10 with 1N NaOH solution and subsequently the mixture was cooled to 0 °C and slowly acidified to pH 5 with 1N HCl solution.The resulting precipitate was collected by filtration and dried under reduced pressure to afford 5-hydroxyisoindoline-1,3-dione as a pale yellow powder (3.24 g, 72% yield). The product was characterized by 1H NMR (DMSO-d6): δ 7.00-7.03 (m, 2H), 7.56 (d, J = 9.3 Hz, 1H).

References

[1] Patent: US2003/144278, 2003, A1
[2] Patent: US2003/181442, 2003, A1
[3] Patent: US2001/11135, 2001, A1
[4] Patent: US2002/165394, 2002, A1
[5] Patent: US2003/207872, 2003, A1. Location in patent: Page/Page column 9

5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Suppliers

China 34 India 1 United States 3 Global 38

Adamas Reagent, Ltd.

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View Lastest Price from 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE manufacturers

YiZheng HaiFan Chemical CO., LTD.

Product: 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE 50727-06-5
Price: US $0.00/kgs/paper drum
Min. Order: 25kgs/paper drum
Purity: 98%
Supply Ability: 10 tons
Release date: 2025-11-17

50727-06-5, 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONERelated Search:

1-(2,6-Dichlorophenyl)-2-hydroindole 4-Hydroxyindole 6-Hydroxyindole 3-Acetyl-1-propanol 5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL) INDOLIN-2-ONE 2,2-BIS[4-(N-METHYLPHTHALIMIDO-4-OXY)PHENYL]PROPANE DPS-CL 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE AKOS 237-117 AKOS 200-57 AKOS 227-93 AKOS 245-26 AKOS 213-160 AKOS 213-64 AKOS 212-82 SALOR-INT L170852-1EA 5-(4-AMINOPHENOXY)-2-(4-METHYLPHENYL)-1H-ISOINDOLE-1,3(2H)-DIONE AKOS 220-68

5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE

4-HydroxyphthaliMide

5-Hydroxyisoindoline-1,3-dione

1H-Isoindole-1,3(2H)-dione, 5-hydroxy-

5-hydroxyisoindole-1,3-dione

50727-06-5