5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE
Uses- Product Name
- 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE
- CAS No.
- 50727-06-5
- Chemical Name
- 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE
- Synonyms
- 4-HydroxyphthaliMide;5-hydroxyisoindole-1,3-dione;5-Hydroxyisoindoline-1,3-dione;5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE;1H-Isoindole-1,3(2H)-dione, 5-hydroxy-
- CBNumber
- CB92455908
- Molecular Formula
- C8H5NO3
- Formula Weight
- 163.13
- MOL File
- 50727-06-5.mol
5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Property
- Melting point:
- 290 °C(Solv: ethanol (64-17-5))
- Density
- 1.539±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 6.98±0.20(Predicted)
- Appearance
- Off-white to brown Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- H900065
- Product name
- 5-Hydroxyisoindoline-1,3-dione
- Packaging
- 1g
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-W006520
- Product name
- 5-Hydroxyisoindoline-1,3-dione
- Purity
- 99.97%
- Packaging
- 100mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- CS-W006520
- Product name
- 5-Hydroxyisoindoline-1,3-dione
- Purity
- 99.97%
- Packaging
- 250mg
- Price
- $64
- Updated
- 2021/12/16
- Product number
- OR941420
- Product name
- 5-Hydroxyisoindoline-1,3-dione
- Purity
- 95%
- Packaging
- 250mg
- Price
- $130
- Updated
- 2021/12/16
- Product number
- CS-W006520
- Product name
- 5-Hydroxyisoindoline-1,3-dione
- Purity
- 99.97%
- Packaging
- 1g
- Price
- $160
- Updated
- 2021/12/16
5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Chemical Properties,Usage,Production
Uses
5-Hydroxyisoindoline-1,3-dione is a useful research chemical.
Synthesis
610-35-5
50727-06-5
Step 1. Synthesis of 5-hydroxyisoindoline-1,3-dione To a concentrated hydrochloric acid mixture of ammonium carbonate (5.28 g, 54.9 mmol), 4-hydroxyphthalic acid (5.0 g, 27.45 mmol) dissolved in acetic acid (25 mL) was slowly added. The reaction mixture was heated at 120 °C for 45 min, then warmed up to 160 °C for further heating for 2 hours. Upon completion of the reaction, the mixture was concentrated to about 15 mL at 160 °C and then cooled to room temperature. The pH was adjusted to 10 with 1N NaOH solution and subsequently the mixture was cooled to 0 °C and slowly acidified to pH 5 with 1N HCl solution.The resulting precipitate was collected by filtration and dried under reduced pressure to afford 5-hydroxyisoindoline-1,3-dione as a pale yellow powder (3.24 g, 72% yield). The product was characterized by 1H NMR (DMSO-d6): δ 7.00-7.03 (m, 2H), 7.56 (d, J = 9.3 Hz, 1H).
References
[1] Patent: US2003/144278, 2003, A1
[2] Patent: US2003/181442, 2003, A1
[3] Patent: US2001/11135, 2001, A1
[4] Patent: US2002/165394, 2002, A1
[5] Patent: US2003/207872, 2003, A1. Location in patent: Page/Page column 9
5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Preparation Products And Raw materials
Raw materials
Preparation Products
5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE manufacturers
- Product
- 5-HYDROXY-1H-ISOINDOLE-1,3(2H)-DIONE 50727-06-5
- Price
- US $0.00/kgs/paper drum
- Min. Order
- 25kgs/paper drum
- Purity
- 98%
- Supply Ability
- 10 tons
- Release date
- 2025-11-17