ChemicalBook > CAS DataBase List > ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE

ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE

Product Name
ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE
CAS No.
58610-65-4
Chemical Name
ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE
Synonyms
Ethyl 6′-cyano-2′,3′-dihydro-5′-oxospiro[1,3-dioxolane-2,1′(5′H)-indolizine]-7′-acetate;Ethyl 2-(6-cyano-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)acetate;6-cyano-1,1-(ethylenedioxy)-7-[(ethoxycarbonyl)methyl]-5-oxo-Δ6(8)-tetrahydroindolizine;Ethyl (6'-cyano-5'-oxo-2',3'-dihydro-5'H-spiro[1,3-dioxolane-2,1'-indolizin]-7'-yl)acetate;Ethyl 2-(6'-cyano-5'-oxo-3',5'-dihydro-2'H-spiro[[1,3]dioxolane-2,1'-indolizin]-7'-yl)acetate;ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE;Spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic acid, 6'-cyano-2',3'-dihydro-5'-oxo-, ethyl ester
CBNumber
CB92463538
Molecular Formula
C15H16N2O5
Formula Weight
304.3
MOL File
58610-65-4.mol
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ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE Property

storage temp. 
Store at 0-8 °C
solubility 
soluble in Dichloromethane, Methanol
form 
Solid
color 
Green
InChI
InChI=1S/C15H16N2O5/c1-2-20-13(18)8-10-7-12-15(21-5-6-22-15)3-4-17(12)14(19)11(10)9-16/h7H,2-6,8H2,1H3
InChIKey
FQVVPISPHQOPFC-UHFFFAOYSA-N
SMILES
O1CCOC21C1N(C(=O)C(C#N)=C(CC(OCC)=O)C=1)CC2
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
C979190
Product name
6''-Cyano-2'',3''-dihydro-5''-oxo-spiro[1,3-dioxolane-2,1''(5''H)-indolizine]-7''-aceticAcidEthylEster
Packaging
5mg
Price
$165
Updated
2021/12/16
TRC
Product number
C979190
Product name
6''-Cyano-2'',3''-dihydro-5''-oxo-spiro[1,3-dioxolane-2,1''(5''H)-indolizine]-7''-aceticAcidEthylEster
Packaging
50mg
Price
$1320
Updated
2021/12/16
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ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE Chemical Properties,Usage,Production

Uses

Used in the preparation of Camptothecin derivatives, for their therapeutic use as antitumor agents.

ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE Suppliers

MoleArk Biotech
Tel
18815611055
Email
805482182@qq.com
Country
China
ProdList
199
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58
QINGDAO CARELONGPHARMATECH CO.,LTD
Tel
0532-0532-88191853 13061484198
Fax
+86-532-88191853
Email
sales@carelongchem.com
Country
China
ProdList
437
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Tianjin Being Technology Co., Ltd.
Tel
18622939839
Fax
QQ:343281693
Email
tjby921@163.com
Country
China
ProdList
884
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55
Nanjing XiLang Chemical Products Co., Ltd.
Tel
18936048580
Email
chemxilang@163.com
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China
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3909
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ChengDu TongChuangYuan Pharmaceutical Co.Ltd
Tel
028-83379370 13880556291
Fax
028-87747383
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tcy@tcypharm.com
Country
China
ProdList
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Jinan Kabotang Biological Technology Co.,Ltd.
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0531-61320525 15866703830
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China
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Chengdu Zen Sunda Bio-pharmaceutical Technology Co., Ltd.
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19981275275
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sales@zsdpharm.com
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Jinan Guoding Pharmaceutical Technology Co., Ltd.
Tel
053167801621 15665775653
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053167801621
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China
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Chengdu Feibai Pharmaceutical Co., Ltd.
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028-84641798 18782128315
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Suzhou Rovathin Foreign Trade Co.,Ltd
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58610-65-4, ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATERelated Search:


  • ETHYL 2-(6'-CYANO-5'-OXO-3',5'-DIHYDRO-2'H-SPIRO[[1,3]DIOXOLANE-2,1'-INDOLIZINE]-7'-YL)ACETATE
  • Spiro[1,3-dioxolane-2,1'(5'H)-indolizine]-7'-acetic acid, 6'-cyano-2',3'-dihydro-5'-oxo-, ethyl ester
  • Ethyl 2-(6-cyano-5-oxo-2,3-dihydro-5H-spiro[indolizine-1,2'-[1,3]dioxolan]-7-yl)acetate
  • Ethyl 6′-cyano-2′,3′-dihydro-5′-oxospiro[1,3-dioxolane-2,1′(5′H)-indolizine]-7′-acetate
  • Ethyl 2-(6'-cyano-5'-oxo-3',5'-dihydro-2'H-spiro[[1,3]dioxolane-2,1'-indolizin]-7'-yl)acetate
  • 6-cyano-1,1-(ethylenedioxy)-7-[(ethoxycarbonyl)methyl]-5-oxo-Δ6(8)-tetrahydroindolizine
  • Ethyl (6'-cyano-5'-oxo-2',3'-dihydro-5'H-spiro[1,3-dioxolane-2,1'-indolizin]-7'-yl)acetate
  • 58610-65-4