ChemicalBook > CAS DataBase List > TRIPTOQUINONEB

TRIPTOQUINONEB

Product Name
TRIPTOQUINONEB
CAS No.
142937-50-6
Chemical Name
TRIPTOQUINONEB
Synonyms
Triptoquine B;TRIPTOQUINONEB;1,4,7(4bH)-Phenanthrenetrione, 5,6,8,8a,9,10-hexahydro-8-(hydroxymethyl)-4b,8-dimethyl-2-(1-methylethyl)-, (4bS,8S,8aR)-
CBNumber
CB92468205
Molecular Formula
C20H26O4
Formula Weight
330.42
MOL File
142937-50-6.mol
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TRIPTOQUINONEB Property

Boiling point:
475.4±45.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
Powder
pka
14.25±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom
Product number
CFN99474
Product name
TriptoquinoneB
Packaging
5mg
Price
$553
Updated
2021/12/16
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TRIPTOQUINONEB Chemical Properties,Usage,Production

Uses

Triptoquinone B ((+)-Triptoquinone B), a sesquiterpene alkaloid, is an interleukin-1 inhibitor. Triptoquinone B shows potent inhibitory activities against interleukin 1α and β releases for human peripheral mononuclear cells[1][2].

Definition

ChEBI: An abietane diterpenoid with formula C20H26O4, originally isolated from Tripterygium wilfordii.

target

IL Receptor

IC 50

IL-1

References

[1] Takaishi Y, et, al. Triptoquinone A and B novel interleukin-1 inhibitors from Tripterygium wilfordii var Regeli. Tetrahedron Letters. 1992 Nov; 33(47): 7177-7180.
[2] Wang XD, et, al. Terpene alkaloids from Tripterygium wilfordii. J Asian Nat Prod Res. 2005 Oct;7(5):755-9. DOI:10.1080/1028602042000325618

TRIPTOQUINONEB Preparation Products And Raw materials

Raw materials

Preparation Products

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142937-50-6, TRIPTOQUINONEBRelated Search:

alpha-Cyperone 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one alpha-Terpineol beta-Sitosterol hydroxygenkwanin MOSLOFLAVONE Artemether (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one beta-Eudesmol Hydroxyecdysone

  • TRIPTOQUINONEB
  • Triptoquine B
  • 1,4,7(4bH)-Phenanthrenetrione, 5,6,8,8a,9,10-hexahydro-8-(hydroxymethyl)-4b,8-dimethyl-2-(1-methylethyl)-, (4bS,8S,8aR)-
  • 142937-50-6