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CINANSERIN HYDROCHLORIDE

Product Name
CINANSERIN HYDROCHLORIDE
CAS No.
1166-34-3
Chemical Name
CINANSERIN HYDROCHLORIDE
Synonyms
DPTC;CINANSERIN;Cinanserine;DPTC HYDROCHLORIDE;CINANSERIN HYDROCHLORIDE;2'-(3-DIMETHYLAMINOPROPYL-THIO)-CINNAMANILIDE HYDROCHLORIDE;N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenylpropenamide;N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE;2-Propenamide, N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-;N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE HYDROCHLORIDE
CBNumber
CB9254024
Molecular Formula
C20H24N2OS
Formula Weight
340.48
MOL File
1166-34-3.mol
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CINANSERIN HYDROCHLORIDE Property

Melting point:
82-83 °C
Boiling point:
519.5±50.0 °C(Predicted)
Density 
1.13±0.1 g/cm3(Predicted)
RTECS 
UC6323000
storage temp. 
Desiccate at RT
solubility 
Chloroform (Slightly), Methanol (Slightly)
form 
Solid
pka
13.46±0.70(Predicted)
color 
White to Off-White
Water Solubility 
Soluble to 50 mM in water
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

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N-Bromosuccinimide Price

TRC
Product number
C441903
Product name
Cinanserin
Packaging
100mg
Price
$1115
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0015845
Product name
2'-(3-DIMETHYLAMINOPROPYLTHIO)CINNAMANILIDE
Purity
95.00%
Packaging
10MG
Price
$281.4
Updated
2021/12/16
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CINANSERIN HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Serotonin inhibitor.

Uses

A 5-HT antagonist

Definition

ChEBI: Cinanserin is an aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antiviral agent and an anticoronaviral agent. It is a tertiary amino compound, a secondary carboxamide, a member of cinnamamides and an aryl sulfide. It is a conjugate base of a cinanserin(1+).

Biological Activity

5-HT 2 antagonist.

in vivo

Cinanserin (5 mg/kg; i.v.) treatment significantly reduces systemic burn edema levels[1].

Animal Model:Male Wistar rats (250 g) underwent thermal injury[1]
Dosage:5 mg/kg
Administration:Intravenous injection; for 2 hours
Result:Significantly reduced systemic burn edema to shamburn levels, leukocyte-endothelial interactions are significantly reduced by administration of Cinanserin.

IC 50

5-HT2 Receptor: 41 nM (Ki); 5-HT1 Receptor: 3500 nM (Ki); SARS-CoV 3CLpro: 49.4 μM (Kd)

CINANSERIN HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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CINANSERIN HYDROCHLORIDE Suppliers

China 34 Europe 1 Germany 2 India 1 United Kingdom 2 United States 7 Global 47
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
18333
Advantage
56
EMMX Biotechnology LLC
Tel
888-539-0666
Fax
888-539-0666
Email
info@emmx.com
Country
United States
ProdList
8447
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Career Henan Chemica Co
Tel
+86-0371-86658258 +8613203830695
Fax
0371-86658258
Email
laboratory@coreychem.com
Country
China
ProdList
30229
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-29-81148696 +86-17392712697
Email
1022@dideu.com
Country
China
ProdList
3995
Advantage
58
Energy Chemical
Tel
021-58432009 400-005-6266
Fax
021-58436166
Email
marketing1@energy-chemical.com
Country
China
ProdList
44894
Advantage
58
cjbscvictory
Tel
13348960310
Email
3003867561@qq.com
Country
China
ProdList
10503
Advantage
58
Foshan Treasure Biotechnology Co., Ltd
Tel
0757-85921206 18520245316
Email
2329783215@qq.com
Country
China
ProdList
12661
Advantage
58
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View Lastest Price from CINANSERIN HYDROCHLORIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
CINANSERIN HYDROCHLORIDE 1166-34-3
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
10 tons
Release date
2024-09-04

1166-34-3, CINANSERIN HYDROCHLORIDERelated Search:

Agelongine Anpirtoline hydrochloride 1-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine hydrochloride CINANSERIN HYDROCHLORIDE CINANSERIN HYDROCHLORIDE

  • N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE
  • N-[2-[[3-(DIMETHYLAMINO)PROPYL]THIO]PHENYL]-3-PHENYL-2-PROPENAMIDE HYDROCHLORIDE
  • 2'-(3-DIMETHYLAMINOPROPYL-THIO)-CINNAMANILIDE HYDROCHLORIDE
  • CINANSERIN
  • CINANSERIN HYDROCHLORIDE
  • DPTC
  • DPTC HYDROCHLORIDE
  • Cinanserine
  • N-[2-[[3-(Dimethylamino)propyl]thio]phenyl]-3-phenylpropenamide
  • 2-Propenamide, N-[2-[[3-(dimethylamino)propyl]thio]phenyl]-3-phenyl-
  • 1166-34-3
  • C20H25ClN2OS
  • Serotonin receptor