CINANSERIN HYDROCHLORIDE Property

Melting point:

82-83 °C

Boiling point:

519.5±50.0 °C(Predicted)

Density 

1.13±0.1 g/cm3(Predicted)

RTECS 

UC6323000

storage temp. 

Desiccate at RT

solubility 

Chloroform (Slightly), Methanol (Slightly)

form 

Solid

pka

13.46±0.70(Predicted)

color 

White to Off-White

Water Solubility 

Soluble to 50 mM in water

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P330Rinse mouth.

CINANSERIN HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Serotonin inhibitor.

Uses

A 5-HT antagonist

Definition

ChEBI: Cinanserin is an aryl sulfide that is (2E)-3-phenyl-N-(2-sulfanylphenyl)prop-2-enamide in which the hydrogen of the thiol group is substituted by a 3-(dimethylamino)propyl group. It is a 5-hydroxytryptamine receptor antagonist and an inhibitor of SARS-CoV replication. It has a role as an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an antiviral agent and an anticoronaviral agent. It is a tertiary amino compound, a secondary carboxamide, a member of cinnamamides and an aryl sulfide. It is a conjugate base of a cinanserin(1+).

Biological Activity

5-HT 2 antagonist.