ChemicalBook > CAS DataBase List > Broussonin E

Broussonin E

Product Name: Broussonin E
CAS No.: 90902-21-9
Chemical Name: Broussonin E
Synonyms: Broussonin E;2-[3-(3-Hydroxy-4-methoxyphenyl)propyl]-5-methoxyphenol;Phenol,2-[3-(3-hydroxy-4-methoxyphenyl)- propyl]-5-methoxy-
CBNumber: CB92566604
Molecular Formula: C17H20O4
Formula Weight: 288.34
MOL File: 90902-21-9.mol

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Broussonin E Property

solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form: Powder
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: AS021289
Product name: BroussoninE
Packaging: 5mg
Price: $339
Updated: 2021/12/16

Arctom

Product number: CFN97474
Product name: BroussoninE
Packaging: 5mg
Price: $553
Updated: 2021/12/16

Crysdot

Product number: CD32000143
Product name: BroussoninE
Purity: 95+%
Packaging: 5mg
Price: $860
Updated: 2021/12/16

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Broussonin E Chemical Properties,Usage,Production

Description

Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway, and can be further developed as a promising drug for the treatment of inflammation-related diseases such as atherosclerosis.

Uses

Broussonin E is a phenolic compound and shows anti-inflammatory activity. Broussonin E can suppress inflammation by modulating macrophages activation statevia inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathway. Broussonin E can be used for the research of inflammation-related diseases such as atherosclerosis[1].

target

TNF-α | p38 MAPK | ERK | JAK | STAT

IC 50

ERK; p38 MAPK; JAK2; STAT3; IL-1β; IL-6; COX-2; IL-10

References

[1] Huang SP, et al. Broussonin E suppresses LPS-induced inflammatory response in macrophages via inhibiting MAPK pathway and enhancing JAK2-STAT3 pathway. Chin J Nat Med. 2019 May 20;17(5):372-380. DOI:10.1016/S1875-5364(19)30043-3

Broussonin E Preparation Products And Raw materials

Raw materials

Preparation Products

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90902-21-9, Broussonin ERelated Search:

Hydroxyecdysone alpha-Cyperone alpha-Terpineol beta-Sitosterol (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one MOSLOFLAVONE beta-Eudesmol 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one hydroxygenkwanin Artemether

Broussonin E

2-[3-(3-Hydroxy-4-methoxyphenyl)propyl]-5-methoxyphenol

Phenol,2-[3-(3-hydroxy-4-methoxyphenyl)- propyl]-5-methoxy-

90902-21-9