4-iodo-2-Methyl-benzoic acid Methyl ester

Uses

Product Name: 4-iodo-2-Methyl-benzoic acid Methyl ester
CAS No.: 103440-53-5
Chemical Name: 4-iodo-2-Methyl-benzoic acid Methyl ester
Synonyms: Methyl 4-iodo-2-Methylbenzoate;4-iodo-2-Methyl-benzoic acid Methyl ester;Benzoic acid, 4-iodo-2-methyl-, methyl ester
CBNumber: CB92645367
Molecular Formula: C9H9IO2
Formula Weight: 276.07
MOL File: 103440-53-5.mol

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4-iodo-2-Methyl-benzoic acid Methyl ester Property

Boiling point:: 155 °C(Press: 17 Torr)
Density: 1.666±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
Appearance: Colorless to light yellow Liquid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M262748
Product name: Methyl4-Iodo-2-methylbenzoate
Packaging: 500mg
Price: $240
Updated: 2021/12/16

Ark Pharm

Product number: AK-77363
Product name: Methyl4-iodo-2-methylbenzoate
Purity: 97%
Packaging: 25g
Price: $364
Updated: 2021/12/16

Ark Pharm

Product number: AK-77363
Product name: Methyl4-iodo-2-methylbenzoate
Purity: 97%
Packaging: 100mg
Price: $10
Updated: 2021/12/16

Matrix Scientific

Product number: 149614
Product name: Methyl 4-iodo-2-methylbenzoate
Purity: 95%
Packaging: 5g
Price: $475
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0369447
Product name: METHYL-4-IODO-2-METHYLBENZOATE
Purity: 95.00%
Packaging: 5MG
Price: $495.81
Updated: 2021/12/16

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4-iodo-2-Methyl-benzoic acid Methyl ester Chemical Properties,Usage,Production

Uses

Methyl 4-iodo-2-methylbenzoate is an organic intermediate that can be prepared by diazotization followed by iodination of methyl 4-amino-2-methylbenzoate or by direct esterification of 4-iodo-2-methylbenzoic acid.

Synthesis

67-56-1

133232-58-3

103440-53-5

To a solution of 4-iodo-2-methylbenzoic acid (2 g, 7.62 mmol) in methanol (20 mL) at 0 °C was slowly added thionyl chloride (1.5 mL, 10.87 mmol). The reaction mixture was heated to reflux and stirred for 6 hours. Upon completion of the reaction, the solvent was removed by distillation and the residue was diluted with ethyl acetate (50 mL). The organic phase was washed sequentially with water (100 mL) and sodium bicarbonate solution (50 mL) and then dried over anhydrous sodium sulfate. The organic phase was concentrated under reduced pressure to give the crude product. The crude product was purified by silica gel column chromatography (eluent: 10% ethyl acetate in hexane solution) to afford methyl 4-iodo-2-methylbenzoate (1.8 g, 6.55 mmol, 85.7% yield) as a brown oily liquid.

References

[1] Patent: WO2016/154241, 2016, A1. Location in patent: Paragraph 560; 561
[2] Patent: US2005/143348, 2005, A1. Location in patent: Page/Page column 51

4-iodo-2-Methyl-benzoic acid Methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4-iodo-2-Methyl-benzoic acid Methyl ester Suppliers

China 46 India 1 United States 6 Global 53

Accela ChemBio Inc.

Tel: +1-858-6993322
Fax: (+1)-858-876-1948
Email: info@accelachem.com
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Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
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Aladdin Scientific

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Synthonix Inc

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Combi-Blocks Inc.

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Matrix Scientific

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Email: sales@matrixscientific.com
Country: United States
ProdList: 6632
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View Lastest Price from 4-iodo-2-Methyl-benzoic acid Methyl ester manufacturers

Career Henan Chemical Co

Product: 4-iodo-2-Methyl-benzoic acid Methyl ester 103440-53-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-14

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103440-53-5