Doxofylline
- Product Name
- Doxofylline
- CAS No.
- 69975-86-6
- Chemical Name
- Doxofylline
- Synonyms
- DOXOPHYLLINE;ventax;abc12/3;ansimar;Ansirnar;MAXIVENT;ABC 1213;DOXOFYLLINE;Doxofyliine;Doxof3rlline
- CBNumber
- CB9265231
- Molecular Formula
- C11H14N4O4
- Formula Weight
- 266.25
- MOL File
- 69975-86-6.mol
Doxofylline Property
- Melting point:
- 144-146°C
- Boiling point:
- 409.46°C (rough estimate)
- Density
- 1.2896 (rough estimate)
- refractive index
- 1.6000 (estimate)
- RTECS
- XH5135000
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 0.42±0.70(Predicted)
- color
- White to Off-White
- Water Solubility
- Soluble
- Merck
- 14,3438
- InChI
- InChI=1S/C11H14N4O4/c1-13-9-8(10(16)14(2)11(13)17)15(6-12-9)5-7-18-3-4-19-7/h6-7H,3-5H2,1-2H3
- InChIKey
- HWXIGFIVGWUZAO-UHFFFAOYSA-N
- SMILES
- N1(CC2OCCO2)C2=C(N(C)C(=O)N(C)C2=O)N=C1
- CAS DataBase Reference
- 69975-86-6(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P330Rinse mouth.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D4302
- Product name
- Doxofylline
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $36
- Updated
- 2024/03/01
- Product number
- D4302
- Product name
- Doxofylline
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $152
- Updated
- 2024/03/01
- Product number
- J60575
- Product name
- Doxofylline
- Packaging
- 5g
- Price
- $129.65
- Updated
- 2024/03/01
- Product number
- 18746
- Product name
- Doxofylline
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 18746
- Product name
- Doxofylline
- Purity
- ≥98%
- Packaging
- 5g
- Price
- $139
- Updated
- 2024/03/01
Doxofylline Chemical Properties,Usage,Production
Description
Doxofylline, a xanthine bronchodilator related to theophylline, is useful in the treatment of asthma and similar bronchospastic disorders. It has minimal activity on intestinal smooth muscle and the cardiovascular system, and is reportedly devoid of the behavioral effects of theophylline.
Description
Doxofylline is a methylxanthine bronchodilator that has been examined in clinical trials involving patients with either bronchial asthma or chronic obstructive pulmonary disease. Its mechanism of action is related to its ability to inhibit phosphodiesterase activity and, thus, increase cAMP. Compared to other xanthine derivatives, which have direct arrhythmogenic effects, doxofylline demonstrates decreased affinity towards adenosine A1 and A2 receptors, does not interfere with calcium influx into cells, and does not antagonize the action of calcium-channel blockers.
Originator
ABC S.p.A. (Italy)
Uses
Doxofylline is a xanthine molecule that appears to be both bronchodilator and anti-inflammatory with an improved therapeutic window over conventional xanthines such as Theophylline and the evidence supporting the effects of Doxofylline in the treatment of lung diseases.
Uses
H1 antihistamine
Definition
ChEBI: Doxofylline is an oxopurine that is a derivative of xanthine, methylated at N-1 and N-3 and carrying a 1,3-dioxolan-2-ylmethyl group at N-7, used in the treatment of asthma. It has a role as a bronchodilator agent, an antitussive and an anti-asthmatic drug. It is functionally related to a 7H-xanthine.
brand name
Maxivent (Roberts Pharmaceutical);ANSIMAR.
Doxofylline Preparation Products And Raw materials
Raw materials
Preparation Products
Doxofylline Suppliers
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- 024-45567608
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View Lastest Price from Doxofylline manufacturers
- Product
- Doxofylline 69975-86-6
- Price
- US $100.00-75.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000Ton
- Release date
- 2024-08-13
- Product
- Doxofylline 69975-86-6
- Price
- US $54.00-48.00/kg
- Min. Order
- 1kg
- Purity
- 99.99%
- Supply Ability
- 200Tons
- Release date
- 2023-03-28
- Product
- Doxofylline 69975-86-6
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-18