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IsochaMaejasMin

Product Name
IsochaMaejasMin
CAS No.
93859-63-3
Chemical Name
IsochaMaejasMin
Synonyms
IsochaMaejasMin;Isochamaejasmine;(2R,2'S,3S,3'R)-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bichroman]-4,4'-dione;(2R,2'S,3S,3'R)-rel-2,2',3,3'-Tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bi-4H-1-benzopyran]-4,4'-dione;[3,3'-Bi-4H-1-benzopyran]-4,4'-dione, 2,2',3,3'-tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-, (2R,2'S,3S,3'R)-rel-
CBNumber
CB92654626
Molecular Formula
C30H22O10
Formula Weight
542.49
MOL File
93859-63-3.mol
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IsochaMaejasMin Property

Boiling point:
932.6±65.0 °C(Predicted)
Density 
1.594±0.06 g/cm3(Predicted)
pka
7.14±0.60(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

CSNpharm
Product number
CSN14611
Product name
Isochamaejasmine
Packaging
1mg
Price
$370
Updated
2021/12/16
Arctom
Product number
AS014687
Product name
Isochamaejasmine
Packaging
5mg
Price
$371
Updated
2021/12/16
Arctom
Product number
CFN92150
Product name
Isochamaejasmine
Purity
≥98%
Packaging
5mg
Price
$418
Updated
2021/12/16
Crysdot
Product number
CD32000095
Product name
Isochamaejasmin
Purity
95+%
Packaging
5mg
Price
$810
Updated
2021/12/16
CSNpharm
Product number
CSN14611
Product name
Isochamaejasmine
Packaging
5mg
Price
$925
Updated
2021/12/16
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IsochaMaejasMin Chemical Properties,Usage,Production

Uses

Isochamaejasmin is a biflavonoid with anti-cancer, antiplasmodial and insecticidal activities. Isochamaejasmin displays a potent NF-κB (NF-κB) activation activity. Isochamaejasmin could cause DNA damage and induce apoptosis via the mitochondrial pathway in AW1 cells[1][2]. Isochamaejasmin also has a moderate antiplasmodial activity (IC50 of 7.3 μM for P. falciparum) and relatively low cytotoxicity (CC50 of 29.0 μM)[3].

Definition

ChEBI: A biflavonoid that consists of two units of 5,7,4'-trihydroxyflavanone joined together at position 3 and 3''.

References

[1] Yuanhang Ren, et al. Isochamaejasmin induces toxic effects on Helicoverpa zea via DNA damage and mitochondria-associated apoptosis. Pest Manag Sci. 2021 Jan;77(1):557-567. DOI:10.1002/ps.6055
[2] Qinghai Tian, et al. Stereospecific induction of nuclear factor-kappaB activation by isochamaejasmin. Mol Pharmacol. 2005 Dec;68(6):1534-42. DOI:10.1124/mol.105.014720
[3] Liene Dhooghe, et al. Antiplasmodial activity of (I-3,II-3)-biflavonoids and other constituents from Ormocarpum kirkii. Phytochemistry. 2010 May;71(7):785-91. DOI:10.1016/j.phytochem.2010.02.005

IsochaMaejasMin Preparation Products And Raw materials

Raw materials

Preparation Products

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IsochaMaejasMin Suppliers

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93859-63-3, IsochaMaejasMinRelated Search:

2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxy-2-methoxyphenyl)-8-[5-methyl-2-(1-methylvinyl)-4-hexenyl]-4H-1-benzopyran-4-one ISOPULEGOL, TECH. 6-HYDROXY-7-METHOXYCOUMARIN Isochamaejasmenin B Iso Altenuene (3β,20α)-17α-Hydroxyyohimban-16β-carboxylic acid methyl ester Isocarapanaubine Fluorescein isothiocyanate isomer I Isoengelitin alpha-Terpineol beta-Sitosterol alpha-Cyperone (4E,6E)-1,7-Diphenyl-4,6-heptadien-3-one 2-(3,4-Dihydroxyphenyl)-8-(2-O-beta-L-galactopyranosyl-beta-D-glucopyranosyl)-5,7-dihydroxy-4H-1-Benzopyran-4-one beta-Eudesmol MOSLOFLAVONE Hydroxyecdysone hydroxygenkwanin

  • IsochaMaejasMin
  • (2R,2'S,3S,3'R)-rel-2,2',3,3'-Tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bi-4H-1-benzopyran]-4,4'-dione
  • Isochamaejasmine
  • [3,3'-Bi-4H-1-benzopyran]-4,4'-dione, 2,2',3,3'-tetrahydro-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-, (2R,2'S,3S,3'R)-rel-
  • (2R,2'S,3S,3'R)-5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-[3,3'-bichroman]-4,4'-dione
  • 93859-63-3