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Irinotecan Hydroxyl Acid

Product Name
Irinotecan Hydroxyl Acid
CAS No.
142677-15-4
Chemical Name
Irinotecan Hydroxyl Acid
Synonyms
Irinotecan IMpurity;Irinotecan Impurity 28;Indolizino[1,2-b]quinoline-7-acetic acid, α,12-diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-, (αS)-;(S)-2-(12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic acid, sodium salt (1:2)
CBNumber
CB92665752
Molecular Formula
C22H22N2O6
Formula Weight
410.43
MOL File
142677-15-4.mol
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Irinotecan Hydroxyl Acid Property

Boiling point:
829.8±65.0 °C(Predicted)
Density 
1.54±0.1 g/cm3(Predicted)
solubility 
DMSO (Slightly, Heated), Methanol (Slightly, Sonicated), Water (Slightly)
form 
Solid
pka
2.88±0.10(Predicted)
color 
Light Yellow to Dark Yellow
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

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Irinotecan Hydroxyl Acid Chemical Properties,Usage,Production

Uses

The active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents.

Irinotecan Hydroxyl Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Irinotecan Hydroxyl Acid Suppliers

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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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142677-15-4, Irinotecan Hydroxyl AcidRelated Search:

12-ethyl-8-methyl-9-oxo-7-propionyl-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate (+)-Camptothecin N-Benzyl-4-piperidone 1-CHLOROCARBONYL-4-PIPERIDINOPIPERIDINE 4-Piperidinone Irinotecan Impurity 18 10-Hydroxycamptothecin 1-benzyl-4-(piperidin-1-yl)-1,2,3,6-tetrahydropyridine [1,4'-Bipiperidine]-1'-carboxylic acid Irinotecan Lactone IMpurity sodium:(2S)-2-[12-ethyl-8-(hydroxymethyl)-9-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)oxy-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate Irinotecan Impurity 26 Irinotecan 7,11-Diethyl-10-hydroxycaMptothecin Irinotecan Impurity 6 Irinotecan EP Impurity H 12-Hydroxy Irinotecan SN-38 GLUCURONIDE

  • Irinotecan IMpurity
  • Irinotecan Impurity 28
  • Indolizino[1,2-b]quinoline-7-acetic acid, α,12-diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-, (αS)-
  • (S)-2-(12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic acid, sodium salt (1:2)
  • 142677-15-4
  • 1426706-06-7