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EthanediaMide iMpurity F

Product Name: EthanediaMide iMpurity F
CAS No.: 480452-37-7
Chemical Name: EthanediaMide iMpurity F
Synonyms: Edoxaban-6;Edoxaban RC 4;Edoxaban iMpurities 6;Tropicamide Impurity 33;EthanediaMide iMpurity F;Edoxaban Impurity 3 Monomer;Edoxaban?Ethanediamide?Impurity;N-[(1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide;N1-{(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl}-N2-(5-chloropyridin-2-yl)ethanediamide;N1-[(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N2-(5-chloro-2-pyridinyl)ethanediamide
CBNumber: CB92676934
Molecular Formula: C16H22ClN5O3
Formula Weight: 367.83
MOL File: 480452-37-7.mol

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EthanediaMide iMpurity F Property

Density: 1.34±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
form: Solid
pka: 9.46±0.70(Predicted)
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0147989
Product name: Edoxabanimpurity6
Packaging: 5mg
Price: $400
Updated: 2021/12/16

ChemScene

Product number: CS-0147989
Product name: Edoxabanimpurity6
Packaging: 10mg
Price: $680
Updated: 2021/12/16

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EthanediaMide iMpurity F Chemical Properties,Usage,Production

Uses

Edoxaban impurity 6 is an impurity of Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention[1][2].

References

[1] Furugohri T, et al. DU-176b, a potent and orally active factor Xa inhibitor: in vitro and in vivo pharmacological profiles. J Thromb Haemost. 2008 Sep;6(9):1542-9. DOI:10.1111/j.1538-7836.2008.03064.x
[2] Mendell J, Lee F, Chen S, The Effects of the Antiplatelet Agents, Aspirin and Naproxen, on Pharmacokinetics and Pharmacodynamics of the Anticoagulant Edoxaban, a Direct Factor Xa Inhibitor. J Cardiovasc Pharmacol. 2013 Apr 23. DOI:10.1097/FJC.0b013e3182970991

EthanediaMide iMpurity F Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from EthanediaMide iMpurity F manufacturers

ZHUHAI HRD PHARMACEUTICAL CO., LTD.

Product: N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxycarbonyl) Amino ]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate 480452-37-7
Price: US $0.00/KG Ton
Min. Order: 1KG Ton
Purity: 99.5%+
Supply Ability: 2 tons/month
Release date: 2022-10-10

480452-37-7, EthanediaMide iMpurity FRelated Search:

2-(((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic acid 5-Methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid hydrochloride edoxaban carbamic acid, n-[(1r,2r,5s)-5-[(dimethylamino)carbonyl]-2-hydroxycyclohexyl]-, 1,1-dimethylethyl ester Ethyl 2-((5-chloropyridin-2-yl)amino)-2-oxoacetate hydrochloride (1R,2R,4S)-2-[(tert-butoxycarbonyl)aMino]-4-[(diMethylaMino)carbonyl]cyclohexyl Methanesulfonate Thiazolo[5,4-c]pyridine, 4,5,6,7-tetrahydro-5-methyl- EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2S,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- tert-Butyl [(1R,2S,5S)-2-amino-5-[(dimethylamino)carbonyl]cyclohexyl]carbamate oxalate EthanediaMide, N1-(5-chlo... EthanediaMide, N1-(5-chloro-2-pyridinyl)-N2-[(1S,2R,4R)-4-[(diMethylaMino)carbonyl]-2-[[(4,5,6,7-tetrahydro-5-Methylthiazolo[5,4-c]pyridin-2-yl)carbonyl]aMino]cyclohexyl]- (1R,3R,4R)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester (1S,3S,4S)-3-AMino-4-hydroxy-cyclohexanecarboxylic acid ethyl ester 2-Amino-6-chloropyridine EthanediaMide, N1-(5-chlo... EthanediaMide, N1-(5-chlo... (1S,3R,4S)-4-(2-((5-chloropyridin- 2-yl)amino)-2-oxoacetamido)-3-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylic acid 2-Amino-3-chloropyridine

N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxycarbonyl)Amino ]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate

EthanediaMide iMpurity F

N1-{(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl}-N2-(5-chloropyridin-2-yl)ethanediamide

Edoxaban-6

Edoxaban impurity 14/N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-2-[(tert-Butoxy carbonyl)Amino]-4-[(dimethylamino)carbonyl]-cyclohexyl) oxalamide dimethanesulfonate

Edoxaban iMpurities 6

Ethanediamide, N1-[(1S,2R,4S)-2-amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N2-(5-chloro-2-pyridinyl)-

N1-((1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide (Edoxaban Impurity)

Edoxaban RC 4

Edoxaban Impurity 54Q: What is Edoxaban Impurity 54 Q: What is the CAS Number of Edoxaban Impurity 54

Edoxaban Impurity 3 Monomer

Tropicamide Impurity 33

N1-[(1S,2R,4S)-2-Amino-4-[(dimethylamino)carbonyl]cyclohexyl]-N2-(5-chloro-2-pyridinyl)ethanediamide

Edoxaban?Ethanediamide?Impurity

N-[(1S,2R,4S)-2-Amino-4-(dimethylcarbamoyl)cyclohexyl]-N'-(5-chloropyridin-2-yl)oxamide

480452-37-7

C16H22ClN5O3