2-Amino-6-chloropyridine
- Product Name
- 2-Amino-6-chloropyridine
- CAS No.
- 45644-21-1
- Chemical Name
- 2-Amino-6-chloropyridine
- Synonyms
- 6-CHLORO-2-PYRIDINAMINE;2-CHLORO-6-AMINOPYRIDINE;2-Pyridinamine,6-chloro;2-CHIORO-6-AMINOPYRIDINE;6-AMINO-2-CHLOROPYRIDINE;6-Chloropyridine-2-amine;6-Chloro-2-aminopyridine;2-amino-6-chloro-pyridin;2-AMINO-6-CHLOROPYRIDINE;6-Chloro-2-pyridineamine
- CBNumber
- CB0138776
- Molecular Formula
- C5H5ClN2
- Formula Weight
- 128.56
- MOL File
- 45644-21-1.mol
2-Amino-6-chloropyridine Property
- Melting point:
- 69-73 °C
- Boiling point:
- 255.7±20.0 °C(Predicted)
- Density
- 1.326±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 2.76±0.24(Predicted)
- form
- Powder or Low Melting Solid
- color
- Orange to light brown
- BRN
- 108669
- InChI
- InChI=1S/C5H5ClN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8)
- InChIKey
- OBYJTLDIQBWBHM-UHFFFAOYSA-N
- SMILES
- C1(N)=NC(Cl)=CC=C1
- CAS DataBase Reference
- 45644-21-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,Xi
- Risk Statements
- 22-36/37/38
- Safety Statements
- 26-36/37-36
- WGK Germany
- 3
- RTECS
- US1813350
- Hazard Note
- Harmful/Irritant
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H312Harmful in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A2263
- Product name
- 2-Amino-6-chloropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $72
- Updated
- 2025/07/31
- Product number
- 415337
- Product name
- 2-Amino-6-chloropyridine
- Packaging
- 1g
- Price
- $319
- Updated
- 2021/12/16
- Product number
- A602895
- Product name
- 2-Amino-6-chloropyridine
- Packaging
- 50g
- Price
- $565
- Updated
- 2021/12/16
- Product number
- 023713
- Product name
- 2-Amino-6-chloropyridine
- Purity
- 97%
- Packaging
- 5g
- Price
- $10
- Updated
- 2021/12/16
- Product number
- I211
- Product name
- 2-Amino-6-chloropyridine
- Packaging
- 5g
- Price
- $14
- Updated
- 2021/12/16
2-Amino-6-chloropyridine Chemical Properties,Usage,Production
Chemical Properties
White to light yellow powder
Uses
Substrate used in a Ni(II)-catalyzed homo-coupling providing diamino-2,2′-bipyridine.
Uses
2-Amino-6-chloropyridine used in a Ni(II)-catalyzed homo-coupling providing diamino-2,2′-bipyridine.
Synthesis
94166-64-0
45644-21-1
The general procedure for the synthesis of 2-amino-6-chloropyridine from 2-chloro-6-nitropyridine was as follows: the TAPEHA-Pd catalyst (0.015 g) was added to EtOH/water (1:1, 20 mL) solution containing nitroaromatics (1.0 mmol). Upon slow addition of NaBH4 (4.0 mmol), the color of the reaction mixture gradually changed to black within a few minutes, indicating the formation of palladium nanoparticles (TAPEHA-PdNPs). The reaction was stirred continuously for 1.5 h at room temperature and atmospheric pressure. After completion of the reaction, the catalyst was removed by filtration and the reaction solution was extracted with EtOAc (3 × 30 mL). The organic layers were combined, dried with MgSO4 and subsequently concentrated under vacuum.
References
[1] Turkish Journal of Chemistry, 2017, vol. 41, # 5, p. 784 - 792
[2] Catalysis Communications, 2015, vol. 67, p. 64 - 67
2-Amino-6-chloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-6-chloropyridine manufacturers
- Product
- 2-Amino-6-chloropyridine 45644-21-1
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-02
- Product
- 2-Amino-6-chloropyridine 45644-21-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-10
- Product
- 2-Amino-6-chloropyridine 45644-21-1
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27