2-Amino-3-chloropyridine
Application- Product Name
- 2-Amino-3-chloropyridine
- CAS No.
- 39620-04-7
- Chemical Name
- 2-Amino-3-chloropyridine
- Synonyms
- AURORA 15088;IFLAB-BB F3099-7175;OTAVA-BB BB7110951381;Pyridinamine, 3-chloro;3-Choro-2-pyridinamine;2-AMino-3-chloropyridi;Amino-3-Chloropyridine;3-CHLOROPYRIDIN-2-AMINE;3-Chloro-2-pyridinamine;3-CHLOROPYPRIDIN-2-AMINE
- CBNumber
- CB0185482
- Molecular Formula
- C5H5ClN2
- Formula Weight
- 128.56
- MOL File
- 39620-04-7.mol
2-Amino-3-chloropyridine Property
- Melting point:
- 59-62℃
- Boiling point:
- 207.0±20.0 °C(Predicted)
- Density
- 1.326±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- powder to crystal
- pka
- 4.14±0.36(Predicted)
- color
- White to Orange to Green
- InChI
- InChI=1S/C5H5ClN2/c6-4-2-1-3-8-5(4)7/h1-3H,(H2,7,8)
- InChIKey
- RZJPBQGRCNJYBU-UHFFFAOYSA-N
- SMILES
- C1(N)=NC=CC=C1Cl
- CAS DataBase Reference
- 39620-04-7(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-41-37/38-22-20/21/22
- Safety Statements
- 26-36/37/39-39-36/37-24/25
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- 734691
- Product name
- 2-Amino-3-chloropyridine
- Purity
- 97%
- Packaging
- 1g
- Price
- $22.1
- Updated
- 2025/07/31
- Product number
- A2497
- Product name
- 2-Amino-3-chloropyridine
- Purity
- >98.0%(GC)(T)
- Packaging
- 1g
- Price
- $81
- Updated
- 2025/07/31
- Product number
- A576870
- Product name
- 2-Amino-3-chloropyridine
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 3H30-5-06
- Product name
- 3-Chloropyridin-2-amine
- Purity
- 95%
- Packaging
- 1g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- 3H30-5-06
- Product name
- 3-Chloropyridin-2-amine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $35
- Updated
- 2021/12/16
2-Amino-3-chloropyridine Chemical Properties,Usage,Production
Application
3-Chloro-2-aminopyridine belongs to the pyridine derivatives and is an intermediate in organic synthesis and pharmaceutical chemistry. Industrially, it can be used as a dyeing agent and in the synthesis of active pharmaceutical ingredients.
Chemical Properties
Light green solid
Synthesis Reference(s)
Journal of Heterocyclic Chemistry, 24, p. 1313, 1987 DOI: 10.1002/jhet.5570240516
Synthesis
54231-32-2
39620-04-7
The general procedure for the synthesis of 3-chloro-2-aminopyridine from 3-chloro-2-nitropyridine was as follows: 3-chloro-2-nitropyridine (1.00 g, 6.31 mmol) was dissolved in methanol (10 mL), and stannic(II) chloride (5.98 g, 31.54 mmol) and concentrated hydrochloric acid (2.63 mL, 31.54 mmol) were added sequentially. The reaction mixture was stirred at room temperature overnight. After completion of the reaction, the reaction solution was diluted with ethyl acetate and washed with 1N NaOH solution. Subsequently, the organic phase was washed with saturated NaHCO3 solution and dried with anhydrous Na2SO4. Finally, the organic phase was concentrated under reduced pressure to afford the target product 3-chloro-2-aminopyridine (510.0 mg, 63% yield). The product was characterized by 1H NMR (400 MHz, CD3CN) with chemical shifts of δ 6.80 (m, 1H), 7.60 (d, 1H), 8.12 (d, 1H).
References
[1] Patent: WO2006/44775, 2006, A2. Location in patent: Page/Page column 64
[2] Patent: US2009/22670, 2009, A1. Location in patent: Page/Page column 25
2-Amino-3-chloropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Amino-3-chloropyridine manufacturers
- Product
- 2-Amino-3-chloropyridine 39620-04-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-04-30
- Product
- 2-Amino-3-chloropyridine 39620-04-7
- Price
- US $5.00-2.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000kg
- Release date
- 2024-08-20
- Product
- 2-Amino-3-chloropyridine 39620-04-7
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11