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2-Amino-6-chloropyridine

Product Name
2-Amino-6-chloropyridine
CAS No.
45644-21-1
Chemical Name
2-Amino-6-chloropyridine
Synonyms
6-CHLORO-2-PYRIDINAMINE;2-CHLORO-6-AMINOPYRIDINE;2-Pyridinamine,6-chloro;2-CHIORO-6-AMINOPYRIDINE;6-AMINO-2-CHLOROPYRIDINE;6-Chloropyridine-2-amine;6-Chloro-2-aminopyridine;2-amino-6-chloro-pyridin;2-AMINO-6-CHLOROPYRIDINE;6-Chloro-2-pyridineamine
CBNumber
CB0138776
Molecular Formula
C5H5ClN2
Formula Weight
128.56
MOL File
45644-21-1.mol
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2-Amino-6-chloropyridine Property

Melting point:
69-73 °C
Boiling point:
255.7±20.0 °C(Predicted)
Density 
1.326±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
2.76±0.24(Predicted)
form 
Powder or Low Melting Solid
color 
Orange to light brown
BRN 
108669
InChI
InChI=1S/C5H5ClN2/c6-4-2-1-3-5(7)8-4/h1-3H,(H2,7,8)
InChIKey
OBYJTLDIQBWBHM-UHFFFAOYSA-N
SMILES
C1(N)=NC(Cl)=CC=C1
CAS DataBase Reference
45644-21-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22-36/37/38
Safety Statements 
26-36/37-36
WGK Germany 
3
RTECS 
US1813350
Hazard Note 
Harmful/Irritant
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
A2263
Product name
2-Amino-6-chloropyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$72
Updated
2025/07/31
Usbiological
Product number
415337
Product name
2-Amino-6-chloropyridine
Packaging
1g
Price
$319
Updated
2021/12/16
TRC
Product number
A602895
Product name
2-Amino-6-chloropyridine
Packaging
50g
Price
$565
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA07273
Product name
2-Amino-6-chloropyridine
Packaging
100g
Price
$250
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA07273
Product name
2-Amino-6-chloropyridine
Packaging
250g
Price
$500
Updated
2021/12/16
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2-Amino-6-chloropyridine Chemical Properties,Usage,Production

Chemical Properties

White to light yellow powder

Uses

Substrate used in a Ni(II)-catalyzed homo-coupling providing diamino-2,2′-bipyridine.

Uses

2-Amino-6-chloropyridine used in a Ni(II)-catalyzed homo-coupling providing diamino-2,2′-bipyridine.

Synthesis

94166-64-0

45644-21-1

The general procedure for the synthesis of 2-amino-6-chloropyridine from 2-chloro-6-nitropyridine was as follows: the TAPEHA-Pd catalyst (0.015 g) was added to EtOH/water (1:1, 20 mL) solution containing nitroaromatics (1.0 mmol). Upon slow addition of NaBH4 (4.0 mmol), the color of the reaction mixture gradually changed to black within a few minutes, indicating the formation of palladium nanoparticles (TAPEHA-PdNPs). The reaction was stirred continuously for 1.5 h at room temperature and atmospheric pressure. After completion of the reaction, the catalyst was removed by filtration and the reaction solution was extracted with EtOAc (3 × 30 mL). The organic layers were combined, dried with MgSO4 and subsequently concentrated under vacuum.

References

[1] Turkish Journal of Chemistry, 2017, vol. 41, # 5, p. 784 - 792
[2] Catalysis Communications, 2015, vol. 67, p. 64 - 67

2-Amino-6-chloropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Amino-6-chloropyridine Suppliers

Americas 1 Belgium 1 China 314 Europe 3 France 2 Germany 9 India 48 Ireland 1 Japan 3 Slovakia 1 Switzerland 4 The Netherlands 1 United Kingdom 20 United States 50 Global 458
Acros Organics (Part of Thermo Fisher Scientific )
Tel
--
Fax
--
Email
fo@acros.com
Country
Belgium
ProdList
3824
Advantage
58
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View Lastest Price from 2-Amino-6-chloropyridine manufacturers

Dideu Industries Group Limited
Product
2-Amino-6-chloropyridine 45644-21-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-02
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Amino-6-chloropyridine 45644-21-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
2-Amino-6-chloropyridine 45644-21-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-27

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  • 2-Pyridinamine,6-chloro
  • 2-amino-6-chloro-pyridin
  • 6-CHLOROPYRIDIN-2-YLAMINE
  • 6-CHLORO-2-PYRIDINAMINE
  • 6-AMINO-2-CHLOROPYRIDINE
  • 2-CHIORO-6-AMINOPYRIDINE
  • 2-AMINO-6-CHLOROPYRIDINE (6-CHLOROPYRIDIN-2-YLAMINE)
  • 2-Pyridinamine,6-chloro-(9CI)
  • 6-Chloro-2-aminopyridine
  • 6-Chloropyridine-2-amine
  • 2-Amino-6-chloropyridine,98%
  • 2-CHLORO-6-AMINOPYRIDINE
  • 2-AMINO-6-CHLOROPYRIDINE
  • 2-Amino-6-chloropyridine &gt
  • 2-Amino-6-chloropyridine ISO 9001：2015 REACH
  • 6-Chloro-2-pyridineamine
  • 45644-21-1
  • Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Pyridines
  • Building Blocks
  • PYRIDINE
  • pyridine derivative
  • Amines
  • Pyridines
  • Building Blocks
  • C5
  • C5 to C6
  • Chemical Synthesis
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • amine| alkyl chloride
  • Isoquinolines ,Heterocyclic Acids