HEMATOPORPHYRIN DIHYDROCHLORIDE

Product Name: HEMATOPORPHYRIN DIHYDROCHLORIDE
CAS No.: 17696-69-4
Chemical Name: HEMATOPORPHYRIN DIHYDROCHLORIDE
Synonyms: ematoporfirina;Hemaloporphyrin;Hematoporphyrin 2HCl;HematoporphyrineDihcl;HAEMATOPORPHYRINDICHLORIDE;Haematopophyrin dihydrochloride;HEMATOPORPHYRIN DIHYDROCHLORIDE;HAEMATOPORPHYRIN DIHYDROCHLORIDE;HEMATOPORPHYRIN IX DIHYDROCHLORIDE;HAEMATOPORPHYRIN Dihydrochloride(RG)
CBNumber: CB9281835
Molecular Formula: C34H39ClN4O6
Formula Weight: 635.16
MOL File: 17696-69-4.mol

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HEMATOPORPHYRIN DIHYDROCHLORIDE Property

storage temp.: Inert atmosphere,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Very Dark Red
Water Solubility: Insoluble in water. Soluble in pyridine (5%).
Merck: 14,4636
BRN: 78957
Stability:: Hygroscopic
EPA Substance Registry System: 21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, dihydrochloride (17696-69-4)

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Safety

Risk Statements: 33
RTECS: TS5505000
TSCA: Yes
Toxicity: mouse,LD50,intraperitoneal,169mg/kg (169mg/kg),BEHAVIORAL: TREMORBEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY),Bollettino Chimico Farmaceutico. Vol. 117, Pg. 145, 1978.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28287
Product name: Hematoporphyrin (hydrochloride)
Packaging: 250mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 28287
Product name: Hematoporphyrin (hydrochloride)
Packaging: 500mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 28287
Product name: Hematoporphyrin (hydrochloride)
Packaging: 100mg
Price: $32
Updated: 2024/03/01

TRC

Product number: H245683
Product name: HematoporphyrinDihydrochloride
Packaging: 500mg
Price: $120
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FH52434
Product name: Hematoporphyrin dihydrochloride
Packaging: 500mg
Price: $125
Updated: 2021/12/16

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HEMATOPORPHYRIN DIHYDROCHLORIDE Chemical Properties,Usage,Production

Description

Hematoporphyrin is a photosensitizer. Hematoporphyrin (3 μM) increases oxygen consumption and decreases the respiratory control ratio (RCR) in irradiated isolated rat liver mitochondria. It induces DNA breaks in cell-free assays, but not in human HeLa cervical cancer cells, in a light-dependent manner when used at a concentration of 6 μM. Hematoporphyrin (12 μM) decreases the survival of irradiated, but not non-irradiated, HeLa cells. Hematoporphyrin (5 mg/kg) decreases growth of subcutaneous Yoshida AH-130 hepatoma tumors in rats when administered with radiation.

Uses

Endogenous porphyrin formed by the acid hydrolysis of hemoglobin. It is employed as an active pharmaceutical intermediate.

References

[1] KESSEL D. Hematoporphyrin and HPD: photophysics, photochemistry and phototherapy.[J]. Photochemistry and Photobiology, 1984, 39 6: 851-859. DOI: 10.1111/j.1751-1097.1984.tb08871.x
[2] C SALET G M. Photodynamic effects of haematoporphyrin on respiration and calcium uptake in isolated mitochondria.[J]. International journal of radiation biology and related studies in physics, chemistry, and medicine, 1981, 39 2: 227-230. DOI: 10.1080/09553008114550261
[3] M. EGYEKI . DNA damaging capability of hematoporphyrin towards DNAs of various accessibilities[J]. Journal of photochemistry and photobiology. B, Biology, 2006, 84 2: Pages 119-127. DOI: 10.1016/j.jphotobiol.2006.02.005
[4] L TOMIO. Effect of hematoporphyrin and red light on AH-130 solid tumors in rats.[J]. Acta radiologica. Oncology, 1983, 22 1: 49-53. DOI: 10.3109/02841868309134338

HEMATOPORPHYRIN DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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HEMATOPORPHYRIN DIHYDROCHLORIDE Suppliers

China 110 Europe 2 France 1 Germany 3 India 1 Japan 1 Switzerland 2 United Kingdom 8 United States 21 Global 149

J & K SCIENTIFIC LTD.

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View Lastest Price from HEMATOPORPHYRIN DIHYDROCHLORIDE manufacturers

Dideu Industries Group Limited

Product: HEMATOPORPHYRIN DIHYDROCHLORIDE 17696-69-4
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-07-26

Career Henan Chemical Co

Product: HEMATOPORPHYRIN DIHYDROCHLORIDE 17696-69-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1
Release date: 2018-08-06

17696-69-4, HEMATOPORPHYRIN DIHYDROCHLORIDERelated Search:

Cysteamine hydrochloride Triethylamine hydrochloride Naphthylethylenediamine hydrochloride 2,2′-Azobis(2-methylpropionamidine) dihydrochloride N-(1-Naphthyl)ethylenediamine dihydrochloride 2-Aminoethylammonium chloride Dimethylamine hydrochloride HEMATOPORPHYRIN 3-PENTEN-2-OL Allylacetic acid PORPHINE HEMATOPORPHYRIN DIHYDROCHLORIDE 7,12-diethyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid 3-METHYL-3-BUTEN-2-OL 5-METHYL-4-HEXENOIC ACID 4-METHYL-3-PENTEN-2-OL HEMATOPORPHYRIN HYDROCHLORIDE DEUTEROPORPHYRIN IX DIHYDROCHLORIDE

21h,23h-porphine-2,18-dipropanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-tetr

21h,23h-porphine-2,18-propanoicacid,7,12-bis(1-hydroxyethyl)-3,8,13,17-tetr

7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-2,18-porphinedipropionicacid

acido1,3,5,8-tetrametil-2,4-bis(idrossietil)porpfina-6,7-dipropionicodiclor

ematoporfirina

HEMATOPORPHYRIN IX DIHYDROCHLORIDE

HEMATOPORPHYRIN DIHYDROCHLORIDE

HAEMATOPORPHYRIN DIHYDROCHLORIDE

8,13-BIS(1-HYDROXYETHYL)-3,7,12,17-TETRAMETHYL-21H,23H-PORPHINE-2,18-DIPROPIONIC ACID DIHYDROCHLORIDE

Haematopophyrin dihydrochloride

HematoporphyrineDihcl

Hemaloporphyrin

HAEMATOPORPHYRIN Dihydrochloride(RG)

HAEMATOPORPHYRINDICHLORIDE

7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoic acid hydrochloride

8,13-Bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionic acid dihydrochloride

21H,23H-Porphine-2,18-dipropanoic acid, 7,12-bis(1-hydroxyethyl)-3,8,13,17-tetramethyl-, hydrochloride (1:2)

HematoporphyrinIXdihydrochloride,8,13-Bis(1-hydroxyethyl)-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionicaciddihydrochloride

HEMATOPORPHYRIN DIHYDROCHLORIDE USP/EP/BP

3,3'-(7,12-Bis(1-hydroxyethyl)-3,8,13,17-tetramethylporphyrin-2,18-diyl)dipropionic acid dihydrochloride

Hematoporphyrin 2HCl

17696-69-4

C34H38N4O62HCl

C34H40Cl2N4O6

C34H38N4O6HCl

C34H38N4O62ClH

Porphyrins

Natural Porphyrins and Derivitives

Porphyrins

Biochemistry

Miscellaneous Biochemicals

porphine (porphyrin) ligand