Description Sources
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2,5-Dimethylindole

Description Sources
Product Name
2,5-Dimethylindole
CAS No.
1196-79-8
Chemical Name
2,5-Dimethylindole
Synonyms
2,5-DIMETHYLINDOLE;2,5-Dimethylindole>Indole, 2,5-dimethyl-;2,5-Dimethylindole 97%;2,5-Dimethylindole,97%;2,5-DIMETHYL-1H-INDOLE;1H-Indole, 2,5-dimethyl-
CBNumber
CB9283268
Molecular Formula
C10H11N
Formula Weight
145.2
MOL File
1196-79-8.mol
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2,5-Dimethylindole Property

Melting point:
112-113 °C (lit.)
Boiling point:
254.33°C (rough estimate)
Density 
1.0353 (rough estimate)
refractive index 
1.5000 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
soluble in Methanol
form 
Solid
pka
17.75±0.30(Predicted)
color 
Off-white to pale pink or light brown
CAS DataBase Reference
1196-79-8(CAS DataBase Reference)
NIST Chemistry Reference
1H-indole, 2,5-dimethyl-(1196-79-8)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-39
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D166006
Product name
2,5-Dimethylindole
Purity
97%
Packaging
1g
Price
$26.3
Updated
2023/06/20
TCI Chemical
Product number
D3698
Product name
2,5-Dimethylindole
Purity
>97.0%(GC)
Packaging
1g
Price
$64
Updated
2024/03/01
TCI Chemical
Product number
D3698
Product name
2,5-Dimethylindole
Purity
>97.0%(GC)
Packaging
5g
Price
$254
Updated
2024/03/01
Alfa Aesar
Product number
H66874
Product name
2,5-Dimethylindole, 97%
Packaging
1g
Price
$64.1
Updated
2023/06/20
Alfa Aesar
Product number
H66874
Product name
2,5-Dimethylindole, 97%
Packaging
5g
Price
$248
Updated
2023/06/20
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2,5-Dimethylindole Chemical Properties,Usage,Production

Description

2, 5-Dimethylindole is a kind of carbazole-system derived indole compound, which is valuable in the manufacturing of perfume. It is also a useful chemical intermediate. It is usually used as reactant in the following reaction: stereoselective synthesis of indolines via palladium-catalyzed asymmetric hydrogenation of unprotected indoles; stereoselective preparation of substituted indoles via rhodium-catalyzed enantioselective coupling reaction of indoles with diazo compounds; enantioselective synthesis of fluorene derivatives via Friedel-Crafts reactions; preparation of bis-indolyldihydroxybenzoquinones by addition indoles to dichlorobenzoquinone promoted by Bronsted acid; Reaction with hydroxypyrazolines.

Sources

https://www.sigmaaldrich.com/catalog/product/aldrich/d166006?lang=en&region=US
https://books.google.com/books?isbn=0470188073

Chemical Properties

Off-white to pale pink or light brown solid

Uses

  • Reactant in stereoselective preparation of substituted indoles via rhodium-catalyzed enantioselective coupling reaction of indoles with diazo compounds
  • Reactant in stereoselective synthesis of indolines via palladium-catalyzed asymmetric hydrogenation of unprotected indoles
  • Reactant in enantioselective synthesis of fluorene derivatives via Friedel-Crafts reactions
  • Reactant in preparation of bis-indolyldihydroxybenzoquinones by addition indoles to dichlorobenzoquinone promoted by Bronsted acid
  • Reactant in reaction with hydroxypyrazolines

2,5-Dimethylindole Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-Dimethylindole Suppliers

CHEMOS GmbH & Co. KG
Tel
--
Fax
--
Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from 2,5-Dimethylindole manufacturers

Career Henan Chemical Co
Product
2,5-Dimethylindole 1196-79-8
Price
US $1.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
Customized
Release date
2018-12-17