ChemicalBook > CAS DataBase List > PARATHYROID HORMONE (1-34), BOVINE

PARATHYROID HORMONE (1-34), BOVINE

Description

Product Name: PARATHYROID HORMONE (1-34), BOVINE
CAS No.: 12583-68-5
Chemical Name: PARATHYROID HORMONE (1-34), BOVINE
Synonyms: BPTH 1-34;TERIPARATIDE;PTH (1-34) (BOVINE);bovineparathyroidhormone(1-34;AVSEIQFMHNLGKHLSSMERVEWLRKKLQDVHNF;PARATHYROID HORMONE (1-34), BOVINE;parathyroid hormone fragment 1-34 bovine;PARATHYROID HORMONE BOVINE: FRAGMENT 1-34;ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE;H-ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-OH
CBNumber: CB9284467
Molecular Formula: C183H288N54O50S2
Formula Weight: 4108.71
MOL File: Mol file

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PARATHYROID HORMONE (1-34), BOVINE Property

storage temp.: −20°C
solubility: ≥410.9 mg/mL in DMSO; ≥43.8 mg/mL in H2O; ≥64.6 mg/mL in EtOH
form: powder
color: White to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P3671
Product name: Parathyroid Hormone Fragment 1-34 bovine
Purity: ≥97% (HPLC), powder
Packaging: 0.1mg
Price: $335.97
Updated: 2025/07/31

ApexBio Technology

Product number: A1114
Product name: Parathyroid Hormone (1-34), bovine
Packaging: 5mg
Price: $300
Updated: 2021/12/16

ApexBio Technology

Product number: A1114
Product name: Parathyroid Hormone (1-34), bovine
Packaging: 1mg
Price: $100
Updated: 2021/12/16

ApexBio Technology

Product number: A1114
Product name: Parathyroid Hormone (1-34), bovine
Packaging: 10mg
Price: $500
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb372676
Product name: Parathyroid Hormone (1-34) (Bovine)
Purity: > 95%
Packaging: 1mg
Price: $669.8
Updated: 2021/12/16

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PARATHYROID HORMONE (1-34), BOVINE Chemical Properties,Usage,Production

Description

Parathyroid hormone (PTH) is an 84 amino acid hormone involved in calcium regulation in counteraction to calcitonin. PTH regulates serum phosphate levels and vitamin D biosynthesis. N-terminal peptides of PTH are used to elicit and study a wide variety of responses in target cells.

Uses

Parathyroid Hormone (1-34), bovine is a potent parathyroid hormone (PTH) receptor agonist. Parathyroid Hormone (1-34), bovine increases calcium and inorganic phosphate levels in vivo. Parathyroid Hormone (1-34), bovine can be used for th reseach of osteoporosis[1].

Clinical Use

Active fragment (1-34) of endogenous human parathyroid hormone:
Treatment of osteoporosis in postmenopausal women and men at increased risk of fractures
Treatment of corticosteroid-induced osteoporosis

Side effects

Teriparatide, parathyroid hormone (1–34), is the only anabolic agent available in the United States for the treatment of postmenopausal osteoporosis. Side effects that human should report to doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
blood in the urine; pain in the lower back or side; pain when urinating
signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
signs and symptoms of increased calcium like nausea; vomiting; constipation; low energy; or muscle weakness

in vivo

Parathyroid Hormone (1-34)(subcutaneous?injection; 80 μg/kg; 5 days) increases serum osteocalcin concentrations without changing serum inorganic phosphate or calcium concentrations in either group of old animals.?Serum 1,25-dihydroxyvitamin D concentrations are significantly higher in the PTH-treated senile female rats than the sex-matchedvehicle-treated controls^[1].

Metabolism

No metabolism or excretion studies have been performed. Peripheral metabolism of PTH is believed to occur by non-specific enzymatic mechanisms in the liver followed by excretion via the kidneys. The 24-hour urine excretion of calcium was reduced by a clinically unimportant amount (15%).

References

[1] B H Mitlak, et al. Intermittent administration of bovine PTH-(1-34) increases serum 1,25-dihydroxyvitamin D concentrations and spinal bone density in senile (23 month) rats. J Bone Miner Res. 1992 May;7(5):479-84. DOI:10.1002/jbmr.5650070503
[2] M Takigawa, et al. Studies on chondrocytes from mandibular condylar cartilage, nasal septal cartilage, and spheno-occipital synchondrosis in culture. I. Morphology, growth, glycosaminoglycan synthesis, and responsiveness to bovine parathyroid hormone (1-34). J Dent Res. 1984 Jan;63(1):19-22. DOI:10.1177/00220345840630010201

PARATHYROID HORMONE (1-34), BOVINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from PARATHYROID HORMONE (1-34), BOVINE manufacturers

Ningbo Qingteng Plastic Cost.,Ltd.

Product: Teriparatide 12583-68-5
Price: US $10.00-7.00/VIAL
Min. Order: 10VIAL
Purity: 99.9
Supply Ability: 20000
Release date: 2025-11-25

Ningbo Qingteng Plastic Cost.,Ltd.

Product: Cortagen 12583-68-5
Price: US $10.00-7.00/VIAL
Min. Order: 10VIAL
Purity: 99.9
Supply Ability: 20000
Release date: 2025-11-25

Shanghai Yimeixin Technology Co., LTD

Product: Teriparatide 12583-68-5
Price: US $0.00/Box
Min. Order: 1Box
Purity: 99%
Supply Ability: 10tons
Release date: 2025-10-13

12583-68-5, PARATHYROID HORMONE (1-34), BOVINERelated Search:

PTH (1-31) (HUMAN) PTH (1-84) (RAT) Parathyroid Hormone (1-38), human PARATHYROID HORMONE (1-34), RAT PTH (1-34) (PORCINE) PTH (1-84) (HUMAN) pTH (1-84) (dog) H-SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-NH2 PTH (13-34) (HUMAN) H-SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-VAL-ALA-LEU-OH GLU-ALA-ASP-LYS-ALA-ASP-VAL-ASN-VAL-LEU-THR-LYS-ALA-LYS-SER-GLN ALA-PRO-LEU-ALA-PRO-ARG-ASP-ALA-GLY-SER-GLN-ARG-PRO-ARG-LYS-LYS-GLU-ASP-ASN-VAL-LEU-VAL-GLU-SER-HIS-GLU-LYS-SER-LEU-GLY-GLU-ALA-ASP-LYS-ALA-ASP-VAL-ASN-VAL-LEU-THR-LYS-ALA-LYS-SER-GLN PARATHYROID HORMONE (39-68), HUMAN ostabolin pTH (1-44) (human)|Parathyroid Hormone (1-44), human TERT-BUTYL ISOCYANIDE Tris(2,4-pentanedionato)chroMiuM(III) Tosylmethyl isocyanide

ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE

ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE BOVINE

H-ALA-VAL-SER-GLU-ILE-GLN-PHE-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-SER-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-OH

AVSEIQFMHNLGKHLSSMERVEWLRKKLQDVHNF

BPTH 1-34

PTH (1-34) (BOVINE)

TERIPARATIDE

PARATHYROID HORMONE (1-34), BOVINE

PARATHYROID HORMONE BOVINE: FRAGMENT 1-34

bovineparathyroidhormone(1-34

SER-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ASN-SER-MET-GLU-ARG-VAL-GLU-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE: SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNF

parathyroid hormone fragment 1-34 bovine

12583-68-5

C183H288N54O50S2

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