Sulfamerazine sodium

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Sulfamerazine sodium

Product Name: Sulfamerazine sodium
CAS No.: 127-58-2
Chemical Name: Sulfamerazine sodium
Synonyms: Nsc226823;solumedine;sulfamerazine sodium;SODIUM SULFAMERAZINE;sodiumsulphamerazine;solublesulfamerazine;Pyrimidine sodium sulfa;SULFAMERAZINE SODIUM SALT;SulfadimidineSodium,Pharma;Sulfamerazine sodium USP/EP/BP
CBNumber: CB9289260
Molecular Formula: C11H13N4NaO2S
Formula Weight: 288.3
MOL File: 127-58-2.mol

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Sulfamerazine sodium Property

RTECS: WP0760000
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Powder
Water Solubility: Soluble in DMSO or water
CAS DataBase Reference: 127-58-2(CAS DataBase Reference)
EPA Substance Registry System: Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt (127-58-2)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/22-36/38-36/37/38
Safety Statements: 7-24-45-36-26
WGK Germany: 3
TSCA: Yes

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S0800
Product name: Sulfamerazine sodium salt
Packaging: 250g
Price: $162
Updated: 2024/03/01

Alfa Aesar

Product number: J66717
Product name: Sulfamerazine sodium salt
Packaging: 250g
Price: $150
Updated: 2024/03/01

Cayman Chemical

Product number: 23380
Product name: Sulfamerazine (sodium salt)
Purity: ≥98%
Packaging: 10g
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 23380
Product name: Sulfamerazine (sodium salt)
Purity: ≥98%
Packaging: 50g
Price: $56
Updated: 2024/03/01

Cayman Chemical

Product number: 23380
Product name: Sulfamerazine (sodium salt)
Purity: ≥98%
Packaging: 100g
Price: $78
Updated: 2024/03/01

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Sulfamerazine sodium Chemical Properties,Usage,Production

Description

Sulfamerazine is a sulfonamide antibiotic. It inhibits bacterial carbonic anhydrase by ~20% at a concentration of 500 μM. In vivo, sulfamerazine (500 mg/L) reduces severity of peribronchitis and inhibits cilia-associated respiratory Bacillus colonization in mice. It also prevents death of Toxoplasma-infected mice. Sulfonamide class antibiotics, of which sulfamerazine is a member, are bacteriostatic and inhibit bacterial synthesis of dihydrofolic acid by competing with 4-aminobenzoic acid for binding to dihydropteroate synthase. Formulations containing sulfamerazine have been used for the treatment of pneumonia and typhoid fever.

Uses

Involved in characterization of chirosan membranes for the transport of drugs1,2,3

brand name

Bio hubber simple;Cremo-merazine;Debnal m;Mebacid;Neotrizine;Peccocode;Septosil;Spanbolet ii;Tersulpha;Trisulfaminic;Trisulpha.

World Health Organization (WHO)

Sulfamerazine sodium, a sulfonamide anti-infective agent, was introduced several decades ago for the treatment of bacterial infections. The importance of sulfonamides has subsequently decreased as a result of increasing resistance and their replacement by antibiotics which are generally more active and less toxic. The sulfonamides are known to cause serious adverse effects such as renal toxicity, sometimes fatal exfoliative dermatitis and erythema multiforma and dangerous adverse reactions affecting blood formation such as agranulocytosis and haemolytic or aplastic anaemia. Sulfamerazine is still used in some countries usually in combination with other sulfonamides.

Safety Profile

Moderately toxic by ingestion, subcutaneous, intraperitoneal, and intravenous routes. When heated to decomposition it emits toxic fumes of SOx, NOx, and Na2O.

Sulfamerazine sodium Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sulfamerazine sodium manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Sulfamerazine Sodium 127-58-2
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2024-04-03

Hebei Duling International Trade Co. LTD

Product: Sulfamerazine sodium 127-58-2
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2023-03-29

Baoji Guokang Healthchem co.,ltd

Product: Sulfamerazine sodium 127-58-2
Price: US $80.00/Kg/Bag
Min. Order: 1Kg/Bag
Purity: 99%
Supply Ability: 10000kg
Release date: 2021-06-04

127-58-2, Sulfamerazine sodiumRelated Search:

Sulfamethazine Sulfadiazine Sodium sulfadiazine METSULFURON METHYL Sodium citrate Sodium bicarbonate Sulfadimethoxine Methyl salicylate Sodium hydroxide Sodium chloride Sodium sulfate Silver sulfadiazine Sulfamerazine Sodium acetate Methyl acetate Sodium chlorite Tribenuron methyl Diclofenac sodium

solumedine

SODIUM SULFAMERAZINE

sulfamerazine sodium

SULFAMERAZINE SODIUM SALT

SULFAMERAZINE, SODIUM SALT MONOHYDRATE

monosodium 2-sulfanilamido-4-methylpyrimidine

2-sulfanilamido-4-methylpyrimidine sodium salt

4-AMINO-N-[4-METHYL-2-PYRIMIDINYL]-BENZENESULFONAMIDE SODIUM SALT

4-methyl-2-sulfanilamidopyrimidine sodium salt

4-amino-n-(4-methyl-2-pyrimidinyl)-benzenesulfonamidmonosodiumsalt

n(sup1)-(4-methyl-2-pyrimidinyl)sulfanilamidesodiumsalt

(4-aminophenyl)sulfonyl-(4-methylpyrimidin-2-yl)azanide

n(sup1)-(4-methyl-2-pyrimidinyl)-sulfanilamidmonosodiumsalt

sodiumsulphamerazine

solublesulfamerazine

SULFAMERAZINE SODIUM(SM1-NA)(NDC:56631-1715)

Pyrimidine sodium sulfa

SulfadimidineSodium,Pharma

Benzenesulfonamide, 4-amino-N-(4-methyl-2-pyrimidinyl)-, monosodium salt

Nsc226823

sodium,(4-aminophenyl)sulfonyl-(4-methylpyrimidin-2-yl)azanide

Sulfamerazine sodium USP/EP/BP

127-58-2

C11H11N4NaO2S

C11H11N4O2SNa

Heterocyclic Building Blocks

Pyrimidines

Building Blocks

C9 to C11

Chemical Synthesis

Heterocyclic Building Blocks

Pyrimidines